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The map label for this gene is argE [H]

Identifier: 37681187

GI number: 37681187

Start: 3080022

End: 3081158

Strand: Direct

Name: argE [H]

Synonym: VV3003

Alternate gene names: 37681187

Gene position: 3080022-3081158 (Clockwise)

Preceding gene: 37681182

Following gene: 161486595

Centisome position: 91.82

GC content: 50.22

Gene sequence:

>1137_bases
ATGCAATTACCGAGTTTTCTTGATGTTTACCGTGGCTTAATTTCCACCTCATCCATCAGCTCTAGCGACCCAAGTTGGGA
TCAAGGCAACCAGGCGGTGATCGAAAAGCTCTCCGATTGGTTTTCGGCGTTGGGCTTTGATGTGGACGTCACCGAAGTCG
AACCGGGTAAATACAATTTATTGGCACAGAAAGGTCAGGGAGAGGGTGGCCTACTGTTGGCTGGACACAGTGATACGGTG
CCTTTTGATCAAGGCCGTTGGAGCTTTGACCCTCACCAACTCACCGAGAAAGACAACAAGTTCTATGGTTTAGGCACCGC
CGATATGAAAGGCTTCTTTGCCTTTATTTATGAAGCCGCCAAACGCATGGATTGGAAAGGACAAAATAAACCCCTTTATG
TGCTGGCGACGTGTGATGAAGAGACCACCATGCTCGGTGCGCGCCACTTTAGTGCGCATACCCCCTTTAAACCTGACTAC
TGCATCATTGGCGAACCGACGAGTTTAGTGCCTGTTCGTGGGCACAAAGGCCATGTCGCCAATGTCGTACGAGTCACAGG
GAAATCGGGCCACTCCTCTGATCCATCATTAGGGGTCAATGCCATCGAGATCATGCATGAAGTCCTGTTCGCGCTGATGC
AACTGCGTGATACGTTAATCAAACAGTATCATAACCCTGGGTTTGCGATCCCTTCTCCAACACTGAATCTTGGCCATATT
CATGGGGGCGATAGTGCCAACCGCATCTGCGGTTGCTGTGAGTTGCATTATGACGTAAGACCTCTTCCTGGCATTAGCCT
CGACGGTTTGGATAATCTGCTGCGTGGGGCACTAAAAGAGGTGGAAGCAAAATGGCCGGGACGGATTGAGATCGTGCCAC
TGCACGAGCCAATCCCTGGTTACGAGTGCCAACATGATCATCCATTTATTCATGGCATAGAAGATCTCTGTGGTACACCA
TCACAAACCGTGAACTACTGTACCGAAGCGCCATTTTTGCAGCAGCTCTGCCCCACATTGGTGCTGGGTCCGGGCTCTAT
CGACCAAGCTCACCAGCCAGATGAGTTCTTGGCGTTTGACTTTATCGACCCGACGATTGACGTGCTCAGTAAAGCAATGC
GCAAATACTGTTTTTAG

Upstream 100 bases:

>100_bases
TTAAAAATTGCTTTATATTGATTTTTTATTCATTAAATATGAGTTAATATGTGTTTTACCTTTTTGTTACCCAACTGTCA
ACAGGGGAAGTGAATAATCT

Downstream 100 bases:

>100_bases
CTGCATGTCGGCAGAGTGGCCTTGCGCCACTCTGCCTTATAAATTGTAATAAATTTTCAATATCGTTTATTTACAAAGCA
ATACTTTGCTTTAAGTCAGA

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MQLPSFLDVYRGLISTSSISSSDPSWDQGNQAVIEKLSDWFSALGFDVDVTEVEPGKYNLLAQKGQGEGGLLLAGHSDTV
PFDQGRWSFDPHQLTEKDNKFYGLGTADMKGFFAFIYEAAKRMDWKGQNKPLYVLATCDEETTMLGARHFSAHTPFKPDY
CIIGEPTSLVPVRGHKGHVANVVRVTGKSGHSSDPSLGVNAIEIMHEVLFALMQLRDTLIKQYHNPGFAIPSPTLNLGHI
HGGDSANRICGCCELHYDVRPLPGISLDGLDNLLRGALKEVEAKWPGRIEIVPLHEPIPGYECQHDHPFIHGIEDLCGTP
SQTVNYCTEAPFLQQLCPTLVLGPGSIDQAHQPDEFLAFDFIDPTIDVLSKAMRKYCF

Sequences:

>Translated_378_residues
MQLPSFLDVYRGLISTSSISSSDPSWDQGNQAVIEKLSDWFSALGFDVDVTEVEPGKYNLLAQKGQGEGGLLLAGHSDTV
PFDQGRWSFDPHQLTEKDNKFYGLGTADMKGFFAFIYEAAKRMDWKGQNKPLYVLATCDEETTMLGARHFSAHTPFKPDY
CIIGEPTSLVPVRGHKGHVANVVRVTGKSGHSSDPSLGVNAIEIMHEVLFALMQLRDTLIKQYHNPGFAIPSPTLNLGHI
HGGDSANRICGCCELHYDVRPLPGISLDGLDNLLRGALKEVEAKWPGRIEIVPLHEPIPGYECQHDHPFIHGIEDLCGTP
SQTVNYCTEAPFLQQLCPTLVLGPGSIDQAHQPDEFLAFDFIDPTIDVLSKAMRKYCF
>Mature_378_residues
MQLPSFLDVYRGLISTSSISSSDPSWDQGNQAVIEKLSDWFSALGFDVDVTEVEPGKYNLLAQKGQGEGGLLLAGHSDTV
PFDQGRWSFDPHQLTEKDNKFYGLGTADMKGFFAFIYEAAKRMDWKGQNKPLYVLATCDEETTMLGARHFSAHTPFKPDY
CIIGEPTSLVPVRGHKGHVANVVRVTGKSGHSSDPSLGVNAIEIMHEVLFALMQLRDTLIKQYHNPGFAIPSPTLNLGHI
HGGDSANRICGCCELHYDVRPLPGISLDGLDNLLRGALKEVEAKWPGRIEIVPLHEPIPGYECQHDHPFIHGIEDLCGTP
SQTVNYCTEAPFLQQLCPTLVLGPGSIDQAHQPDEFLAFDFIDPTIDVLSKAMRKYCF

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=380, Percent_Identity=58.421052631579, Blast_Score=479, Evalue=1e-136,
Organism=Escherichia coli, GI1788816, Length=257, Percent_Identity=29.5719844357977, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789236, Length=358, Percent_Identity=24.3016759776536, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17551016, Length=302, Percent_Identity=27.1523178807947, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 41721; Mature: 41721

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPSFLDVYRGLISTSSISSSDPSWDQGNQAVIEKLSDWFSALGFDVDVTEVEPGKYNL
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEE
LAQKGQGEGGLLLAGHSDTVPFDQGRWSFDPHQLTEKDNKFYGLGTADMKGFFAFIYEAA
EEECCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHH
KRMDWKGQNKPLYVLATCDEETTMLGARHFSAHTPFKPDYCIIGEPTSLVPVRGHKGHVA
HHCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCEEEECCCCCEEEECCCCCCEE
NVVRVTGKSGHSSDPSLGVNAIEIMHEVLFALMQLRDTLIKQYHNPGFAIPSPTLNLGHI
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECEE
HGGDSANRICGCCELHYDVRPLPGISLDGLDNLLRGALKEVEAKWPGRIEIVPLHEPIPG
ECCCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
YECQHDHPFIHGIEDLCGTPSQTVNYCTEAPFLQQLCPTLVLGPGSIDQAHQPDEFLAFD
CCCCCCCCHHHCHHHHCCCCHHHHHHHCCCHHHHHHHHHEEECCCCCCCCCCCCCEEEEE
FIDPTIDVLSKAMRKYCF
CCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLPSFLDVYRGLISTSSISSSDPSWDQGNQAVIEKLSDWFSALGFDVDVTEVEPGKYNL
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEE
LAQKGQGEGGLLLAGHSDTVPFDQGRWSFDPHQLTEKDNKFYGLGTADMKGFFAFIYEAA
EEECCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHCCCCCEEECCCHHHHHHHHHHHHHH
KRMDWKGQNKPLYVLATCDEETTMLGARHFSAHTPFKPDYCIIGEPTSLVPVRGHKGHVA
HHCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCEEEECCCCCEEEECCCCCCEE
NVVRVTGKSGHSSDPSLGVNAIEIMHEVLFALMQLRDTLIKQYHNPGFAIPSPTLNLGHI
EEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECEE
HGGDSANRICGCCELHYDVRPLPGISLDGLDNLLRGALKEVEAKWPGRIEIVPLHEPIPG
ECCCCCCHHEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
YECQHDHPFIHGIEDLCGTPSQTVNYCTEAPFLQQLCPTLVLGPGSIDQAHQPDEFLAFD
CCCCCCCCHHHCHHHHCCCCHHHHHHHCCCHHHHHHHHHEEECCCCCCCCCCCCCEEEEE
FIDPTIDVLSKAMRKYCF
CCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA