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The map label for this gene is insF1 [H]

Identifier: 37680024

GI number: 37680024

Start: 1859342

End: 1860193

Strand: Direct

Name: insF1 [H]

Synonym: VV1840

Alternate gene names: 37680024

Gene position: 1859342-1860193 (Clockwise)

Preceding gene: 37680023

Following gene: 37680027

Centisome position: 55.43

GC content: 47.89

Gene sequence:

>852_bases
GTGAAGTACGAGTTCATTGAAAGCTATACCGGCGAGTACTCGATTAGCTTAATGTGTCGTACGCTAGAGGTGAGTCGAGG
TGGTTACTACAAGTGGTGTCATCACACGCAGAGTGAGCGTTCAAAGCGGCGAGAGCGCTTTGAACAGCTCGTCATGTGTA
CCTTTGCCCAATATCGGGCACGTTACGGTTCAGTGCGAATAGCCGAAGAGCTCAACGAAGCAGGCCATGCCTGCTGTGTG
AATTATGTGGCAGATATCATGAAGGAAAAAGGTATCAGGGCACGTAATGGTAAAGGGTTTAAATACAGCAAGGATGTGGC
TGCTATGACGAATGTTGCTGACAATTTACTGCGAAGAGACTTTGAGTCTGAGATGCCAAATCAGAAGTGGGTCACGGACA
TCACGTATATCTGGGTGAAGAGCCGTTGGCTCTTCTTGGCGACAGTGATGGACTTGCATTCAAGACGTATTGTGGGTTGG
TCGCTAGGGACAACAATGACCGTCGAGCTCATCACGAAAGCTCTAAAAATGGCGTTTGAGTCACGTAAGCCACCTAAGGG
CGTCATTATCCATTCGGACCGTGGTGTACAATACAGAGCATATAAATATCAAGACTTCATGCGTAAGCATGGAGGTGTAC
CGAGCATGAGTCGACAGGGTAACTGTTGGGATAATGCAGTGATGGAGTCGTTCTACAGTCGACTGAAAGTCGAGCTGATA
TACGCAGAAGACTACCAAACTGTCGAAGAAGCCCGAATGGGCATCTTCGAATACATCGAGGTATTTTACAATCGCAGAAG
AAGACACTCAGCGTTGGGGCATGTCAGCCCGGTTGAGTACGAAAGTATGTAG

Upstream 100 bases:

>100_bases
AGTCCGAAGAGCTTCGAGCGCTAAGGCACGAGAACAAGCGACTCAAAGAGGAAATGGAATTCCTAAAAAAGGTCTCGGCG
TACTTCGCGAAGCAGCAAGA

Downstream 100 bases:

>100_bases
TTATGTACTGTCTACTTTTGGTGGGGTACACCATTATCTTTAAAGGAGACTTCTAGCTCACAATTTATGCTGTATTCGGC
CTCACTATGACTATAAACGA

Product: transposase and inactivated derivative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKYEFIESYTGEYSISLMCRTLEVSRGGYYKWCHHTQSERSKRRERFEQLVMCTFAQYRARYGSVRIAEELNEAGHACCV
NYVADIMKEKGIRARNGKGFKYSKDVAAMTNVADNLLRRDFESEMPNQKWVTDITYIWVKSRWLFLATVMDLHSRRIVGW
SLGTTMTVELITKALKMAFESRKPPKGVIIHSDRGVQYRAYKYQDFMRKHGGVPSMSRQGNCWDNAVMESFYSRLKVELI
YAEDYQTVEEARMGIFEYIEVFYNRRRRHSALGHVSPVEYESM

Sequences:

>Translated_283_residues
MKYEFIESYTGEYSISLMCRTLEVSRGGYYKWCHHTQSERSKRRERFEQLVMCTFAQYRARYGSVRIAEELNEAGHACCV
NYVADIMKEKGIRARNGKGFKYSKDVAAMTNVADNLLRRDFESEMPNQKWVTDITYIWVKSRWLFLATVMDLHSRRIVGW
SLGTTMTVELITKALKMAFESRKPPKGVIIHSDRGVQYRAYKYQDFMRKHGGVPSMSRQGNCWDNAVMESFYSRLKVELI
YAEDYQTVEEARMGIFEYIEVFYNRRRRHSALGHVSPVEYESM
>Mature_283_residues
MKYEFIESYTGEYSISLMCRTLEVSRGGYYKWCHHTQSERSKRRERFEQLVMCTFAQYRARYGSVRIAEELNEAGHACCV
NYVADIMKEKGIRARNGKGFKYSKDVAAMTNVADNLLRRDFESEMPNQKWVTDITYIWVKSRWLFLATVMDLHSRRIVGW
SLGTTMTVELITKALKMAFESRKPPKGVIIHSDRGVQYRAYKYQDFMRKHGGVPSMSRQGNCWDNAVMESFYSRLKVELI
YAEDYQTVEEARMGIFEYIEVFYNRRRRHSALGHVSPVEYESM

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=268, Percent_Identity=31.3432835820896, Blast_Score=133, Evalue=2e-31,
Organism=Escherichia coli, GI1788405, Length=284, Percent_Identity=42.6056338028169, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1787263, Length=284, Percent_Identity=42.6056338028169, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1786753, Length=284, Percent_Identity=42.6056338028169, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1786570, Length=284, Percent_Identity=42.6056338028169, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1786490, Length=284, Percent_Identity=42.6056338028169, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1789981, Length=270, Percent_Identity=31.8518518518519, Blast_Score=156, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33347; Mature: 33347

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYEFIESYTGEYSISLMCRTLEVSRGGYYKWCHHTQSERSKRRERFEQLVMCTFAQYRA
CCCHHHHHCCCCEEEEEEEEEHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RYGSVRIAEELNEAGHACCVNYVADIMKEKGIRARNGKGFKYSKDVAAMTNVADNLLRRD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FESEMPNQKWVTDITYIWVKSRWLFLATVMDLHSRRIVGWSLGTTMTVELITKALKMAFE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHH
SRKPPKGVIIHSDRGVQYRAYKYQDFMRKHGGVPSMSRQGNCWDNAVMESFYSRLKVELI
CCCCCCCEEEECCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEE
YAEDYQTVEEARMGIFEYIEVFYNRRRRHSALGHVSPVEYESM
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKYEFIESYTGEYSISLMCRTLEVSRGGYYKWCHHTQSERSKRRERFEQLVMCTFAQYRA
CCCHHHHHCCCCEEEEEEEEEHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RYGSVRIAEELNEAGHACCVNYVADIMKEKGIRARNGKGFKYSKDVAAMTNVADNLLRRD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
FESEMPNQKWVTDITYIWVKSRWLFLATVMDLHSRRIVGWSLGTTMTVELITKALKMAFE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHH
SRKPPKGVIIHSDRGVQYRAYKYQDFMRKHGGVPSMSRQGNCWDNAVMESFYSRLKVELI
CCCCCCCEEEECCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHEEEEE
YAEDYQTVEEARMGIFEYIEVFYNRRRRHSALGHVSPVEYESM
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]