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The map label for this gene is moaC [H]

Identifier: 38233117

GI number: 38233117

Start: 474674

End: 475141

Strand: Reverse

Name: moaC [H]

Synonym: DIP0505

Alternate gene names: 38233117

Gene position: 475141-474674 (Counterclockwise)

Preceding gene: 38233118

Following gene: 38233116

Centisome position: 19.09

GC content: 51.92

Gene sequence:

>468_bases
ATGTTTACACATCTTAATAACAACGGTTCCGCCTACATGGTGGATGTAACGCATAAGCAAGTATCGGTGCGCAGCGCTAC
CGCGGTAGGTGAAGTGATATGTTCACCTACCGTGCTTGAAGCATTGACCAATGGCACTGTACCTAAAGGTGATGTTGTGG
CATGTGCTCGTATCGCGGGCATCTCTGCCGCTAAGAAAGTGCCTGATTTGCTGCCCTTGGCGCATACGATTGGCGTGCAC
GGTTGCGAAGTCATCATTGAGATCGCAGATGATCGTGTACGCCTTAAGGCTACTGTCCGCACCGCAGATCGAACAGGCGT
GGAGATGGAAGCCCTTACCGCAGTCAGTGTTGCCGCTTTAACCATCATTGACATGGTTAAAGGCGTCGACCGCAGTGCAT
ATATCAGCAGGTGTGGCATTGTTGCCAAGTCGGGAGGCCGCTCAGGTGATTGGTCCCGAGAATTGTAA

Upstream 100 bases:

>100_bases
CTCACTGGTGGGGGTTAATGCGCTCATTCATGTGCCAGCCGACGCCCACCGCGTAGCGCCTCGTGTTATCCCTCTAACTT
TTTAATCAAGGACTTTTATT

Downstream 100 bases:

>100_bases
TTCCGTATCCGAGCCCATCGCCTATGTCATCATTCTTGCCGGTGGGCGCAGTAGTCGCATGGGATACGATAAAGCTCAGG
TGATGGTAGATGGGCGCCGA

Product: molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MFTHLNNNGSAYMVDVTHKQVSVRSATAVGEVICSPTVLEALTNGTVPKGDVVACARIAGISAAKKVPDLLPLAHTIGVH
GCEVIIEIADDRVRLKATVRTADRTGVEMEALTAVSVAALTIIDMVKGVDRSAYISRCGIVAKSGGRSGDWSREL

Sequences:

>Translated_155_residues
MFTHLNNNGSAYMVDVTHKQVSVRSATAVGEVICSPTVLEALTNGTVPKGDVVACARIAGISAAKKVPDLLPLAHTIGVH
GCEVIIEIADDRVRLKATVRTADRTGVEMEALTAVSVAALTIIDMVKGVDRSAYISRCGIVAKSGGRSGDWSREL
>Mature_155_residues
MFTHLNNNGSAYMVDVTHKQVSVRSATAVGEVICSPTVLEALTNGTVPKGDVVACARIAGISAAKKVPDLLPLAHTIGVH
GCEVIIEIADDRVRLKATVRTADRTGVEMEALTAVSVAALTIIDMVKGVDRSAYISRCGIVAKSGGRSGDWSREL

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=155, Percent_Identity=47.741935483871, Blast_Score=124, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32566331, Length=150, Percent_Identity=38, Blast_Score=113, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28574490, Length=155, Percent_Identity=43.2258064516129, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28574492, Length=144, Percent_Identity=43.75, Blast_Score=102, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16257; Mature: 16257

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTHLNNNGSAYMVDVTHKQVSVRSATAVGEVICSPTVLEALTNGTVPKGDVVACARIAG
CCEEECCCCCEEEEEECCCEEHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHC
ISAAKKVPDLLPLAHTIGVHGCEVIIEIADDRVRLKATVRTADRTGVEMEALTAVSVAAL
CHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHH
TIIDMVKGVDRSAYISRCGIVAKSGGRSGDWSREL
HHHHHHHCCCHHHHHHHCCEEECCCCCCCCCCCCC
>Mature Secondary Structure
MFTHLNNNGSAYMVDVTHKQVSVRSATAVGEVICSPTVLEALTNGTVPKGDVVACARIAG
CCEEECCCCCEEEEEECCCEEHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHC
ISAAKKVPDLLPLAHTIGVHGCEVIIEIADDRVRLKATVRTADRTGVEMEALTAVSVAAL
CHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCEEEEEEEEECCCCCCCHHHHHHHHHHHH
TIIDMVKGVDRSAYISRCGIVAKSGGRSGDWSREL
HHHHHHHCCCHHHHHHHCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA