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The map label for this gene is dapA [H]

Identifier: 38233120

GI number: 38233120

Start: 479270

End: 480190

Strand: Reverse

Name: dapA [H]

Synonym: DIP0511

Alternate gene names: 38233120

Gene position: 480190-479270 (Counterclockwise)

Preceding gene: 38233121

Following gene: 38233119

Centisome position: 19.3

GC content: 59.28

Gene sequence:

>921_bases
ATGCCTTCCATCGTTAAGGGCATCATCCCACCAGTACTCACCCCCATGAAGTCCGATCGCAGCATCGATTTCGAAGCTCT
CGAGCGCCTCGTTGAGCACCTCATTGCTGGTGGTGTTGACGGCCTGTTCGCTCTGGGTTCTTCCGGCGAGGTTGCCTTCT
TGTCTGACGAAGACCGCGCAACCGTCATCCGCGAAATTGTCCGTATCGCAGCTGGTCGTGTGCCTGTCTACGCCGGTGTG
ATCGATATGCAGGTCAACCGCATGCTCGGCCACATCAAGGCTGCTGAAGAAGCAGGTGTAGACGCCATCGTTGCCACCGC
CCCCTTCTACGCCATCTGCGGACCTGCAGAGGTAGAGGCTCACTTCCGCGCGGTAGCTGCAGCAACGTCTCTTCCTGTCA
TCGCTTACGACATCCCAGTGTGCGTACACACTAAGCTCTCCCCTGAGCTGCTGGTCAAGTTGGGCTCTGAGGGGGTTCTG
GCAGGCGTTAAGGATTCCTCTGGCGACGACGTCTCCTTCCGCCGCCTTGTCATGCTGAACAAGAAGGCAGGCTCCCCGCT
AACCCTGCTCACCGGCCACGAGGCAGTAGTCGACGGCGCATTCATCGCAGGTGCCGACGGCTGTGTCCCAGGTCTTGGCA
ACGTCGATCCCGCCGGCTACGTCCGCATGTGGAAGGCTGCAGAGGCCGGCGACTGGGCTACCGTCCAGAAGGAACAAGAT
CGCCTCGCTGCCCTGTTCGAGATCGTCTTCCAGCCCATCGGCAAGGTTGGCCCAGCAGCAGGTGTCGGTTCTTTCAAGAC
CGCCCTCGAGCTCATGGGTATTTTCTCCTCCAACCTGATGTCCATGCCATTGGCACCTATCGACGACGCCCCATCCCGCG
ATGCAATCGCTGAAATTCTGAAGGCCACTGATATGCTCTAA

Upstream 100 bases:

>100_bases
GCTCTTTGCCGCCCCTAAGACGGATTACACTCGCACGTTGCTCGCAGCTACCCCGTCATTCCTTTAAAACTTACGCTTTT
TTGAAAGGATTTTTCCTATC

Downstream 100 bases:

>100_bases
AGCCTTTGAGGCTTTACCCTCAAACCCCTTCCCAATCCCTTCCCACAGAAAACCGAAAATCCGCTAGAACTGCACTGTTG
CTCAAACTAAGTTGTGTCTA

Product: putative lysine biosynthesis protein

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MPSIVKGIIPPVLTPMKSDRSIDFEALERLVEHLIAGGVDGLFALGSSGEVAFLSDEDRATVIREIVRIAAGRVPVYAGV
IDMQVNRMLGHIKAAEEAGVDAIVATAPFYAICGPAEVEAHFRAVAAATSLPVIAYDIPVCVHTKLSPELLVKLGSEGVL
AGVKDSSGDDVSFRRLVMLNKKAGSPLTLLTGHEAVVDGAFIAGADGCVPGLGNVDPAGYVRMWKAAEAGDWATVQKEQD
RLAALFEIVFQPIGKVGPAAGVGSFKTALELMGIFSSNLMSMPLAPIDDAPSRDAIAEILKATDML

Sequences:

>Translated_306_residues
MPSIVKGIIPPVLTPMKSDRSIDFEALERLVEHLIAGGVDGLFALGSSGEVAFLSDEDRATVIREIVRIAAGRVPVYAGV
IDMQVNRMLGHIKAAEEAGVDAIVATAPFYAICGPAEVEAHFRAVAAATSLPVIAYDIPVCVHTKLSPELLVKLGSEGVL
AGVKDSSGDDVSFRRLVMLNKKAGSPLTLLTGHEAVVDGAFIAGADGCVPGLGNVDPAGYVRMWKAAEAGDWATVQKEQD
RLAALFEIVFQPIGKVGPAAGVGSFKTALELMGIFSSNLMSMPLAPIDDAPSRDAIAEILKATDML
>Mature_305_residues
PSIVKGIIPPVLTPMKSDRSIDFEALERLVEHLIAGGVDGLFALGSSGEVAFLSDEDRATVIREIVRIAAGRVPVYAGVI
DMQVNRMLGHIKAAEEAGVDAIVATAPFYAICGPAEVEAHFRAVAAATSLPVIAYDIPVCVHTKLSPELLVKLGSEGVLA
GVKDSSGDDVSFRRLVMLNKKAGSPLTLLTGHEAVVDGAFIAGADGCVPGLGNVDPAGYVRMWKAAEAGDWATVQKEQDR
LAALFEIVFQPIGKVGPAAGVGSFKTALELMGIFSSNLMSMPLAPIDDAPSRDAIAEILKATDML

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=273, Percent_Identity=24.9084249084249, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI13540533, Length=312, Percent_Identity=25.6410256410256, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87082415, Length=246, Percent_Identity=28.8617886178862, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1786463, Length=232, Percent_Identity=32.3275862068966, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789620, Length=305, Percent_Identity=28.1967213114754, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788823, Length=303, Percent_Identity=24.4224422442244, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32015; Mature: 31884

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSIVKGIIPPVLTPMKSDRSIDFEALERLVEHLIAGGVDGLFALGSSGEVAFLSDEDRA
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHEEECCCCCEEEECCCCHH
TVIREIVRIAAGRVPVYAGVIDMQVNRMLGHIKAAEEAGVDAIVATAPFYAICGPAEVEA
HHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHEECCCHHHHH
HFRAVAAATSLPVIAYDIPVCVHTKLSPELLVKLGSEGVLAGVKDSSGDDVSFRRLVMLN
HHHHHHHHHCCCEEEEECCEEEECCCCHHHHHHCCCCCCEEECCCCCCCCHHEEEEEEEE
KKAGSPLTLLTGHEAVVDGAFIAGADGCVPGLGNVDPAGYVRMWKAAEAGDWATVQKEQD
CCCCCCEEEEECCHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHH
RLAALFEIVFQPIGKVGPAAGVGSFKTALELMGIFSSNLMSMPLAPIDDAPSRDAIAEIL
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
KATDML
HHHCCC
>Mature Secondary Structure 
PSIVKGIIPPVLTPMKSDRSIDFEALERLVEHLIAGGVDGLFALGSSGEVAFLSDEDRA
CCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHEEECCCCCEEEECCCCHH
TVIREIVRIAAGRVPVYAGVIDMQVNRMLGHIKAAEEAGVDAIVATAPFYAICGPAEVEA
HHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHEECCCHHHHH
HFRAVAAATSLPVIAYDIPVCVHTKLSPELLVKLGSEGVLAGVKDSSGDDVSFRRLVMLN
HHHHHHHHHCCCEEEEECCEEEECCCCHHHHHHCCCCCCEEECCCCCCCCHHEEEEEEEE
KKAGSPLTLLTGHEAVVDGAFIAGADGCVPGLGNVDPAGYVRMWKAAEAGDWATVQKEQD
CCCCCCEEEEECCHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHHH
RLAALFEIVFQPIGKVGPAAGVGSFKTALELMGIFSSNLMSMPLAPIDDAPSRDAIAEIL
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
KATDML
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA