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The map label for this gene is guaA [H]

Identifier: 38232762

GI number: 38232762

Start: 113937

End: 114524

Strand: Direct

Name: guaA [H]

Synonym: DIP0134

Alternate gene names: 38232762

Gene position: 113937-114524 (Clockwise)

Preceding gene: 38232761

Following gene: 38232763

Centisome position: 4.58

GC content: 58.16

Gene sequence:

>588_bases
ATGAACGGTATGGATCTTATTTCTTGTGATGATGGTCGGGTACGCCCTGCGTGGGCGGTGGGGGATGCGCTGTTGCGTCA
TTATTACGACTATGAGTGGGGCGCACCGGTTCATTCGGAGTCGGGGTTGTTTGAGCGATTAGCGCTAGAGGGGTTCCAGT
CGGGGTTGAGTTGGCGGACGGTGCTGCAGAAGCGCGCTGCTTTTCGGGAGGTTTTCTGGGGGTTTGATGCGGATCGGGTG
GCGTGTATGACGGAGGCGGATGTGCAGGCTTTGCTTGTCGACGCCCGCCTGATTCGCAATCGGCGCAAAATCATGGCGGT
GGTCAATAACGCTCGTGCTGTGATTGATCTGCGTGAGCATGGTGGCTTGGATGAGGTGTTGTGGTCGTTTGCACCGGCGC
AGCATACGCCTCCTCTTACGGTGGCGGATATCCCTTCGCAGACGGTGGAGTCTCGGGCGATGGCTAAAGAGTTGAAGCGT
TGTGGTTTCCAATTTGTCGGGCCTACCACGTGCTATGCCACGATGCAGGCGGTGGGGATGGTAGATGATCGCCCCCGTGG
CGCGTCGCCACTTCTCGTGGAAAGCTAG

Upstream 100 bases:

>100_bases
GTGTCTCAGGGGCGGATAAATCTGACATTTCGGCAGGTAAAGCTATAGCTTCCCCCTGTTTTACCCCCGCGTGTTGGAGG
GATGTTTTAGCCTCGCTGTT

Downstream 100 bases:

>100_bases
TGCCATGTCGAATCAACATGTGGTTAATGAGAAAAAGATTGCGGTTGTTACCGGTGCCTCCTCTGGCATTGGTGAGGCTG
CCGCGCGTGCTCTTGCGGCC

Product: putative DNA-repair protein

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MNGMDLISCDDGRVRPAWAVGDALLRHYYDYEWGAPVHSESGLFERLALEGFQSGLSWRTVLQKRAAFREVFWGFDADRV
ACMTEADVQALLVDARLIRNRRKIMAVVNNARAVIDLREHGGLDEVLWSFAPAQHTPPLTVADIPSQTVESRAMAKELKR
CGFQFVGPTTCYATMQAVGMVDDRPRGASPLLVES

Sequences:

>Translated_195_residues
MNGMDLISCDDGRVRPAWAVGDALLRHYYDYEWGAPVHSESGLFERLALEGFQSGLSWRTVLQKRAAFREVFWGFDADRV
ACMTEADVQALLVDARLIRNRRKIMAVVNNARAVIDLREHGGLDEVLWSFAPAQHTPPLTVADIPSQTVESRAMAKELKR
CGFQFVGPTTCYATMQAVGMVDDRPRGASPLLVES
>Mature_195_residues
MNGMDLISCDDGRVRPAWAVGDALLRHYYDYEWGAPVHSESGLFERLALEGFQSGLSWRTVLQKRAAFREVFWGFDADRV
ACMTEADVQALLVDARLIRNRRKIMAVVNNARAVIDLREHGGLDEVLWSFAPAQHTPPLTVADIPSQTVESRAMAKELKR
CGFQFVGPTTCYATMQAVGMVDDRPRGASPLLVES

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=177, Percent_Identity=44.6327683615819, Blast_Score=149, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 21742; Mature: 21742

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGMDLISCDDGRVRPAWAVGDALLRHYYDYEWGAPVHSESGLFERLALEGFQSGLSWRT
CCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHH
VLQKRAAFREVFWGFDADRVACMTEADVQALLVDARLIRNRRKIMAVVNNARAVIDLREH
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHC
GGLDEVLWSFAPAQHTPPLTVADIPSQTVESRAMAKELKRCGFQFVGPTTCYATMQAVGM
CCHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
VDDRPRGASPLLVES
CCCCCCCCCCCEECC
>Mature Secondary Structure
MNGMDLISCDDGRVRPAWAVGDALLRHYYDYEWGAPVHSESGLFERLALEGFQSGLSWRT
CCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHH
VLQKRAAFREVFWGFDADRVACMTEADVQALLVDARLIRNRRKIMAVVNNARAVIDLREH
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHC
GGLDEVLWSFAPAQHTPPLTVADIPSQTVESRAMAKELKRCGFQFVGPTTCYATMQAVGM
CCHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
VDDRPRGASPLLVES
CCCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]