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The map label for this gene is alr [H]

Identifier: 38233177

GI number: 38233177

Start: 536812

End: 537960

Strand: Direct

Name: alr [H]

Synonym: DIP0568

Alternate gene names: 38233177

Gene position: 536812-537960 (Clockwise)

Preceding gene: 38233175

Following gene: 38233178

Centisome position: 21.57

GC content: 55.87

Gene sequence:

>1149_bases
ATGAACCTGCTCGAAACTCGCATCTCGTGCGACGCCATTGCTGCGAACACGCGACGTTTAAAAGACATGGTTGCTCCCGC
TCAGCTCATGTGTGTTGTAAAAGCTGACGGCTACAATCACGGTGCCCCAGAAGTTGCTACTGTGATGGCGCGTAACGGTG
CCGACCAATTTGGTGTCGCAACGCTTGCGGAAGCACATCAGCTACGAGACGCGGGTATCACTCTCCCCATCCTGTGCTGG
ATCTGGTCACCCGAGCAGGACTTTTCCGCCGCCATTGACCGTGACATCGACTTAGCCGCCGTCAGCATGGATCACGTTCG
TGCACTGATCGCAGAGGCTATGCGTCGTCCCGCAGGTACCCGAGTGCGGGTGACCGTGAAAATTGACACGGAACTTCACC
GATCTGGAATTGACGAAGCAAACTGGACAGAAGCCTTTGAGCTTCTTCATGCTTGCCCCCAAGTCAACGTCACGGGCGTA
TTTAGTCACTTGGCATGCGCAGACGACTTGGAATCGGACTACACCGACCACCAAGCAGAGGTATTTCGCAGGGCGATTTC
CGCAGGTAGAAACGTAGGCCTAGACCTTCCTGTTAATCATCTAGCGGCATCGCCAGCAACACTAACCCGCCCCGACTTGC
ACTTTGACATGGTCCGACCTGGGCTTGCCCTCTATGGTCACGAACCGATAGCAGGGCTCGACCATGGGCTGCGCGAAGCC
ATGACATGGATTGGTTCAGTAACAGTGGTCAAACCCATCGCGGCAGGCCAAGGAACCAGCTACAACATGACATGGCATGC
GCCCGCAGATGGCTACCTCTGCGTGGTGCCGGTGGGCTATGCGGACGGATTACCGCGCAACGTACAAGGACATTTAGAAG
TAACGATCGCCGGCACGCGCTACCCACAAGTAGGGCGCGTTTGTATGGACCAGATTGTGGTATTCCTTGGCGATAATTCC
CGCGGTGTTGCCCCTGGTGATGAGGCAATTATTTTTGGTCCAAGAGATACCCAAGCGATGACCGTCACGGAGCTGGCCTG
CGCTACGGGAACCATCAACTATGAAATCTTGTGCCGCCCGACCGGACGAAGCCATAGAACCTATAGTGCTCTTGACGCCG
TTGCGCCCACGCACCCTACTGAAAGCTGA

Upstream 100 bases:

>100_bases
GAATTCTTGCCACGTGGCCGGTGCAGTTGTGAGGAAAACCGGAAAGAAAAAGGGGGAGCCGCTGCAGCATGAAAAGACAG
CAGTGGCATGATAGGACGTT

Downstream 100 bases:

>100_bases
TACCCCATGGATACCACCTTTGCTCGTAGCGGAAACATACGACTCGAAACCGCCGCAGAAACCCAAGCCTTCGCCGAAGA
ACTTGGTCGTCATCTCGAAG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MNLLETRISCDAIAANTRRLKDMVAPAQLMCVVKADGYNHGAPEVATVMARNGADQFGVATLAEAHQLRDAGITLPILCW
IWSPEQDFSAAIDRDIDLAAVSMDHVRALIAEAMRRPAGTRVRVTVKIDTELHRSGIDEANWTEAFELLHACPQVNVTGV
FSHLACADDLESDYTDHQAEVFRRAISAGRNVGLDLPVNHLAASPATLTRPDLHFDMVRPGLALYGHEPIAGLDHGLREA
MTWIGSVTVVKPIAAGQGTSYNMTWHAPADGYLCVVPVGYADGLPRNVQGHLEVTIAGTRYPQVGRVCMDQIVVFLGDNS
RGVAPGDEAIIFGPRDTQAMTVTELACATGTINYEILCRPTGRSHRTYSALDAVAPTHPTES

Sequences:

>Translated_382_residues
MNLLETRISCDAIAANTRRLKDMVAPAQLMCVVKADGYNHGAPEVATVMARNGADQFGVATLAEAHQLRDAGITLPILCW
IWSPEQDFSAAIDRDIDLAAVSMDHVRALIAEAMRRPAGTRVRVTVKIDTELHRSGIDEANWTEAFELLHACPQVNVTGV
FSHLACADDLESDYTDHQAEVFRRAISAGRNVGLDLPVNHLAASPATLTRPDLHFDMVRPGLALYGHEPIAGLDHGLREA
MTWIGSVTVVKPIAAGQGTSYNMTWHAPADGYLCVVPVGYADGLPRNVQGHLEVTIAGTRYPQVGRVCMDQIVVFLGDNS
RGVAPGDEAIIFGPRDTQAMTVTELACATGTINYEILCRPTGRSHRTYSALDAVAPTHPTES
>Mature_382_residues
MNLLETRISCDAIAANTRRLKDMVAPAQLMCVVKADGYNHGAPEVATVMARNGADQFGVATLAEAHQLRDAGITLPILCW
IWSPEQDFSAAIDRDIDLAAVSMDHVRALIAEAMRRPAGTRVRVTVKIDTELHRSGIDEANWTEAFELLHACPQVNVTGV
FSHLACADDLESDYTDHQAEVFRRAISAGRNVGLDLPVNHLAASPATLTRPDLHFDMVRPGLALYGHEPIAGLDHGLREA
MTWIGSVTVVKPIAAGQGTSYNMTWHAPADGYLCVVPVGYADGLPRNVQGHLEVTIAGTRYPQVGRVCMDQIVVFLGDNS
RGVAPGDEAIIFGPRDTQAMTVTELACATGTINYEILCRPTGRSHRTYSALDAVAPTHPTES

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=367, Percent_Identity=32.1525885558583, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1787439, Length=362, Percent_Identity=27.0718232044199, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41235; Mature: 41235

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00024 HEMOPEXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLETRISCDAIAANTRRLKDMVAPAQLMCVVKADGYNHGAPEVATVMARNGADQFGVA
CCHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCHHHHH
TLAEAHQLRDAGITLPILCWIWSPEQDFSAAIDRDIDLAAVSMDHVRALIAEAMRRPAGT
HHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCC
RVRVTVKIDTELHRSGIDEANWTEAFELLHACPQVNVTGVFSHLACADDLESDYTDHQAE
EEEEEEEECCHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
VFRRAISAGRNVGLDLPVNHLAASPATLTRPDLHFDMVRPGLALYGHEPIAGLDHGLREA
HHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHCCCEEEECCCCCHHHHHHHHHH
MTWIGSVTVVKPIAAGQGTSYNMTWHAPADGYLCVVPVGYADGLPRNVQGHLEVTIAGTR
HHHHCCCEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCC
YPQVGRVCMDQIVVFLGDNSRGVAPGDEAIIFGPRDTQAMTVTELACATGTINYEILCRP
CCHHHHHHHHCEEEEECCCCCCCCCCCCEEEECCCCCCEEEHHHHHHHCCCEEEEEEEEC
TGRSHRTYSALDAVAPTHPTES
CCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNLLETRISCDAIAANTRRLKDMVAPAQLMCVVKADGYNHGAPEVATVMARNGADQFGVA
CCHHHHHCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCHHHHH
TLAEAHQLRDAGITLPILCWIWSPEQDFSAAIDRDIDLAAVSMDHVRALIAEAMRRPAGT
HHHHHHHHHHCCCEEEEEEEEECCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCC
RVRVTVKIDTELHRSGIDEANWTEAFELLHACPQVNVTGVFSHLACADDLESDYTDHQAE
EEEEEEEECCHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
VFRRAISAGRNVGLDLPVNHLAASPATLTRPDLHFDMVRPGLALYGHEPIAGLDHGLREA
HHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHCCCEEEECCCCCHHHHHHHHHH
MTWIGSVTVVKPIAAGQGTSYNMTWHAPADGYLCVVPVGYADGLPRNVQGHLEVTIAGTR
HHHHCCCEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCC
YPQVGRVCMDQIVVFLGDNSRGVAPGDEAIIFGPRDTQAMTVTELACATGTINYEILCRP
CCHHHHHHHHCEEEEECCCCCCCCCCCCEEEECCCCCCEEEHHHHHHHCCCEEEEEEEEC
TGRSHRTYSALDAVAPTHPTES
CCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]