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The map label for this gene is groES

Identifier: 38233184

GI number: 38233184

Start: 543376

End: 543672

Strand: Direct

Name: groES

Synonym: DIP0575

Alternate gene names: 38233184

Gene position: 543376-543672 (Clockwise)

Preceding gene: 38233183

Following gene: 38233185

Centisome position: 21.83

GC content: 55.89

Gene sequence:

>297_bases
GTGGCTAACGTCAATATCAAGCCTTTGGAGGACCGCGTCCTCGTTCAGATCAGCGAAGCTGAGACCACCACCGCTTCTGG
TTTGGTGATTCCAGATTCTGCTAAGGAGAAGCCACAGGAAGGCGTCGTCGTCGCTGCAGGCCCAGGCCGCTTCGATGGTG
ATGACCGCGTTCCTATGGACATCAAGGAGGGCGACACCGTTGTGTTCTCCAAGTACGGCGGAACCGAGTTGAAGTACAAC
GGCGAAGAGTACTTGCTGCTCAACGCTCGCGACGTTCTCGCCATCATCGAGAAGTAA

Upstream 100 bases:

>100_bases
CAGTAGGTTGTAACTCACACAGTTGTTCACCCGCGACGACGGCTGTGCTGGATTTCCCACAACCGGCACAAAGAGAAACT
TCATGTAACGGAGGTATATC

Downstream 100 bases:

>100_bases
GGCAGCCCCCGTATGGCAAAGCTGATTGCATTTAATCAAGAAGCACGCGAAGGCATCCTCAAGGGTGTCGACGCACTGGC
CAACGCAGTCAAGGTGACCT

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MANVNIKPLEDRVLVQISEAETTTASGLVIPDSAKEKPQEGVVVAAGPGRFDGDDRVPMDIKEGDTVVFSKYGGTELKYN
GEEYLLLNARDVLAIIEK

Sequences:

>Translated_98_residues
MANVNIKPLEDRVLVQISEAETTTASGLVIPDSAKEKPQEGVVVAAGPGRFDGDDRVPMDIKEGDTVVFSKYGGTELKYN
GEEYLLLNARDVLAIIEK
>Mature_97_residues
ANVNIKPLEDRVLVQISEAETTTASGLVIPDSAKEKPQEGVVVAAGPGRFDGDDRVPMDIKEGDTVVFSKYGGTELKYNG
EEYLLLNARDVLAIIEK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=43.75, Blast_Score=74, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=37.2340425531915, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324594, Length=96, Percent_Identity=41.6666666666667, Blast_Score=65, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358317, Length=102, Percent_Identity=41.1764705882353, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=39.1752577319588, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_CORDI (Q6NJ38)

Other databases:

- EMBL:   BX248355
- RefSeq:   NP_938951.1
- ProteinModelPortal:   Q6NJ38
- SMR:   Q6NJ38
- GeneID:   2648771
- GenomeReviews:   BX248353_GR
- KEGG:   cdi:DIP0575
- NMPDR:   fig|257309.1.peg.542
- HOGENOM:   HBG703377
- OMA:   RVIYARY
- PhylomeDB:   Q6NJ38
- ProtClustDB:   PRK00364
- BioCyc:   CDIP257309:DIP0575-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10607; Mature: 10476

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVNIKPLEDRVLVQISEAETTTASGLVIPDSAKEKPQEGVVVAAGPGRFDGDDRVPMD
CCCCCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCCCEE
IKEGDTVVFSKYGGTELKYNGEEYLLLNARDVLAIIEK
ECCCCEEEEECCCCEEEEECCCEEEEEECCCEEEEECC
>Mature Secondary Structure 
ANVNIKPLEDRVLVQISEAETTTASGLVIPDSAKEKPQEGVVVAAGPGRFDGDDRVPMD
CCCCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCCCEE
IKEGDTVVFSKYGGTELKYNGEEYLLLNARDVLAIIEK
ECCCCEEEEECCCCEEEEECCCEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910