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The map label for this gene is accDA [H]

Identifier: 38233386

GI number: 38233386

Start: 767461

End: 768966

Strand: Reverse

Name: accDA [H]

Synonym: DIP0787

Alternate gene names: 38233386

Gene position: 768966-767461 (Counterclockwise)

Preceding gene: 38233392

Following gene: 38233383

Centisome position: 30.9

GC content: 56.18

Gene sequence:

>1506_bases
ATGACCCGAACGACCGCACACGAGCTCATAGCCCAGGTTCTCGACACCGATTCTTTTCATAGTTGGGATACCGCACCGGT
CTATGGGGATATCTCAGAAAGCTACCAACAATTCCTTGCCAAGGCCCGCGAAAAATCAGGGGTAGACGAATCCGTAATCA
CAGGTGAGGGCACTGTTTATGGCCACCGCGTTGCCGTGGTCCTCAGCGAATTCAACTTCCTCGGTGGCTCTATCGGAGCC
GCTACCGCCCGACGCATCATTGCAGCAATTCACAAAGCAACTGAACAGCGCCTACCGCTCCTTATTTCGCCTTCTTCAGG
CGGTACTCGTATGCAGGAAGGCACCCCCGCTTTTGCCCTCATGGTATCCATCACCACCGCCGTGTACCGACACAAAGACG
CACACCTGCCCTACTTGGTGTATCTTCGCAATCCCACGACTGGTGGCGTTATGGCTTCTTGGGGGTCTGCGGGCCACTTC
ACTTTCGCTGAACCCGATGCATTATTGGGTTTTCTGGGTCCGCGCGTCGTTGAGCTCACCACTGGTCGCCCGCTTACCCA
AGGTGTGCAGTCGGGTGAAAATCTGGCCGAAAAAGGAGTCATCGACGGCGTTATTTCCCCACGGGAGCTACGCGCGTCGC
TGAAAAAGATTGTCGAGGTCATTCTGAGCCCCGCAGACGTGACCGCAACACCCCACAGCGACCCCTGCCAAATCGATTCT
GATCGCCACAGCGTATGGGAGTCGATTGAGACTACTCGGCATATTGATCGACCCGGCGCGCGCAGCATCATGCATGCCAT
CGGTCGCGATAATTATGTTCAGCTTTTTGGCAGTGGCGACGGCCGACGCTCCCCCGCTGTGATTGTGGCCGTGGCTCGTC
TTGCGGGGCGCAGTGCTGTGATTATTGCTCAGGATCGTCATGCGCAGCCCCCTCATGCCACCACGGAGCTTGGCACTGAG
GCATTACGCTGCGCTCGGCGCGGCATTCTACTTGCCCATGAGCTGCAGCTTCCGTTGATTTCTATTATTGATACTCCGGG
TGCTGAGCTCAGCGACTATGCCGAAGAGCATGGTTTGGCAGGTTCGATTGCTCGTACTCTCAGTGAGCTTGTGTCGGTAG
ATGTTCCGACGCTGTCTCTCATTTTGGGCCAAGGCTGTGGCGGGGGTGCTTTGGCTATGCTTCCGGCGGACAAGGTTCTT
GCGACTTCTCATGCATGGTTGAGCCCTCTTCCTCCAGAGGGCGCCTCTGCGATTATTTATCGCGATACGTCCCATGCGGC
ACAAATGATGGAGGAACAGCAAGTTTCGGCGGTAACACTCAAAGAGGTTGGCATTATCGACGCCATTATCGACGAACCTG
TCGCTGCGCATCAGCATCCTGACGCTTTTGCGACTTGTGTGCTTGAGAAGGTTACTGCGGCTCTCGCCGAACTGGATGAT
TCTCCCGCGGTGGGACGCGAGTCCCGTTTACAGCGCTACGAAAAGCTCGCCCACACATTGATCTAA

Upstream 100 bases:

>100_bases
GTCACCATTCAACACCGATAATCCACCCTATGCACCCCCTATTGGCAAATTTTTGCACAATTTCTGCACCAACCACTCGT
GTTCTTTATAGGGTGGTGCC

Downstream 100 bases:

>100_bases
CGATGTGACGGTGATTTGATGCATAACGCCCGTAGATCGCGAATTTGTCTACGGGCGTTATTGTTGCTTCTTATTGTTGT
GTGCGACTAGCCGACGTTGA

Product: putative carboxyltransferase subunit of acetyl-CoA carboxylase

Products: NA

Alternate protein names: ACCase beta chain [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MTRTTAHELIAQVLDTDSFHSWDTAPVYGDISESYQQFLAKAREKSGVDESVITGEGTVYGHRVAVVLSEFNFLGGSIGA
ATARRIIAAIHKATEQRLPLLISPSSGGTRMQEGTPAFALMVSITTAVYRHKDAHLPYLVYLRNPTTGGVMASWGSAGHF
TFAEPDALLGFLGPRVVELTTGRPLTQGVQSGENLAEKGVIDGVISPRELRASLKKIVEVILSPADVTATPHSDPCQIDS
DRHSVWESIETTRHIDRPGARSIMHAIGRDNYVQLFGSGDGRRSPAVIVAVARLAGRSAVIIAQDRHAQPPHATTELGTE
ALRCARRGILLAHELQLPLISIIDTPGAELSDYAEEHGLAGSIARTLSELVSVDVPTLSLILGQGCGGGALAMLPADKVL
ATSHAWLSPLPPEGASAIIYRDTSHAAQMMEEQQVSAVTLKEVGIIDAIIDEPVAAHQHPDAFATCVLEKVTAALAELDD
SPAVGRESRLQRYEKLAHTLI

Sequences:

>Translated_501_residues
MTRTTAHELIAQVLDTDSFHSWDTAPVYGDISESYQQFLAKAREKSGVDESVITGEGTVYGHRVAVVLSEFNFLGGSIGA
ATARRIIAAIHKATEQRLPLLISPSSGGTRMQEGTPAFALMVSITTAVYRHKDAHLPYLVYLRNPTTGGVMASWGSAGHF
TFAEPDALLGFLGPRVVELTTGRPLTQGVQSGENLAEKGVIDGVISPRELRASLKKIVEVILSPADVTATPHSDPCQIDS
DRHSVWESIETTRHIDRPGARSIMHAIGRDNYVQLFGSGDGRRSPAVIVAVARLAGRSAVIIAQDRHAQPPHATTELGTE
ALRCARRGILLAHELQLPLISIIDTPGAELSDYAEEHGLAGSIARTLSELVSVDVPTLSLILGQGCGGGALAMLPADKVL
ATSHAWLSPLPPEGASAIIYRDTSHAAQMMEEQQVSAVTLKEVGIIDAIIDEPVAAHQHPDAFATCVLEKVTAALAELDD
SPAVGRESRLQRYEKLAHTLI
>Mature_500_residues
TRTTAHELIAQVLDTDSFHSWDTAPVYGDISESYQQFLAKAREKSGVDESVITGEGTVYGHRVAVVLSEFNFLGGSIGAA
TARRIIAAIHKATEQRLPLLISPSSGGTRMQEGTPAFALMVSITTAVYRHKDAHLPYLVYLRNPTTGGVMASWGSAGHFT
FAEPDALLGFLGPRVVELTTGRPLTQGVQSGENLAEKGVIDGVISPRELRASLKKIVEVILSPADVTATPHSDPCQIDSD
RHSVWESIETTRHIDRPGARSIMHAIGRDNYVQLFGSGDGRRSPAVIVAVARLAGRSAVIIAQDRHAQPPHATTELGTEA
LRCARRGILLAHELQLPLISIIDTPGAELSDYAEEHGLAGSIARTLSELVSVDVPTLSLILGQGCGGGALAMLPADKVLA
TSHAWLSPLPPEGASAIIYRDTSHAAQMMEEQQVSAVTLKEVGIIDAIIDEPVAAHQHPDAFATCVLEKVTAALAELDDS
PAVGRESRLQRYEKLAHTLI

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=442, Percent_Identity=24.8868778280543, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI295821216, Length=462, Percent_Identity=24.2424242424242, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788655, Length=226, Percent_Identity=34.9557522123894, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1786382, Length=256, Percent_Identity=32.03125, Blast_Score=119, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI25147362, Length=457, Percent_Identity=24.2888402625821, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25147359, Length=457, Percent_Identity=24.2888402625821, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 53502; Mature: 53371

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTTAHELIAQVLDTDSFHSWDTAPVYGDISESYQQFLAKAREKSGVDESVITGEGTVY
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCEE
GHRVAVVLSEFNFLGGSIGAATARRIIAAIHKATEQRLPLLISPSSGGTRMQEGTPAFAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHH
MVSITTAVYRHKDAHLPYLVYLRNPTTGGVMASWGSAGHFTFAEPDALLGFLGPRVVELT
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCEECCCCCCCCEECCHHHHHHHCCCEEEEEE
TGRPLTQGVQSGENLAEKGVIDGVISPRELRASLKKIVEVILSPADVTATPHSDPCQIDS
CCCCHHHHHHCCHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DRHSVWESIETTRHIDRPGARSIMHAIGRDNYVQLFGSGDGRRSPAVIVAVARLAGRSAV
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEE
IIAQDRHAQPPHATTELGTEALRCARRGILLAHELQLPLISIIDTPGAELSDYAEEHGLA
EEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHCCCCEEEECCCCCHHHHHHHHCCCH
GSIARTLSELVSVDVPTLSLILGQGCGGGALAMLPADKVLATSHAWLSPLPPEGASAIIY
HHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCCEEEE
RDTSHAAQMMEEQQVSAVTLKEVGIIDAIIDEPVAAHQHPDAFATCVLEKVTAALAELDD
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHCCC
SPAVGRESRLQRYEKLAHTLI
CCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRTTAHELIAQVLDTDSFHSWDTAPVYGDISESYQQFLAKAREKSGVDESVITGEGTVY
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCEE
GHRVAVVLSEFNFLGGSIGAATARRIIAAIHKATEQRLPLLISPSSGGTRMQEGTPAFAL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHH
MVSITTAVYRHKDAHLPYLVYLRNPTTGGVMASWGSAGHFTFAEPDALLGFLGPRVVELT
HHHHHHHHHHCCCCCCCEEEEEECCCCCCCEECCCCCCCCEECCHHHHHHHCCCEEEEEE
TGRPLTQGVQSGENLAEKGVIDGVISPRELRASLKKIVEVILSPADVTATPHSDPCQIDS
CCCCHHHHHHCCHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DRHSVWESIETTRHIDRPGARSIMHAIGRDNYVQLFGSGDGRRSPAVIVAVARLAGRSAV
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEE
IIAQDRHAQPPHATTELGTEALRCARRGILLAHELQLPLISIIDTPGAELSDYAEEHGLA
EEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHCCCCEEEECCCCCHHHHHHHHCCCH
GSIARTLSELVSVDVPTLSLILGQGCGGGALAMLPADKVLATSHAWLSPLPPEGASAIIY
HHHHHHHHHHHHCCCCHHHHHHCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCCEEEE
RDTSHAAQMMEEQQVSAVTLKEVGIIDAIIDEPVAAHQHPDAFATCVLEKVTAALAELDD
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHCCC
SPAVGRESRLQRYEKLAHTLI
CCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]