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The map label for this gene is qorA [H]

Identifier: 38232802

GI number: 38232802

Start: 149323

End: 150270

Strand: Reverse

Name: qorA [H]

Synonym: DIP0177

Alternate gene names: 38232802

Gene position: 150270-149323 (Counterclockwise)

Preceding gene: 38232803

Following gene: 38232800

Centisome position: 6.04

GC content: 60.76

Gene sequence:

>948_bases
ATGAGGGCAATTTACGTTCAAGACGACGCCACCTTGGCAGTCCACGATGCACCAACACCCACCCTGCAACCAGGCGAAGT
ACTCGTCCAAGTCAAAGCAGCCGGCGTCAACCGCGCAGACCTCCTGCAGGCAGCAGGCCACTACCCGCCTCCCCCTGGTG
AATCGGAGATCATTGGGCTCGAGTGTGCCGGTGTGATCGTAGACGCAGGCACTACCAGCCGCAACGTCGGTGACAAGGTC
GCTTGTCTGCTGGCGGGCGGCGGATACGCCGAGTATGTGGCGGTGCCAGAGGGCCAGCTCATGCCGATTCCTGAGGGCTA
CAGCTTCGCTGAGGCGGCGGCCGTGGTGGAGGTTGCGGCCACGGTGTGGTCGAATATCGGGATGCTCACCGGCTTGAAGC
CCGAGCACATGTTTTTGATTCATGGTGGCGCGGGCGGGATCGGCACCTTTGCCATCCAGTTGGCTAAGCATGTGGGTGCC
ACGGTGGCGGTGACGGCGGGTTCGAAGGAGAAGCTGGAAACGTGTCGTGAGCTGGGCGCCGATATTCTGATTAATTATCG
GGAGGAGGATTTTGCAGAGGTCCTGAAGAATAAGTGCGATCGCATTTTGGACATTATGGGTGCGAAGTATCTGGACCAAA
ACGTGCGTGCATTGGCAATGGACGGCCACCAGGTGACCATCGGAATGCAAGGTGGTGTGAAGGGTGAGCTGAACATTGGG
CGGCTGCTGAGCAAGCGCGGCACGATCTCTGCGACGGCGTTGCGCGCCCGCGACCGCGAGGACAAGGCACGCATTGTGGC
GTCGACAGTCGAGAACGTGTGGCCACTGCTTGCCGACGGCACCATCCGGCACCACATCCACGCCACGCTCCCCCTAGAGC
AGGCCCAGCGGGCCCATGAGATGCTCAAAAATGGGGAGGTAACCGGAAAGCTCGTCCTCGAGGTTTAG

Upstream 100 bases:

>100_bases
TCTGCCACATCTCCAGTTGTGAGAACCCAAAAAACAAAGTTTCGGATCCAACGCGAAAAACTATACCCGAAGTTGCCGAA
ATTCTTTAAAGTGGGGGCGT

Downstream 100 bases:

>100_bases
GCGAAGCTCGCGACCACTCGCATCAGCTGGTCAACGTCGTGAGTGGTGTTAAACGGCGCCAAAGCCAAACTGATGGTGCC
GTGGGTGTCCTCGGCACCCA

Product: putative quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MRAIYVQDDATLAVHDAPTPTLQPGEVLVQVKAAGVNRADLLQAAGHYPPPPGESEIIGLECAGVIVDAGTTSRNVGDKV
ACLLAGGGYAEYVAVPEGQLMPIPEGYSFAEAAAVVEVAATVWSNIGMLTGLKPEHMFLIHGGAGGIGTFAIQLAKHVGA
TVAVTAGSKEKLETCRELGADILINYREEDFAEVLKNKCDRILDIMGAKYLDQNVRALAMDGHQVTIGMQGGVKGELNIG
RLLSKRGTISATALRARDREDKARIVASTVENVWPLLADGTIRHHIHATLPLEQAQRAHEMLKNGEVTGKLVLEV

Sequences:

>Translated_315_residues
MRAIYVQDDATLAVHDAPTPTLQPGEVLVQVKAAGVNRADLLQAAGHYPPPPGESEIIGLECAGVIVDAGTTSRNVGDKV
ACLLAGGGYAEYVAVPEGQLMPIPEGYSFAEAAAVVEVAATVWSNIGMLTGLKPEHMFLIHGGAGGIGTFAIQLAKHVGA
TVAVTAGSKEKLETCRELGADILINYREEDFAEVLKNKCDRILDIMGAKYLDQNVRALAMDGHQVTIGMQGGVKGELNIG
RLLSKRGTISATALRARDREDKARIVASTVENVWPLLADGTIRHHIHATLPLEQAQRAHEMLKNGEVTGKLVLEV
>Mature_315_residues
MRAIYVQDDATLAVHDAPTPTLQPGEVLVQVKAAGVNRADLLQAAGHYPPPPGESEIIGLECAGVIVDAGTTSRNVGDKV
ACLLAGGGYAEYVAVPEGQLMPIPEGYSFAEAAAVVEVAATVWSNIGMLTGLKPEHMFLIHGGAGGIGTFAIQLAKHVGA
TVAVTAGSKEKLETCRELGADILINYREEDFAEVLKNKCDRILDIMGAKYLDQNVRALAMDGHQVTIGMQGGVKGELNIG
RLLSKRGTISATALRARDREDKARIVASTVENVWPLLADGTIRHHIHATLPLEQAQRAHEMLKNGEVTGKLVLEV

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=319, Percent_Identity=39.4984326018809, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI22538444, Length=319, Percent_Identity=39.4984326018809, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI18379349, Length=308, Percent_Identity=27.5974025974026, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI28557745, Length=317, Percent_Identity=29.6529968454259, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI194239674, Length=307, Percent_Identity=26.3843648208469, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI13236495, Length=307, Percent_Identity=26.3843648208469, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI24308257, Length=319, Percent_Identity=23.8244514106583, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI194239676, Length=302, Percent_Identity=25.1655629139073, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI47519420, Length=328, Percent_Identity=27.7439024390244, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI41872631, Length=320, Percent_Identity=27.1875, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1790485, Length=298, Percent_Identity=29.8657718120805, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787863, Length=229, Percent_Identity=30.1310043668122, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=307, Percent_Identity=28.3387622149837, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71987554, Length=202, Percent_Identity=29.2079207920792, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319520, Length=316, Percent_Identity=28.4810126582279, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6323961, Length=347, Percent_Identity=23.9193083573487, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=351, Percent_Identity=23.6467236467236, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=349, Percent_Identity=23.7822349570201, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=215, Percent_Identity=26.5116279069767, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319945, Length=370, Percent_Identity=24.5945945945946, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24581345, Length=181, Percent_Identity=28.1767955801105, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33391; Mature: 33391

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAIYVQDDATLAVHDAPTPTLQPGEVLVQVKAAGVNRADLLQAAGHYPPPPGESEIIGL
CEEEEEECCCEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCEEEE
ECAGVIVDAGTTSRNVGDKVACLLAGGGYAEYVAVPEGQLMPIPEGYSFAEAAAVVEVAA
EEEEEEEECCCCCCCCCCEEEEEEECCCCEEEEECCCCCEEECCCCCCHHHHHHHHHHHH
TVWSNIGMLTGLKPEHMFLIHGGAGGIGTFAIQLAKHVGATVAVTAGSKEKLETCRELGA
HHHHCCCHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCC
DILINYREEDFAEVLKNKCDRILDIMGAKYLDQNVRALAMDGHQVTIGMQGGVKGELNIG
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCCCCCCHH
RLLSKRGTISATALRARDREDKARIVASTVENVWPLLADGTIRHHIHATLPLEQAQRAHE
HHHHCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHH
MLKNGEVTGKLVLEV
HHHCCCCCEEEEEEC
>Mature Secondary Structure
MRAIYVQDDATLAVHDAPTPTLQPGEVLVQVKAAGVNRADLLQAAGHYPPPPGESEIIGL
CEEEEEECCCEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCEEEE
ECAGVIVDAGTTSRNVGDKVACLLAGGGYAEYVAVPEGQLMPIPEGYSFAEAAAVVEVAA
EEEEEEEECCCCCCCCCCEEEEEEECCCCEEEEECCCCCEEECCCCCCHHHHHHHHHHHH
TVWSNIGMLTGLKPEHMFLIHGGAGGIGTFAIQLAKHVGATVAVTAGSKEKLETCRELGA
HHHHCCCHHCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCC
DILINYREEDFAEVLKNKCDRILDIMGAKYLDQNVRALAMDGHQVTIGMQGGVKGELNIG
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEECCCCCCCCCHH
RLLSKRGTISATALRARDREDKARIVASTVENVWPLLADGTIRHHIHATLPLEQAQRAHE
HHHHCCCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHH
MLKNGEVTGKLVLEV
HHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]