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The map label for this gene is rfbE [H]

Identifier: 38232799

GI number: 38232799

Start: 146339

End: 147118

Strand: Reverse

Name: rfbE [H]

Synonym: DIP0174

Alternate gene names: 38232799

Gene position: 147118-146339 (Counterclockwise)

Preceding gene: 38232800

Following gene: 38232793

Centisome position: 5.91

GC content: 59.49

Gene sequence:

>780_bases
ATGGTATCTATCGACACCTATAACGCCTGCGTTGACTTCCCCATCTTCGACGCCAAATCGCGCTCCATGAAAAAAGCATT
CCTCGGAGCAGCGGGCGGCGCCATCGGACGCAACAAAGACAACACCGTTGTCGTCGAAGCGCTTCGCGACGTCAACCTGC
ACCTGCGCGAAGGCGACCGCATCGGACTCGTCGGCCACAACGGTGCCGGCAAATCCACACTCCTGCGACTCCTCTCCGGA
ATCTACGAACCCACCCGCGGCTCCGCACACGTCCGCGGCCGCGTCGCCCCCGTGTTCGACCTCGGCGTAGGCATGGACCC
CGAAATCTCTGGATACGAAAACATCGTCATCCGCGGGCTCTTCCTCGGCCAAACCCGCAAACAAATGAAACAAAAAATGG
ACGAGATCGCCGATTTTACCGAACTCGGCGACTACCTCTCCATGCCACTACGCACCTACTCCACCGGCATGCGCATCCGC
CTCGCTCTTGGAGTAGTCACCTCCATCGAACCTGAAATCCTGCTTCTCGACGAAGGCATCGGAGCCGTCGACGCCGCCTT
CATGGCAAAAGCACGCGAACGCCTCTCCGACCTAGTCAAACGCTCCGGCATCCTCGTGTTCGCCTCCCACTCCAACGACT
TCCTCGTCCAACTATGCGACTCCGCACTCTGGGTCGACCACGGCACCATCCGCCAAGCCGGACCAGTAGCCGACATCGTA
GAAGCCTACGAAGGAAAAGAAGCAGCCGACCACATCCGCAGACTGCAAGCCAGAATGTAG

Upstream 100 bases:

>100_bases
GGGCTGCTGCACCGTCATCGGGCTTTTCATCGCCATGCTTGCCATGCGCCAATGGCGATTCCGCGTCAGCTACTGGGTTT
AAGAAGGAGAAGAACTCACC

Downstream 100 bases:

>100_bases
TACTAGCCAACATCCGGTGGGCTGGAATCTCTTCGTGAGATGTCCCAGCCCACCGGACCGATTTTTTAGCGGGTCGAGGA
GAAAGCCTCCGCGATGGTAT

Product: ABC transporter ATP-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MVSIDTYNACVDFPIFDAKSRSMKKAFLGAAGGAIGRNKDNTVVVEALRDVNLHLREGDRIGLVGHNGAGKSTLLRLLSG
IYEPTRGSAHVRGRVAPVFDLGVGMDPEISGYENIVIRGLFLGQTRKQMKQKMDEIADFTELGDYLSMPLRTYSTGMRIR
LALGVVTSIEPEILLLDEGIGAVDAAFMAKARERLSDLVKRSGILVFASHSNDFLVQLCDSALWVDHGTIRQAGPVADIV
EAYEGKEAADHIRRLQARM

Sequences:

>Translated_259_residues
MVSIDTYNACVDFPIFDAKSRSMKKAFLGAAGGAIGRNKDNTVVVEALRDVNLHLREGDRIGLVGHNGAGKSTLLRLLSG
IYEPTRGSAHVRGRVAPVFDLGVGMDPEISGYENIVIRGLFLGQTRKQMKQKMDEIADFTELGDYLSMPLRTYSTGMRIR
LALGVVTSIEPEILLLDEGIGAVDAAFMAKARERLSDLVKRSGILVFASHSNDFLVQLCDSALWVDHGTIRQAGPVADIV
EAYEGKEAADHIRRLQARM
>Mature_259_residues
MVSIDTYNACVDFPIFDAKSRSMKKAFLGAAGGAIGRNKDNTVVVEALRDVNLHLREGDRIGLVGHNGAGKSTLLRLLSG
IYEPTRGSAHVRGRVAPVFDLGVGMDPEISGYENIVIRGLFLGQTRKQMKQKMDEIADFTELGDYLSMPLRTYSTGMRIR
LALGVVTSIEPEILLLDEGIGAVDAAFMAKARERLSDLVKRSGILVFASHSNDFLVQLCDSALWVDHGTIRQAGPVADIV
EAYEGKEAADHIRRLQARM

Specific function: May form an ATP-driven O-antigen export apparatus, in association with RfbD [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI116734710, Length=191, Percent_Identity=29.3193717277487, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI27477115, Length=210, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI153792144, Length=209, Percent_Identity=28.2296650717703, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI27436953, Length=249, Percent_Identity=26.9076305220884, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI31657092, Length=213, Percent_Identity=25.3521126760563, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27262624, Length=206, Percent_Identity=26.6990291262136, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI27262626, Length=206, Percent_Identity=26.6990291262136, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI45446740, Length=202, Percent_Identity=25.7425742574257, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI47078218, Length=202, Percent_Identity=25.7425742574257, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI6005701, Length=187, Percent_Identity=29.4117647058824, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI9665248, Length=228, Percent_Identity=26.7543859649123, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1790467, Length=197, Percent_Identity=30.9644670050761, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87081709, Length=215, Percent_Identity=26.046511627907, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI48995001, Length=228, Percent_Identity=27.1929824561404, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789032, Length=224, Percent_Identity=26.3392857142857, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788450, Length=243, Percent_Identity=25.1028806584362, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787547, Length=217, Percent_Identity=24.8847926267281, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788761, Length=205, Percent_Identity=26.8292682926829, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87081791, Length=218, Percent_Identity=25.6880733944954, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787758, Length=208, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082267, Length=209, Percent_Identity=25.3588516746411, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787712, Length=206, Percent_Identity=25.7281553398058, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081782, Length=215, Percent_Identity=27.4418604651163, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787759, Length=234, Percent_Identity=26.4957264957265, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI48994943, Length=206, Percent_Identity=22.8155339805825, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1789751, Length=208, Percent_Identity=28.3653846153846, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788225, Length=210, Percent_Identity=23.8095238095238, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787370, Length=209, Percent_Identity=25.3588516746411, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=216, Percent_Identity=29.6296296296296, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI115533608, Length=184, Percent_Identity=28.2608695652174, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221500365, Length=174, Percent_Identity=28.1609195402299, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007184, Length=174, Percent_Identity=28.1609195402299, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 28288; Mature: 28288

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIDTYNACVDFPIFDAKSRSMKKAFLGAAGGAIGRNKDNTVVVEALRDVNLHLREGDR
CCEECCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHCCCEEEECCCE
IGLVGHNGAGKSTLLRLLSGIYEPTRGSAHVRGRVAPVFDLGVGMDPEISGYENIVIRGL
EEEEECCCCCHHHHHHHHHHHCCCCCCCCEECCCCCEEEECCCCCCCCCCCCCCEEEEEE
FLGQTRKQMKQKMDEIADFTELGDYLSMPLRTYSTGMRIRLALGVVTSIEPEILLLDEGI
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEEEEHHHCCCCCEEEEECCC
GAVDAAFMAKARERLSDLVKRSGILVFASHSNDFLVQLCDSALWVDHGTIRQAGPVADIV
CHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHH
EAYEGKEAADHIRRLQARM
HHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVSIDTYNACVDFPIFDAKSRSMKKAFLGAAGGAIGRNKDNTVVVEALRDVNLHLREGDR
CCEECCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHCCCEEEECCCE
IGLVGHNGAGKSTLLRLLSGIYEPTRGSAHVRGRVAPVFDLGVGMDPEISGYENIVIRGL
EEEEECCCCCHHHHHHHHHHHCCCCCCCCEECCCCCEEEECCCCCCCCCCCCCCEEEEEE
FLGQTRKQMKQKMDEIADFTELGDYLSMPLRTYSTGMRIRLALGVVTSIEPEILLLDEGI
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEEEEHHHCCCCCEEEEECCC
GAVDAAFMAKARERLSDLVKRSGILVFASHSNDFLVQLCDSALWVDHGTIRQAGPVADIV
CHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHH
EAYEGKEAADHIRRLQARM
HHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7692217 [H]