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The map label for this gene is coaE

Identifier: 37680966

GI number: 37680966

Start: 2838032

End: 2838640

Strand: Direct

Name: coaE

Synonym: VV2782

Alternate gene names: 37680966

Gene position: 2838032-2838640 (Clockwise)

Preceding gene: 37680965

Following gene: 37680967

Centisome position: 84.6

GC content: 48.93

Gene sequence:

>609_bases
ATGGCTTTAGTGATTGGATTGACTGGTGGTATCGCCAGCGGAAAAACGACGGTGGCCAATCTTTTTCAACAACACTTTGC
CATCGATATCGTCGACGCAGACATTGTCGCTCGTCAGGTAGTTGCCCCCGGAAGTGCGGGACTGGCCGCGATTGTTGACC
ATTTCGGTGCTGATATTCTGACTCGTGAAGGCGAACTCGATCGTGGACAACTTCGTCAGCGTATCTTTGCCCATGCCGAA
GAAAAGCAATGGCTCAACGCGCTACTGCACCCTATGATCCGTCGTAAAATGATCGAGGATCTGGCGCAAGTCTCATCCCC
TTACGCTTTGCTCGTTGTACCGCTGTTGGTAGAAAACCAACTACAGACTCTGTGCGACCGCGTTTTGGTCGTGGATGTTG
AAGAAAAAACACAATTACAGCGAACCATGGATCGTGACGGTGTAGATGAACAACAAGTTCGTGCCATACTCAAGGCTCAG
GCAAGCAGACACGAACGTCTCGCCTTGGCAGACGATGTGATTAAAAATGAGTCAAAAGACCAAGATCTTTTGCAGCAAAT
CACAGATTTACACCAAAAGTACCTAGCCATGAGCAAGCAAAATCGGTGA

Upstream 100 bases:

>100_bases
TTTCCATTTGGGCCTTATCTGGCCATTGCTGGTTGGGTCGCCTTAATGTGGGGAGATAGCTTGATGTCTTGGTATCTCAA
CTATCTTATAGGGGCATAAT

Downstream 100 bases:

>100_bases
AAATAAGTCAGAGACGACGACAGGCCCGCTAGATGACCACGCATAACTTCGAACATCCACTCAATGAAAAGACTCGCATT
TATCTGAGAGTCGAATCACT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MALVIGLTGGIASGKTTVANLFQQHFAIDIVDADIVARQVVAPGSAGLAAIVDHFGADILTREGELDRGQLRQRIFAHAE
EKQWLNALLHPMIRRKMIEDLAQVSSPYALLVVPLLVENQLQTLCDRVLVVDVEEKTQLQRTMDRDGVDEQQVRAILKAQ
ASRHERLALADDVIKNESKDQDLLQQITDLHQKYLAMSKQNR

Sequences:

>Translated_202_residues
MALVIGLTGGIASGKTTVANLFQQHFAIDIVDADIVARQVVAPGSAGLAAIVDHFGADILTREGELDRGQLRQRIFAHAE
EKQWLNALLHPMIRRKMIEDLAQVSSPYALLVVPLLVENQLQTLCDRVLVVDVEEKTQLQRTMDRDGVDEQQVRAILKAQ
ASRHERLALADDVIKNESKDQDLLQQITDLHQKYLAMSKQNR
>Mature_201_residues
ALVIGLTGGIASGKTTVANLFQQHFAIDIVDADIVARQVVAPGSAGLAAIVDHFGADILTREGELDRGQLRQRIFAHAEE
KQWLNALLHPMIRRKMIEDLAQVSSPYALLVVPLLVENQLQTLCDRVLVVDVEEKTQLQRTMDRDGVDEQQVRAILKAQA
SRHERLALADDVIKNESKDQDLLQQITDLHQKYLAMSKQNR

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=193, Percent_Identity=33.6787564766839, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI191252795, Length=193, Percent_Identity=33.6787564766839, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI110227607, Length=162, Percent_Identity=28.3950617283951, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI110227605, Length=162, Percent_Identity=28.3950617283951, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI110227603, Length=162, Percent_Identity=28.3950617283951, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI110227601, Length=162, Percent_Identity=28.3950617283951, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI205277394, Length=162, Percent_Identity=28.3950617283951, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1786292, Length=200, Percent_Identity=53, Blast_Score=208, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17554944, Length=190, Percent_Identity=31.5789473684211, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320402, Length=198, Percent_Identity=37.3737373737374, Blast_Score=125, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24644728, Length=204, Percent_Identity=27.9411764705882, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24658602, Length=188, Percent_Identity=28.7234042553192, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22562; Mature: 22431

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVIGLTGGIASGKTTVANLFQQHFAIDIVDADIVARQVVAPGSAGLAAIVDHFGADIL
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHH
TREGELDRGQLRQRIFAHAEEKQWLNALLHPMIRRKMIEDLAQVSSPYALLVVPLLVENQ
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQTLCDRVLVVDVEEKTQLQRTMDRDGVDEQQVRAILKAQASRHERLALADDVIKNESKD
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QDLLQQITDLHQKYLAMSKQNR
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALVIGLTGGIASGKTTVANLFQQHFAIDIVDADIVARQVVAPGSAGLAAIVDHFGADIL
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHH
TREGELDRGQLRQRIFAHAEEKQWLNALLHPMIRRKMIEDLAQVSSPYALLVVPLLVENQ
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQTLCDRVLVVDVEEKTQLQRTMDRDGVDEQQVRAILKAQASRHERLALADDVIKNESKD
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
QDLLQQITDLHQKYLAMSKQNR
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA