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The map label for this gene is nagA [H]

Identifier: 38233129

GI number: 38233129

Start: 488618

End: 489754

Strand: Direct

Name: nagA [H]

Synonym: DIP0520

Alternate gene names: 38233129

Gene position: 488618-489754 (Clockwise)

Preceding gene: 38233128

Following gene: 38233130

Centisome position: 19.63

GC content: 59.37

Gene sequence:

>1137_bases
ATGAAACAGATCATTGGTGACCTGGTCACTCCAGCCGGTGTTCTACCGCACCATCGGATAGACATCGACTCTAACGGAAT
GATCGCAGCGATCACACCAGCACCAGAAGTAGATAACCCACCCCTCGTGCTGCCAGGTCTTGCCGACATCCACAATCACG
GTGGAGCAGGGGAGTCCTTCCCCAACTCCGACTACGACGGATGCGTGATCGCCGCACGCCACCACCGCGCACATGGCTCG
ACCACGCTGCTGGCGTCGACAGTATCCATGCCCGAGCACACCCTACTGCCGCAACTATCCCTCCTAGCGGATCTTGCCGA
CGCCGGTGAAATCGACGGAATCCACGCCGAAGGCCCCTTTGTTAACCCGTGCCGCTGCGGCGCACAAGACCCAGAAGCGA
TCATCCTAGGCGACCCAGAACTGTTCAAGAAAATGATCAGAGCGGCACGCGGCTGGCTCAAATCCATGACCTTCGCCCCC
GAAACCGCACACGCCAAGGAAATCATCGACCTCTGCGCCGAAAACAACATCATCGTCTCCCTCGGACACACCGACGCAGA
CTTCTCAGTCACCGAACAAGCCCTGTCCTACGCAGTAGCAGCCGGTGCAACTGTGACCGCAACGCACCTATTTAATGCAA
TGCCAGCAATACACCACCGTGACCCCGGTGCAGCCGCAGCGCTTATCGACGCCGCAGCTCGAGGCAACGCCCACGTAGAA
CTAGTCGCCGATGGCATCCACCTCGATGACCACACAGTGCGCATGGTCATCGACTCCGTAGGTGCGGATCGAGTGAGCTT
TGTCTCCGACGCGATGGGCGCAGCAGGAAAAGAAGACGGGGACTACGTTCTCGGAGCCCTCGCCGTCACCGTGAAAGACT
CCGTCGCACGACTGACCACCACCGACGGCAGCGAAGGCGCTATCGCAGGCGGCACCTCACGTGTGATCGACCAAGTACGC
CGACACGTCGCCGCAGGATTCCCCATAGAAGACGTAGTCAAAGCCGCAACCGAAGGAACCCGAATCCTCGGATTACACGA
CCGCGGGGCCATCGAAGTAGGAAAACGCGCAGACCTTGTCCTATGCAGCGGCGACTTCCATGTCGACCACGTGCTCATCA
AAGGCGAGGACATCTAA

Upstream 100 bases:

>100_bases
GCACCGCGATCACCGACACTGCGTGGGTTACCACCCAGTTTGCCAACGCAGCCCGCGGAAACTAACACCCCCACACATCA
CAACCAAGGAGTACCAAGGA

Downstream 100 bases:

>100_bases
GGCCACAAGCCTCCTCAAAGGAAAGAGAAAACCATGGAGATCGTAATCACCCCCACCAAGGACGACGCCGCTCGTATCGC
CGCCGACATCCTAGAAGAAT

Product: putative deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MKQIIGDLVTPAGVLPHHRIDIDSNGMIAAITPAPEVDNPPLVLPGLADIHNHGGAGESFPNSDYDGCVIAARHHRAHGS
TTLLASTVSMPEHTLLPQLSLLADLADAGEIDGIHAEGPFVNPCRCGAQDPEAIILGDPELFKKMIRAARGWLKSMTFAP
ETAHAKEIIDLCAENNIIVSLGHTDADFSVTEQALSYAVAAGATVTATHLFNAMPAIHHRDPGAAAALIDAAARGNAHVE
LVADGIHLDDHTVRMVIDSVGADRVSFVSDAMGAAGKEDGDYVLGALAVTVKDSVARLTTTDGSEGAIAGGTSRVIDQVR
RHVAAGFPIEDVVKAATEGTRILGLHDRGAIEVGKRADLVLCSGDFHVDHVLIKGEDI

Sequences:

>Translated_378_residues
MKQIIGDLVTPAGVLPHHRIDIDSNGMIAAITPAPEVDNPPLVLPGLADIHNHGGAGESFPNSDYDGCVIAARHHRAHGS
TTLLASTVSMPEHTLLPQLSLLADLADAGEIDGIHAEGPFVNPCRCGAQDPEAIILGDPELFKKMIRAARGWLKSMTFAP
ETAHAKEIIDLCAENNIIVSLGHTDADFSVTEQALSYAVAAGATVTATHLFNAMPAIHHRDPGAAAALIDAAARGNAHVE
LVADGIHLDDHTVRMVIDSVGADRVSFVSDAMGAAGKEDGDYVLGALAVTVKDSVARLTTTDGSEGAIAGGTSRVIDQVR
RHVAAGFPIEDVVKAATEGTRILGLHDRGAIEVGKRADLVLCSGDFHVDHVLIKGEDI
>Mature_378_residues
MKQIIGDLVTPAGVLPHHRIDIDSNGMIAAITPAPEVDNPPLVLPGLADIHNHGGAGESFPNSDYDGCVIAARHHRAHGS
TTLLASTVSMPEHTLLPQLSLLADLADAGEIDGIHAEGPFVNPCRCGAQDPEAIILGDPELFKKMIRAARGWLKSMTFAP
ETAHAKEIIDLCAENNIIVSLGHTDADFSVTEQALSYAVAAGATVTATHLFNAMPAIHHRDPGAAAALIDAAARGNAHVE
LVADGIHLDDHTVRMVIDSVGADRVSFVSDAMGAAGKEDGDYVLGALAVTVKDSVARLTTTDGSEGAIAGGTSRVIDQVR
RHVAAGFPIEDVVKAATEGTRILGLHDRGAIEVGKRADLVLCSGDFHVDHVLIKGEDI

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=376, Percent_Identity=28.9893617021277, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI224922791, Length=375, Percent_Identity=28.8, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI1786892, Length=390, Percent_Identity=25.1282051282051, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17553768, Length=363, Percent_Identity=30.8539944903581, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI19920392, Length=344, Percent_Identity=31.6860465116279, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI281361140, Length=358, Percent_Identity=30.4469273743017, Blast_Score=112, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 39457; Mature: 39457

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIIGDLVTPAGVLPHHRIDIDSNGMIAAITPAPEVDNPPLVLPGLADIHNHGGAGESF
CHHHHHHHCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCEEECCHHHHHCCCCCCCCC
PNSDYDGCVIAARHHRAHGSTTLLASTVSMPEHTLLPQLSLLADLADAGEIDGIHAEGPF
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCC
VNPCRCGAQDPEAIILGDPELFKKMIRAARGWLKSMTFAPETAHAKEIIDLCAENNIIVS
CCHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEE
LGHTDADFSVTEQALSYAVAAGATVTATHLFNAMPAIHHRDPGAAAALIDAAARGNAHVE
ECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCCCCEEE
LVADGIHLDDHTVRMVIDSVGADRVSFVSDAMGAAGKEDGDYVLGALAVTVKDSVARLTT
EEECCEEECCCHHEEHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEEEHHHHEEEEE
TDGSEGAIAGGTSRVIDQVRRHVAAGFPIEDVVKAATEGTRILGLHDRGAIEVGKRADLV
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCEEECCCCCEE
LCSGDFHVDHVLIKGEDI
EECCCCEEEEEEEECCCC
>Mature Secondary Structure
MKQIIGDLVTPAGVLPHHRIDIDSNGMIAAITPAPEVDNPPLVLPGLADIHNHGGAGESF
CHHHHHHHCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCEEECCHHHHHCCCCCCCCC
PNSDYDGCVIAARHHRAHGSTTLLASTVSMPEHTLLPQLSLLADLADAGEIDGIHAEGPF
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEECCCCC
VNPCRCGAQDPEAIILGDPELFKKMIRAARGWLKSMTFAPETAHAKEIIDLCAENNIIVS
CCHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEE
LGHTDADFSVTEQALSYAVAAGATVTATHLFNAMPAIHHRDPGAAAALIDAAARGNAHVE
ECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHCCCCCHHHHHHHHHHCCCCEEE
LVADGIHLDDHTVRMVIDSVGADRVSFVSDAMGAAGKEDGDYVLGALAVTVKDSVARLTT
EEECCEEECCCHHEEHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEEEHHHHEEEEE
TDGSEGAIAGGTSRVIDQVRRHVAAGFPIEDVVKAATEGTRILGLHDRGAIEVGKRADLV
CCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCEEECCCCCEE
LCSGDFHVDHVLIKGEDI
EECCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]