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The map label for this gene is int [H]

Identifier: 37680125

GI number: 37680125

Start: 1929942

End: 1930904

Strand: Direct

Name: int [H]

Synonym: VV1941

Alternate gene names: 37680125

Gene position: 1929942-1930904 (Clockwise)

Preceding gene: 37680104

Following gene: 37680130

Centisome position: 57.53

GC content: 41.33

Gene sequence:

>963_bases
ATGAAAAATCAGTTTATTTTAAGTGTTCAAGATCATATGCGAACTCGACACTATGCCACAAAAACGATTCAGGCTTACAT
CAGTTGGATTAAACAGTACATCTATTTCCATAGGATGGCACATCCGTCTACATTGAATGAGAAACATGTTGAAGAATTTT
TAACCCACCTCGCTGTTGAACAAAAAGTTGCCGCAAAGACACAAGCACTTGCATTAAACTCCGTTCTATTTCTCTATCGG
GAATATTTCAGAACACCGCTTAATAATGAAATTAAGTTTCAGAAGTCTCTACTCGATAGAAAATTGCCAGTTGTGTTGAC
CAAGCCAGAGCTTCGTGCATTTATTCAACATATAGACCCAAGATATAAACTTCATATTATGCTTTTATATGGCTCTGGAT
TAAGAGTTATGGAGTGCGTTCGTCTTAGAATCCAGGATATTGATTACCATTATGGAGCACTAAGAGTTTGGCAAGGCAAG
GGAGGGAAAAACCGCACTGTTACACTCGCTAAGGAGTTATATCCCCTCTTGAAAGAGCAAGAGGCACTAGCACTACGTTA
TTATCAAAAAGACAGAATTACTGCGGGTTACGCCGGCGTTTGGTTATCGTCTTCTCTGCAAAGAAAATACCAAGGAGCCG
AAATGGATTTCAACTGGCACTATTTATTCCCATCCGATAGGTTATCAAGAGATCCAGAGTCCGATTTACTCAGAAGACAT
CACATCAACGAGCAAGCTCTTCAAAGGGCCGTAAAGAGAGCAGCAAAAGATGCTGGAATTACCAAGTCCATAAGTTGCCA
CACGCTGAGACATAGCTTTGCAACACACTTACTTGAGTCCGGCGCCGATATTCGAACCGTACAAGAACAGCTAGGCCATT
CTGACGTTAAAACCACCCAGATATACACTCATGTATTAGAAAGAGGTGCGGGCGGAGTCCTAAGCCCTCTATCTAAGCTT
TAG

Upstream 100 bases:

>100_bases
CTAATAGTCTCAATTAGGCATTTAGATGTAGCTTAATTTTACAACTAGCCTAACTTTAAAAGGCTGTATATATACACATA
TAAAAACACAAAGGTTAGGA

Downstream 100 bases:

>100_bases
TTTCAGAATACAAAAAAGGAGAGCCTAAGCTCTCCTTTCTCTTAACCTAAACTCTAATTAAAGAGCTGCTTTCGCTTTTT
CAACTAGAACTGCAAATGCA

Product: super-integron integrase IntIA

Products: NA

Alternate protein names: E2 protein [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MKNQFILSVQDHMRTRHYATKTIQAYISWIKQYIYFHRMAHPSTLNEKHVEEFLTHLAVEQKVAAKTQALALNSVLFLYR
EYFRTPLNNEIKFQKSLLDRKLPVVLTKPELRAFIQHIDPRYKLHIMLLYGSGLRVMECVRLRIQDIDYHYGALRVWQGK
GGKNRTVTLAKELYPLLKEQEALALRYYQKDRITAGYAGVWLSSSLQRKYQGAEMDFNWHYLFPSDRLSRDPESDLLRRH
HINEQALQRAVKRAAKDAGITKSISCHTLRHSFATHLLESGADIRTVQEQLGHSDVKTTQIYTHVLERGAGGVLSPLSKL

Sequences:

>Translated_320_residues
MKNQFILSVQDHMRTRHYATKTIQAYISWIKQYIYFHRMAHPSTLNEKHVEEFLTHLAVEQKVAAKTQALALNSVLFLYR
EYFRTPLNNEIKFQKSLLDRKLPVVLTKPELRAFIQHIDPRYKLHIMLLYGSGLRVMECVRLRIQDIDYHYGALRVWQGK
GGKNRTVTLAKELYPLLKEQEALALRYYQKDRITAGYAGVWLSSSLQRKYQGAEMDFNWHYLFPSDRLSRDPESDLLRRH
HINEQALQRAVKRAAKDAGITKSISCHTLRHSFATHLLESGADIRTVQEQLGHSDVKTTQIYTHVLERGAGGVLSPLSKL
>Mature_320_residues
MKNQFILSVQDHMRTRHYATKTIQAYISWIKQYIYFHRMAHPSTLNEKHVEEFLTHLAVEQKVAAKTQALALNSVLFLYR
EYFRTPLNNEIKFQKSLLDRKLPVVLTKPELRAFIQHIDPRYKLHIMLLYGSGLRVMECVRLRIQDIDYHYGALRVWQGK
GGKNRTVTLAKELYPLLKEQEALALRYYQKDRITAGYAGVWLSSSLQRKYQGAEMDFNWHYLFPSDRLSRDPESDLLRRH
HINEQALQRAVKRAAKDAGITKSISCHTLRHSFATHLLESGADIRTVQEQLGHSDVKTTQIYTHVLERGAGGVLSPLSKL

Specific function: Putative integrase believed to be involved in the insertion of antibiotic resistance genes into plasmids and transposons [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=308, Percent_Identity=31.1688311688312, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1790244, Length=192, Percent_Identity=32.2916666666667, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR011946
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 37256; Mature: 37256

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQFILSVQDHMRTRHYATKTIQAYISWIKQYIYFHRMAHPSTLNEKHVEEFLTHLAVE
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
QKVAAKTQALALNSVLFLYREYFRTPLNNEIKFQKSLLDRKLPVVLTKPELRAFIQHIDP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEECHHHHHHHHHCCC
RYKLHIMLLYGSGLRVMECVRLRIQDIDYHYGALRVWQGKGGKNRTVTLAKELYPLLKEQ
CEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHH
EALALRYYQKDRITAGYAGVWLSSSLQRKYQGAEMDFNWHYLFPSDRLSRDPESDLLRRH
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHCCCCCHHHHHHHH
HINEQALQRAVKRAAKDAGITKSISCHTLRHSFATHLLESGADIRTVQEQLGHSDVKTTQ
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHH
IYTHVLERGAGGVLSPLSKL
HHHHHHHCCCCCCHHHHHCC
>Mature Secondary Structure
MKNQFILSVQDHMRTRHYATKTIQAYISWIKQYIYFHRMAHPSTLNEKHVEEFLTHLAVE
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
QKVAAKTQALALNSVLFLYREYFRTPLNNEIKFQKSLLDRKLPVVLTKPELRAFIQHIDP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEECHHHHHHHHHCCC
RYKLHIMLLYGSGLRVMECVRLRIQDIDYHYGALRVWQGKGGKNRTVTLAKELYPLLKEQ
CEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHHH
EALALRYYQKDRITAGYAGVWLSSSLQRKYQGAEMDFNWHYLFPSDRLSRDPESDLLRRH
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHCCCCCHHHHHHHH
HINEQALQRAVKRAAKDAGITKSISCHTLRHSFATHLLESGADIRTVQEQLGHSDVKTTQ
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHH
IYTHVLERGAGGVLSPLSKL
HHHHHHHCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2821509; 2823258; 3054482; 8195081; 2188588 [H]