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The map label for this gene is nanE [H]

Identifier: 38233128

GI number: 38233128

Start: 487887

End: 488582

Strand: Direct

Name: nanE [H]

Synonym: DIP0519

Alternate gene names: 38233128

Gene position: 487887-488582 (Clockwise)

Preceding gene: 38233127

Following gene: 38233129

Centisome position: 19.6

GC content: 59.48

Gene sequence:

>696_bases
ATGGACCGTAACGAATTTATCGACCAAGTACGTGGCAGCCTGATCGTCTCAGCACAAGCCCCAACAGGGCACCCACTGCG
CGACACCCGCACCATCGCCTTCCTTGCAAAAGCTGCAGAATACGGTGGATCCACCGCCATTCGCTGCGGCGGCTACGGCG
GACTCGACGACATCGCCGCAGTACGCGAAGCCGTATCCCTGCCTGTCATTGGCCTTACCAAAGAAGGCGACACCGGCGTG
TACATCACTCCCACCGTTGCCTCCGCGGTAGCAGTAGCACAAGCAGGCGCAGAAGTAGTTGCTATCGACGCCACCCTGCG
CCCCCGCCAAGACGGATCCACCTTCAAAGAACAAGTAGATGCCGTTCATGCCGAAGGAAAACTCGCCATGGCTGACATCG
CTACCGCCGAAGAAGCCGTCCAAGCACACCGCGACGGTGCCGACATCATTTCCACCACATTGGCCGGATACACCGAGCAC
CGCGAAAAGACTCACGGCCCCGACATCGAGCTCATCAAGGAAATACGCGAGCTCCTAGGCGATGAGATCTTCCTGATCGG
CGAAGGCCGCTTCCACAGCCCAGAGCACGTCAAGCAGGGATTCGCTGCAGGTATCGATGCCGTTATCGTCGGCACCGCGA
TCACCGACACTGCGTGGGTTACCACCCAGTTTGCCAACGCAGCCCGCGGAAACTAA

Upstream 100 bases:

>100_bases
CGGCAAGCACAACTTGGCACCGACGCACCGATCGTCGGCGCAGCACACCTTGGCCACAGCGCCATCGAATAACACGCAAT
AACTATTGAAGGAGAAAACC

Downstream 100 bases:

>100_bases
CACCCCCACACATCACAACCAAGGAGTACCAAGGAATGAAACAGATCATTGGTGACCTGGTCACTCCAGCCGGTGTTCTA
CCGCACCATCGGATAGACAT

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MDRNEFIDQVRGSLIVSAQAPTGHPLRDTRTIAFLAKAAEYGGSTAIRCGGYGGLDDIAAVREAVSLPVIGLTKEGDTGV
YITPTVASAVAVAQAGAEVVAIDATLRPRQDGSTFKEQVDAVHAEGKLAMADIATAEEAVQAHRDGADIISTTLAGYTEH
REKTHGPDIELIKEIRELLGDEIFLIGEGRFHSPEHVKQGFAAGIDAVIVGTAITDTAWVTTQFANAARGN

Sequences:

>Translated_231_residues
MDRNEFIDQVRGSLIVSAQAPTGHPLRDTRTIAFLAKAAEYGGSTAIRCGGYGGLDDIAAVREAVSLPVIGLTKEGDTGV
YITPTVASAVAVAQAGAEVVAIDATLRPRQDGSTFKEQVDAVHAEGKLAMADIATAEEAVQAHRDGADIISTTLAGYTEH
REKTHGPDIELIKEIRELLGDEIFLIGEGRFHSPEHVKQGFAAGIDAVIVGTAITDTAWVTTQFANAARGN
>Mature_231_residues
MDRNEFIDQVRGSLIVSAQAPTGHPLRDTRTIAFLAKAAEYGGSTAIRCGGYGGLDDIAAVREAVSLPVIGLTKEGDTGV
YITPTVASAVAVAQAGAEVVAIDATLRPRQDGSTFKEQVDAVHAEGKLAMADIATAEEAVQAHRDGADIISTTLAGYTEH
REKTHGPDIELIKEIRELLGDEIFLIGEGRFHSPEHVKQGFAAGIDAVIVGTAITDTAWVTTQFANAARGN

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential) [H]

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family [H]

Homologues:

Organism=Escherichia coli, GI1789617, Length=221, Percent_Identity=36.6515837104072, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060 [H]

Pfam domain/function: PF04131 NanE [H]

EC number: =5.1.3.9 [H]

Molecular weight: Translated: 24276; Mature: 24276

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRNEFIDQVRGSLIVSAQAPTGHPLRDTRTIAFLAKAAEYGGSTAIRCGGYGGLDDIAA
CCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHH
VREAVSLPVIGLTKEGDTGVYITPTVASAVAVAQAGAEVVAIDATLRPRQDGSTFKEQVD
HHHHHCCCEEEEECCCCCCEEECCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHH
AVHAEGKLAMADIATAEEAVQAHRDGADIISTTLAGYTEHREKTHGPDIELIKEIRELLG
HHHCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
DEIFLIGEGRFHSPEHVKQGFAAGIDAVIVGTAITDTAWVTTQFANAARGN
CCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MDRNEFIDQVRGSLIVSAQAPTGHPLRDTRTIAFLAKAAEYGGSTAIRCGGYGGLDDIAA
CCHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHH
VREAVSLPVIGLTKEGDTGVYITPTVASAVAVAQAGAEVVAIDATLRPRQDGSTFKEQVD
HHHHHCCCEEEEECCCCCCEEECCHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHH
AVHAEGKLAMADIATAEEAVQAHRDGADIISTTLAGYTEHREKTHGPDIELIKEIRELLG
HHHCCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCC
DEIFLIGEGRFHSPEHVKQGFAAGIDAVIVGTAITDTAWVTTQFANAARGN
CCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA