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The map label for this gene is 38233042

Identifier: 38233042

GI number: 38233042

Start: 392451

End: 393653

Strand: Reverse

Name: 38233042

Synonym: DIP0428

Alternate gene names: NA

Gene position: 393653-392451 (Counterclockwise)

Preceding gene: 38233048

Following gene: 38233041

Centisome position: 15.82

GC content: 59.52

Gene sequence:

>1203_bases
ATGGGGCACGTGAGTAATTCCCCTTTTTCGGTTGATGTTCTGGTGGTCGGCGGTGGCCCAGCCGGCTCGGCGGCGGCTAT
CCATGCAGCTAAAGCAGGTTATTCGGTATTGCTTATCGACGCCCAGCCCTTCCCCCGCGACAAGACCTGCGGAGATGGCT
TAACGCCTCGCGCAGTACATCAACTAGAGGCACTTGGGGTGGATGTGACCTCTCGTTATCGCTCCTTCGGCCTGAAACTG
CATGGTTTTGGCGGTTCGGTCACCGTCCCATGGCCCGAATCACACTTTGGCCAAGTAAGCTCCGCGATGCCGCGCATGAA
ATTCGATGCCATGTTGTGGGAAATGGCAGCACAGCACGCAACGACGTGGACGGCTACTGCCTCTGAAGTAGAGATTGATT
CCGCGATTCGCAGTGTCACCATGTCCGATGGGCGCGTCGTTAAGCCGCGAAGCGTCATCGTGGCCGATGGTGTCCGTTCC
ACGTTTGGAAAACTGCTGGGACGCACATGGCACCGCGGCGAGGTGTACGGTATCGCGGCGCGCTCCTATTGCACCACACC
ACGCAGCACTGAGCCATGGATGCATTCGCACCTCGAGCTTCGCGACGACTCCACCACCTTGCCCGGCTACGGATGGATCT
TCCCGATTGGCGACGGCACCGCCAATGTGGGTTGCGGCGCACTGTCCACCGATAAGCGCCCAGCGAAAATCAATACCAAG
AAACTGTTGCGTCACTACGCCAGCCAGCAGACAGACTGGGAATTTGGCACCCCCCAACGGGTGGCTTCAGCATTATTACC
CATGGGCGGCGCAGTCAGCACCATCGCAGGACCTAACTGGATGCTCATCGGCGATGCTGCCGCTTGCGTGAACCCTCTCA
ACGGTGAAGGCATCGACTACGGCCTCGAAACCGCAGCCCTGGCCGTAGCTCACCTTGATAACCCCTTGGAGTGGCCACAC
ATTTTGCGAGAAACCTATGGTGAGGCGTTCCTCTTGGCGCGCACCGCAGCACGCCTACTCACCTACCCCCAGTTCCTTCC
GCTCACCGGACCTATTGCCTTGCGCACCCCGTTGATGGCTTCTGCGGCACGACTCATGGGTAACTTGGTCACCGAGGAAG
ACAAAGACATCGTGGCCCGCGCGTGGCGAGCAGCCGGTTGGGGTGTGACAAAAATCCGTGGCGGGTCCCCACTGTGGGAC
TAA

Upstream 100 bases:

>100_bases
CTCGCGTACCGTTGCCCATTCCTCAACTACCTTTGTCTCGTGTTCAGCTAACCCCCTAACCGTAGTCGAAATACTCGTAC
TTCTACACATACATGCCACA

Downstream 100 bases:

>100_bases
GCTCGATGGCATGAACAAGCTAGTAGTGATAGGCCTCGGCCATGTGGGTTCATACGTACTGAGCTACGCCATGGCATCGG
GGTTGTATGCAGAAATTGCC

Product: putative FAD-linked oxidoreductase

Products: NA

Alternate protein names: DGGGPL reductase 1; 2,3-di-O-geranylgeranylglyceryl phosphate reductase 1; Geranylgeranyl reductase 1; GGR 1 [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MGHVSNSPFSVDVLVVGGGPAGSAAAIHAAKAGYSVLLIDAQPFPRDKTCGDGLTPRAVHQLEALGVDVTSRYRSFGLKL
HGFGGSVTVPWPESHFGQVSSAMPRMKFDAMLWEMAAQHATTWTATASEVEIDSAIRSVTMSDGRVVKPRSVIVADGVRS
TFGKLLGRTWHRGEVYGIAARSYCTTPRSTEPWMHSHLELRDDSTTLPGYGWIFPIGDGTANVGCGALSTDKRPAKINTK
KLLRHYASQQTDWEFGTPQRVASALLPMGGAVSTIAGPNWMLIGDAAACVNPLNGEGIDYGLETAALAVAHLDNPLEWPH
ILRETYGEAFLLARTAARLLTYPQFLPLTGPIALRTPLMASAARLMGNLVTEEDKDIVARAWRAAGWGVTKIRGGSPLWD

Sequences:

>Translated_400_residues
MGHVSNSPFSVDVLVVGGGPAGSAAAIHAAKAGYSVLLIDAQPFPRDKTCGDGLTPRAVHQLEALGVDVTSRYRSFGLKL
HGFGGSVTVPWPESHFGQVSSAMPRMKFDAMLWEMAAQHATTWTATASEVEIDSAIRSVTMSDGRVVKPRSVIVADGVRS
TFGKLLGRTWHRGEVYGIAARSYCTTPRSTEPWMHSHLELRDDSTTLPGYGWIFPIGDGTANVGCGALSTDKRPAKINTK
KLLRHYASQQTDWEFGTPQRVASALLPMGGAVSTIAGPNWMLIGDAAACVNPLNGEGIDYGLETAALAVAHLDNPLEWPH
ILRETYGEAFLLARTAARLLTYPQFLPLTGPIALRTPLMASAARLMGNLVTEEDKDIVARAWRAAGWGVTKIRGGSPLWD
>Mature_399_residues
GHVSNSPFSVDVLVVGGGPAGSAAAIHAAKAGYSVLLIDAQPFPRDKTCGDGLTPRAVHQLEALGVDVTSRYRSFGLKLH
GFGGSVTVPWPESHFGQVSSAMPRMKFDAMLWEMAAQHATTWTATASEVEIDSAIRSVTMSDGRVVKPRSVIVADGVRST
FGKLLGRTWHRGEVYGIAARSYCTTPRSTEPWMHSHLELRDDSTTLPGYGWIFPIGDGTANVGCGALSTDKRPAKINTKK
LLRHYASQQTDWEFGTPQRVASALLPMGGAVSTIAGPNWMLIGDAAACVNPLNGEGIDYGLETAALAVAHLDNPLEWPHI
LRETYGEAFLLARTAARLLTYPQFLPLTGPIALRTPLMASAARLMGNLVTEEDKDIVARAWRAAGWGVTKIRGGSPLWD

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR011777
- InterPro:   IPR003042 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 42926; Mature: 42795

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHVSNSPFSVDVLVVGGGPAGSAAAIHAAKAGYSVLLIDAQPFPRDKTCGDGLTPRAVH
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHH
QLEALGVDVTSRYRSFGLKLHGFGGSVTVPWPESHFGQVSSAMPRMKFDAMLWEMAAQHA
HHHHHCCCHHHHHHHCCCEEEECCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHC
TTWTATASEVEIDSAIRSVTMSDGRVVKPRSVIVADGVRSTFGKLLGRTWHRGEVYGIAA
CEEECCCCHHHHHHHHHHEECCCCEEECCCEEEEECCHHHHHHHHHCCCCCCCCEEEEEE
RSYCTTPRSTEPWMHSHLELRDDSTTLPGYGWIFPIGDGTANVGCGALSTDKRPAKINTK
HHEECCCCCCCCHHHHCEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHH
KLLRHYASQQTDWEFGTPQRVASALLPMGGAVSTIAGPNWMLIGDAAACVNPLNGEGIDY
HHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHCCCCCEEEEECHHHHCCCCCCCCCCC
GLETAALAVAHLDNPLEWPHILRETYGEAFLLARTAARLLTYPQFLPLTGPIALRTPLMA
CHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
SAARLMGNLVTEEDKDIVARAWRAAGWGVTKIRGGSPLWD
HHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
>Mature Secondary Structure 
GHVSNSPFSVDVLVVGGGPAGSAAAIHAAKAGYSVLLIDAQPFPRDKTCGDGLTPRAVH
CCCCCCCEEEEEEEECCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHH
QLEALGVDVTSRYRSFGLKLHGFGGSVTVPWPESHFGQVSSAMPRMKFDAMLWEMAAQHA
HHHHHCCCHHHHHHHCCCEEEECCCEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHC
TTWTATASEVEIDSAIRSVTMSDGRVVKPRSVIVADGVRSTFGKLLGRTWHRGEVYGIAA
CEEECCCCHHHHHHHHHHEECCCCEEECCCEEEEECCHHHHHHHHHCCCCCCCCEEEEEE
RSYCTTPRSTEPWMHSHLELRDDSTTLPGYGWIFPIGDGTANVGCGALSTDKRPAKINTK
HHEECCCCCCCCHHHHCEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHH
KLLRHYASQQTDWEFGTPQRVASALLPMGGAVSTIAGPNWMLIGDAAACVNPLNGEGIDY
HHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCHHCCCCCEEEEECHHHHCCCCCCCCCCC
GLETAALAVAHLDNPLEWPHILRETYGEAFLLARTAARLLTYPQFLPLTGPIALRTPLMA
CHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
SAARLMGNLVTEEDKDIVARAWRAAGWGVTKIRGGSPLWD
HHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA