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The map label for this gene is rhtC [H]

Identifier: 37681374

GI number: 37681374

Start: 3278816

End: 3279487

Strand: Direct

Name: rhtC [H]

Synonym: VV3190

Alternate gene names: 37681374

Gene position: 3278816-3279487 (Clockwise)

Preceding gene: 37681373

Following gene: 37681377

Centisome position: 97.74

GC content: 50.45

Gene sequence:

>672_bases
ATGAACGAACTGACGATTTTACTGACGCTGGCAAGCGTCCACTTTATTGCTTTGATGAGCCCCGGCCCCGACATGGCACT
GGTCGTGCAAAACGCAAGCCGCTATGGCCGCCAAACGGGCCTTTTTATTGCCCTCGGTTTGTCTGTTGGCATTTTGCTGC
ATTCTCTATTAAGCCTGACGGGCGTGAGTTACTTGGTCCACCAGCAACCGATGTTGTATGCCTTATTGCAACTGCTGGGT
GGCAGCTATTTGCTCTATTTGGGCATTGGCGCGTTACGTTCCGTATTACGTCATTGGCGTCAGCCATCGGTGAATCCCAC
CACCACTCAACGGCAGTGGACGCTGAACACGAAACGCCAAGCCTTTCTCAAAGGCTTTGCCACCAACATTCTCAATCCCA
AGGCGTTAGTGTTTTTTGTCAGTCTGCTATCGAGCTTAATCCCAGCAACCATGTCGCTCTCTGGCAAGGCCACAGCGGTG
ATGATTTTATTTGCGTTGTCATTTCTTTGGTTTGCCAGCTTAGCGTGGGCGCTCTCTGGCCGCCGAATGCAACAGCATTT
ACACAAAGCGAGTGTCTATATTGATGGCATTTGCGGCGTTTTATTCTGCTTAATTGGCGCGGGTATCCTCTACAACACGG
TGATTCATCAAGTCATCAGCCAAGTTGCATAG

Upstream 100 bases:

>100_bases
AATTGCACGTTAGTGTTGCCTGTGTCAGTTTTTTACAAGCGCAAAGCCGCGCAACCCGAGACAATCAACACTCGATTTTG
ATGATGCACGAGAAACACTC

Downstream 100 bases:

>100_bases
TCTTTTGCTCGTTGCCGTGTAAGAGATCTCTCACAAACGAGTAAGCCAATGTCGTTTTTTATGTAAGACACCGGAGAGAA
AACAACTCTAACATTATGAT

Product: putative threonine efflux protein

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MNELTILLTLASVHFIALMSPGPDMALVVQNASRYGRQTGLFIALGLSVGILLHSLLSLTGVSYLVHQQPMLYALLQLLG
GSYLLYLGIGALRSVLRHWRQPSVNPTTTQRQWTLNTKRQAFLKGFATNILNPKALVFFVSLLSSLIPATMSLSGKATAV
MILFALSFLWFASLAWALSGRRMQQHLHKASVYIDGICGVLFCLIGAGILYNTVIHQVISQVA

Sequences:

>Translated_223_residues
MNELTILLTLASVHFIALMSPGPDMALVVQNASRYGRQTGLFIALGLSVGILLHSLLSLTGVSYLVHQQPMLYALLQLLG
GSYLLYLGIGALRSVLRHWRQPSVNPTTTQRQWTLNTKRQAFLKGFATNILNPKALVFFVSLLSSLIPATMSLSGKATAV
MILFALSFLWFASLAWALSGRRMQQHLHKASVYIDGICGVLFCLIGAGILYNTVIHQVISQVA
>Mature_223_residues
MNELTILLTLASVHFIALMSPGPDMALVVQNASRYGRQTGLFIALGLSVGILLHSLLSLTGVSYLVHQQPMLYALLQLLG
GSYLLYLGIGALRSVLRHWRQPSVNPTTTQRQWTLNTKRQAFLKGFATNILNPKALVFFVSLLSSLIPATMSLSGKATAV
MILFALSFLWFASLAWALSGRRMQQHLHKASVYIDGICGVLFCLIGAGILYNTVIHQVISQVA

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=218, Percent_Identity=29.3577981651376, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786522, Length=209, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788099, Length=141, Percent_Identity=29.7872340425532, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 24382; Mature: 24382

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELTILLTLASVHFIALMSPGPDMALVVQNASRYGRQTGLFIALGLSVGILLHSLLSLT
CCCHHHHHHHHHHHHHHEECCCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GVSYLVHQQPMLYALLQLLGGSYLLYLGIGALRSVLRHWRQPSVNPTTTQRQWTLNTKRQ
HHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHH
AFLKGFATNILNPKALVFFVSLLSSLIPATMSLSGKATAVMILFALSFLWFASLAWALSG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RRMQQHLHKASVYIDGICGVLFCLIGAGILYNTVIHQVISQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNELTILLTLASVHFIALMSPGPDMALVVQNASRYGRQTGLFIALGLSVGILLHSLLSLT
CCCHHHHHHHHHHHHHHEECCCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GVSYLVHQQPMLYALLQLLGGSYLLYLGIGALRSVLRHWRQPSVNPTTTQRQWTLNTKRQ
HHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHH
AFLKGFATNILNPKALVFFVSLLSSLIPATMSLSGKATAVMILFALSFLWFASLAWALSG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RRMQQHLHKASVYIDGICGVLFCLIGAGILYNTVIHQVISQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]