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The map label for this gene is mtrA2 [H]

Identifier: 38233301

GI number: 38233301

Start: 668619

End: 669317

Strand: Direct

Name: mtrA2 [H]

Synonym: DIP0694

Alternate gene names: 38233301

Gene position: 668619-669317 (Clockwise)

Preceding gene: 38233300

Following gene: 38233302

Centisome position: 26.87

GC content: 51.79

Gene sequence:

>699_bases
ATGGAAAGGACCACGGACGGTATGGCACCGAAAATTTTGGTTGTCGACGATGATCCCGCGATTTCAGAGATGCTGACCAT
CGTGCTGGAGGCCGAGGGATTTGAGCCGGTCGCGGTCACTGATGGGGCAGTAGCAGTTGATGCCTTTAGGACAGAATCGC
CTGATCTAGTCCTACTCGATTTGATGCTGCCTGGTATGAATGGCATCGACATTTGTAGGATAATCCGGCAGGAATCGGCA
GTTCCTATCGTCATGCTCACGGCGAAAACCGACACCGTGGACGTAGTCCTTGGTTTGGAATCAGGTGCAGATGACTACAT
CAACAAGCCGTTTAAGCCGAAAGAACTCATCGCTCGACTACGTGCACGCTTGCGTCGTACAGAGGACTCTCCGTCCGAAA
CCATTGAGATCGGGGATCTTACGATCGACGTCCTAGGCCACGAAGTCACTCGAGGAGATGAGGAAATTCAACTCACTCCT
TTAGAGTTTGATTTGCTGCTTGAGCTTGCAAGCAAACCAGGACAGGTGTTCACACGTGAGGAACTTCTGCAAAAAGTTTG
GGGCTACCGTAATGCCTCAGACACGAGACTGGTGAATGTCCATGTGCAGCGACTGCGCTCAAAGATCGAGAAAGACCCAG
AAAACCCGCACATCGTGTTAACAGTGCGCGGAGTGGGGTATAAGACAGGGCAGGAGTAG

Upstream 100 bases:

>100_bases
CGGATACGGTGACTCAACGAATTATTCAAGCGCTCAGTGCATAACTGAGGCTACGATGAGGTGCTAAGACACCTATTGGG
CTCGCATGTGAGCCGCTTAC

Downstream 100 bases:

>100_bases
CTCGCTATTTATCGGGGTGTTTCTCGGGTACGTCATCGCATTGCAGAACTGTGGCGTACCTCGTTGCAATTTAAGGTTCT
AGGCTCCATTTTTGCCGCTT

Product: putative two component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MERTTDGMAPKILVVDDDPAISEMLTIVLEAEGFEPVAVTDGAVAVDAFRTESPDLVLLDLMLPGMNGIDICRIIRQESA
VPIVMLTAKTDTVDVVLGLESGADDYINKPFKPKELIARLRARLRRTEDSPSETIEIGDLTIDVLGHEVTRGDEEIQLTP
LEFDLLLELASKPGQVFTREELLQKVWGYRNASDTRLVNVHVQRLRSKIEKDPENPHIVLTVRGVGYKTGQE

Sequences:

>Translated_232_residues
MERTTDGMAPKILVVDDDPAISEMLTIVLEAEGFEPVAVTDGAVAVDAFRTESPDLVLLDLMLPGMNGIDICRIIRQESA
VPIVMLTAKTDTVDVVLGLESGADDYINKPFKPKELIARLRARLRRTEDSPSETIEIGDLTIDVLGHEVTRGDEEIQLTP
LEFDLLLELASKPGQVFTREELLQKVWGYRNASDTRLVNVHVQRLRSKIEKDPENPHIVLTVRGVGYKTGQE
>Mature_232_residues
MERTTDGMAPKILVVDDDPAISEMLTIVLEAEGFEPVAVTDGAVAVDAFRTESPDLVLLDLMLPGMNGIDICRIIRQESA
VPIVMLTAKTDTVDVVLGLESGADDYINKPFKPKELIARLRARLRRTEDSPSETIEIGDLTIDVLGHEVTRGDEEIQLTP
LEFDLLLELASKPGQVFTREELLQKVWGYRNASDTRLVNVHVQRLRSKIEKDPENPHIVLTVRGVGYKTGQE

Specific function: Member of the two-component regulatory system mtrA/mtrB [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=45.374449339207, Blast_Score=187, Evalue=5e-49,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=40.3508771929825, Blast_Score=167, Evalue=5e-43,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=38.5650224215247, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=40.8888888888889, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=38.9908256880734, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=36.6515837104072, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=34.9344978165939, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1786784, Length=219, Percent_Identity=40.6392694063927, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=40.8888888888889, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=36.697247706422, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=31.5789473684211, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=34.6491228070175, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.9775784753363, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=30.1369863013699, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790299, Length=137, Percent_Identity=30.6569343065693, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=35.5140186915888, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790437, Length=124, Percent_Identity=33.0645161290323, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25756; Mature: 25756

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERTTDGMAPKILVVDDDPAISEMLTIVLEAEGFEPVAVTDGAVAVDAFRTESPDLVLLD
CCCCCCCCCCEEEEECCCHHHHHHEEEEEECCCCCCEEEECCEEEEEEECCCCCCEEEEE
LMLPGMNGIDICRIIRQESAVPIVMLTAKTDTVDVVLGLESGADDYINKPFKPKELIARL
EECCCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCHHHHCCCCCHHHHHHHH
RARLRRTEDSPSETIEIGDLTIDVLGHEVTRGDEEIQLTPLEFDLLLELASKPGQVFTRE
HHHHHCCCCCCCCEEEECCEEEEEECCHHCCCCCEEEEECCHHHHHHHHHCCCCCEECHH
ELLQKVWGYRNASDTRLVNVHVQRLRSKIEKDPENPHIVLTVRGVGYKTGQE
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MERTTDGMAPKILVVDDDPAISEMLTIVLEAEGFEPVAVTDGAVAVDAFRTESPDLVLLD
CCCCCCCCCCEEEEECCCHHHHHHEEEEEECCCCCCEEEECCEEEEEEECCCCCCEEEEE
LMLPGMNGIDICRIIRQESAVPIVMLTAKTDTVDVVLGLESGADDYINKPFKPKELIARL
EECCCCCCHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCCCHHHHCCCCCHHHHHHHH
RARLRRTEDSPSETIEIGDLTIDVLGHEVTRGDEEIQLTPLEFDLLLELASKPGQVFTRE
HHHHHCCCCCCCCEEEECCEEEEEECCHHCCCCCEEEEECCHHHHHHHHHCCCCCEECHH
ELLQKVWGYRNASDTRLVNVHVQRLRSKIEKDPENPHIVLTVRGVGYKTGQE
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]