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The map label for this gene is serC [H]

Identifier: 38233383

GI number: 38233383

Start: 763738

End: 764868

Strand: Reverse

Name: serC [H]

Synonym: DIP0784

Alternate gene names: 38233383

Gene position: 764868-763738 (Counterclockwise)

Preceding gene: 38233386

Following gene: 38233382

Centisome position: 30.73

GC content: 54.2

Gene sequence:

>1131_bases
ATGAGCGAGTACCCTATTCTTCCCAGTACCCTGATCCCCGCCGATCCGCGCTTTGGATGTGGCCCATCTAAAGTTCGCCC
AGCACAACTGAACGCCATCGTTAATGCTGGCGCAGATGTTATCGGCACTTCTCATCGTCAGCCAGCTGTGAAGAACATTG
TTGGAAGTATCCGAGAGGGCCTTTCCTCCCTCTTTTCACTACCAGATGGCTACGAGATCGTACTTTCTTTGGGTGGCGCC
ACCGCTTTCTGGGATGCAGCAACCTTCGGTTTAATTGAGAAGAAGTCCGGACACCTCACTTTTGGCGAGTTCTCCGGCAA
GTTCGCAAAGGCATCTGCTCAAGCACCGTGGTTGGACGAACCTACGATTATTTCCGCCGAGCCAGGCGATACACCTACCC
CTGTGGCCATGGAGGGCTGCGACGTTATCGCGTGGGCACACAATGAGACGTCGACAGGCGCTATGGTTCCCGTTATTCGT
CCAGAAAATTCTGATGGCCAGCTCGTAGCTATCGACGCCACCTCTGGTGCCGGCGGACTGCCCGTGGATATGCACAATGC
CGATGTTTATTACTTCTCTCCTCAGAAGTGCTTTGCCTCCGATGGTGGTTTGTGGCTTGCAGCGATGAGCCCTGCAGCCT
TGGAGCGTATTGAGAAGATCAATGCTTCGGACCGTTTCATTCCGGCATTCCTCAACCTCCAGACTGCTGTGGACAATTCC
CGTAAGAACCAGACCTACAACACCCCTGCTGTAGGCACGCTTTTGATGCTGGAGAACCAAGTGGAGTGGATGAACGCCAA
TGGTGGCCTTGATGCCATGGTTGAACGCACCACCGCTAATTCTTCCGCATTGTACGAATGGGCAGAAAAGCGCGCTGAAA
CAACTCCTTATGTAACCGATCCTGCGAAGCGTTCTCTGGTCGTGGGCACTATTGACTTTGATGATTCCATTGATGCCGCT
GCGCTAGCTAAGGTGCTACGCGCCAACGGAATCCTCGACGTAGAGCCTTATCGCAAGCTAGGCCGCAACCAGCTGCGTAT
CGGTATGTTCCCTGCCATCGATACCGCCGATATGGACACACTGACCGCCGCCATCGACTACGTCCTCGACAACGGTTTCG
CCCAAGCGTAA

Upstream 100 bases:

>100_bases
TTCCACCTCATGGGCGGCACTGCCACCCCACTGATGCGGACAAATCTTTTGAGTCCTTATCCCTTTTTGTGCGTTGTCCT
ACAACGAGAAAGCGTGACAC

Downstream 100 bases:

>100_bases
TTCCTATCCGTTTCTTTTCCCCTTAGCTCAGACGATGCCACTTTTATGGTTGCCGCTGAGCTAAGGAATATTTTGTCAGT
TCGGCAATTTCTTTCGGCAC

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSEYPILPSTLIPADPRFGCGPSKVRPAQLNAIVNAGADVIGTSHRQPAVKNIVGSIREGLSSLFSLPDGYEIVLSLGGA
TAFWDAATFGLIEKKSGHLTFGEFSGKFAKASAQAPWLDEPTIISAEPGDTPTPVAMEGCDVIAWAHNETSTGAMVPVIR
PENSDGQLVAIDATSGAGGLPVDMHNADVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPAFLNLQTAVDNS
RKNQTYNTPAVGTLLMLENQVEWMNANGGLDAMVERTTANSSALYEWAEKRAETTPYVTDPAKRSLVVGTIDFDDSIDAA
ALAKVLRANGILDVEPYRKLGRNQLRIGMFPAIDTADMDTLTAAIDYVLDNGFAQA

Sequences:

>Translated_376_residues
MSEYPILPSTLIPADPRFGCGPSKVRPAQLNAIVNAGADVIGTSHRQPAVKNIVGSIREGLSSLFSLPDGYEIVLSLGGA
TAFWDAATFGLIEKKSGHLTFGEFSGKFAKASAQAPWLDEPTIISAEPGDTPTPVAMEGCDVIAWAHNETSTGAMVPVIR
PENSDGQLVAIDATSGAGGLPVDMHNADVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPAFLNLQTAVDNS
RKNQTYNTPAVGTLLMLENQVEWMNANGGLDAMVERTTANSSALYEWAEKRAETTPYVTDPAKRSLVVGTIDFDDSIDAA
ALAKVLRANGILDVEPYRKLGRNQLRIGMFPAIDTADMDTLTAAIDYVLDNGFAQA
>Mature_375_residues
SEYPILPSTLIPADPRFGCGPSKVRPAQLNAIVNAGADVIGTSHRQPAVKNIVGSIREGLSSLFSLPDGYEIVLSLGGAT
AFWDAATFGLIEKKSGHLTFGEFSGKFAKASAQAPWLDEPTIISAEPGDTPTPVAMEGCDVIAWAHNETSTGAMVPVIRP
ENSDGQLVAIDATSGAGGLPVDMHNADVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPAFLNLQTAVDNSR
KNQTYNTPAVGTLLMLENQVEWMNANGGLDAMVERTTANSSALYEWAEKRAETTPYVTDPAKRSLVVGTIDFDDSIDAAA
LAKVLRANGILDVEPYRKLGRNQLRIGMFPAIDTADMDTLTAAIDYVLDNGFAQA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=372, Percent_Identity=23.6559139784946, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI10863955, Length=321, Percent_Identity=23.6760124610592, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17506897, Length=362, Percent_Identity=22.3756906077348, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356589, Length=366, Percent_Identity=24.0437158469945, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR006272
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40102; Mature: 39970

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYPILPSTLIPADPRFGCGPSKVRPAQLNAIVNAGADVIGTSHRQPAVKNIVGSIREG
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHH
LSSLFSLPDGYEIVLSLGGATAFWDAATFGLIEKKSGHLTFGEFSGKFAKASAQAPWLDE
HHHHHCCCCCEEEEEEECCCHHHHHHHHHCEEECCCCCEEECCCCCCEEECCCCCCCCCC
PTIISAEPGDTPTPVAMEGCDVIAWAHNETSTGAMVPVIRPENSDGQLVAIDATSGAGGL
CEEEECCCCCCCCCEEECCCCEEEEECCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCC
PVDMHNADVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPAFLNLQTAVDNS
EEEECCCEEEEECCHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCEEEHHHHHHHHHCCC
RKNQTYNTPAVGTLLMLENQVEWMNANGGLDAMVERTTANSSALYEWAEKRAETTPYVTD
CCCCCCCCCCCEEEEEEECCEEEEECCCCHHHEEEECCCCCHHHHHHHHHHCCCCCCEEC
PAKRSLVVGTIDFDDSIDAAALAKVLRANGILDVEPYRKLGRNQLRIGMFPAIDTADMDT
CCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEECHHHHHCCCCCEEEEECCCCCCCCHHH
LTAAIDYVLDNGFAQA
HHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SEYPILPSTLIPADPRFGCGPSKVRPAQLNAIVNAGADVIGTSHRQPAVKNIVGSIREG
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHH
LSSLFSLPDGYEIVLSLGGATAFWDAATFGLIEKKSGHLTFGEFSGKFAKASAQAPWLDE
HHHHHCCCCCEEEEEEECCCHHHHHHHHHCEEECCCCCEEECCCCCCEEECCCCCCCCCC
PTIISAEPGDTPTPVAMEGCDVIAWAHNETSTGAMVPVIRPENSDGQLVAIDATSGAGGL
CEEEECCCCCCCCCEEECCCCEEEEECCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCC
PVDMHNADVYYFSPQKCFASDGGLWLAAMSPAALERIEKINASDRFIPAFLNLQTAVDNS
EEEECCCEEEEECCHHHHCCCCCEEEEECCHHHHHHHHHCCCCCCEEEHHHHHHHHHCCC
RKNQTYNTPAVGTLLMLENQVEWMNANGGLDAMVERTTANSSALYEWAEKRAETTPYVTD
CCCCCCCCCCCEEEEEEECCEEEEECCCCHHHEEEECCCCCHHHHHHHHHHCCCCCCEEC
PAKRSLVVGTIDFDDSIDAAALAKVLRANGILDVEPYRKLGRNQLRIGMFPAIDTADMDT
CCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEECHHHHHCCCCCEEEEECCCCCCCCHHH
LTAAIDYVLDNGFAQA
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA