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The map label for this gene is hpcB [H]

Identifier: 37679772

GI number: 37679772

Start: 1629906

End: 1630937

Strand: Direct

Name: hpcB [H]

Synonym: VV1588

Alternate gene names: 37679772

Gene position: 1629906-1630937 (Clockwise)

Preceding gene: 37679771

Following gene: 37679773

Centisome position: 48.59

GC content: 46.9

Gene sequence:

>1032_bases
GTGCGCAGCAGTATTACTACCGACCACTCTGTTAGCGATGGTGACCGTGAGTGTTATGACCACCTTCGCGATGACACTAT
TTCAATAAGATCAGTATCTTGGAAGATCAAAACAATAACGAAGCATTGTGCGAGCAACGTATTAAACAATGCACTAGGTA
AAAGGAAATTAAGAATGGGTAAACTCTGTATCGCGGCTAAAATTACGCACGTCCCGACCATGATCATGTCAGAGCAACCA
GGCCGTTTATTCGGTTGCCGCCAAGCCGCTATTGATGGTCACAAAGAAATTGCCAAAATGGCAAAAGAGATGGACGTAGA
CACTATCATCGTGTTGGACACACACTGGTTGGTGAATGCGGGTTATCACATCAACTCAAATGACTCGTTTTCGGGCAACT
ACACCAGTCACGAGTTTCCACACTTCATCCAGAACCTTGAATATCAATATCGTGGCAACCGTGCGCTCGGTGATTTGATT
GCGGATAAGGCGACGGAAAAGGGCGTGTTTACCCTTTCTCACCAAGTGGATTCACTTGATCTGGAATACGGCACGTTAGT
TCCAATGCGCTTTATGAACCAAGATAACCATTTTAATGTTGTGTCGGTTGCGGCTTGGTGTACGGTTCACAACATTGAAT
CGTCTCGTATCCTTGGTGAAGCGATTCGCGAAGCGGTAGAACAGAGCGACAGCCGAGTAATGCTGCTTGCCTCTGGTTCG
TTGTCACACCGTATTTGGGACAACGATGAATACGAAGCAAACAACGGTACGTTTACGATTTCAAAAGAGTTTAACCGCCA
AGTTGATTTGCGCGTACTCGAGCTGTGGCGCAATCGTGATTACACAACATTCCTAGAAATGCTCCCTGACTATGCAGCGC
TGTGTTCTGGTGAAGGTGGTATGCACGACACCGCAATGTTGTTCGGTGCATTAGGCTGGGATCAATACCAAGGCGAAAGC
ACGGTGATCACCGAGTACTTCCCAAGCTCAGGTACCGGTCAAGTTAACGTCGTGTTTGAGGTTACGGAGTAA

Upstream 100 bases:

>100_bases
AACTTGATCCAACCATGAGTGCAGTCGCGGTGATTTTGGCCAGTATGCCGATGTTTGGTGTGTATGCCGTCATCGGACAA
AGGTACAACCTGGGAGGTAT

Downstream 100 bases:

>100_bases
GACATGAACTTAAATTACCCAGAGCTGTTTCAGCAGCGCTGCTACATCGACGGTCAGTGGGTTGCTGAAAGTGGTCAAAC
TCAAGCCGTAACGAATCCTT

Product: hypothetical protein

Products: NA

Alternate protein names: Homoprotocatechuate 2,3-dioxygenase; HPC dioxygenase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MRSSITTDHSVSDGDRECYDHLRDDTISIRSVSWKIKTITKHCASNVLNNALGKRKLRMGKLCIAAKITHVPTMIMSEQP
GRLFGCRQAAIDGHKEIAKMAKEMDVDTIIVLDTHWLVNAGYHINSNDSFSGNYTSHEFPHFIQNLEYQYRGNRALGDLI
ADKATEKGVFTLSHQVDSLDLEYGTLVPMRFMNQDNHFNVVSVAAWCTVHNIESSRILGEAIREAVEQSDSRVMLLASGS
LSHRIWDNDEYEANNGTFTISKEFNRQVDLRVLELWRNRDYTTFLEMLPDYAALCSGEGGMHDTAMLFGALGWDQYQGES
TVITEYFPSSGTGQVNVVFEVTE

Sequences:

>Translated_343_residues
MRSSITTDHSVSDGDRECYDHLRDDTISIRSVSWKIKTITKHCASNVLNNALGKRKLRMGKLCIAAKITHVPTMIMSEQP
GRLFGCRQAAIDGHKEIAKMAKEMDVDTIIVLDTHWLVNAGYHINSNDSFSGNYTSHEFPHFIQNLEYQYRGNRALGDLI
ADKATEKGVFTLSHQVDSLDLEYGTLVPMRFMNQDNHFNVVSVAAWCTVHNIESSRILGEAIREAVEQSDSRVMLLASGS
LSHRIWDNDEYEANNGTFTISKEFNRQVDLRVLELWRNRDYTTFLEMLPDYAALCSGEGGMHDTAMLFGALGWDQYQGES
TVITEYFPSSGTGQVNVVFEVTE
>Mature_343_residues
MRSSITTDHSVSDGDRECYDHLRDDTISIRSVSWKIKTITKHCASNVLNNALGKRKLRMGKLCIAAKITHVPTMIMSEQP
GRLFGCRQAAIDGHKEIAKMAKEMDVDTIIVLDTHWLVNAGYHINSNDSFSGNYTSHEFPHFIQNLEYQYRGNRALGDLI
ADKATEKGVFTLSHQVDSLDLEYGTLVPMRFMNQDNHFNVVSVAAWCTVHNIESSRILGEAIREAVEQSDSRVMLLASGS
LSHRIWDNDEYEANNGTFTISKEFNRQVDLRVLELWRNRDYTTFLEMLPDYAALCSGEGGMHDTAMLFGALGWDQYQGES
TVITEYFPSSGTGQVNVVFEVTE

Specific function: Transforms homoprotocatechuic acid (HPC) into 5- carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) [H]

COG id: COG3384

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011984
- InterPro:   IPR004183 [H]

Pfam domain/function: PF02900 LigB [H]

EC number: =1.13.11.15 [H]

Molecular weight: Translated: 38705; Mature: 38705

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSSITTDHSVSDGDRECYDHLRDDTISIRSVSWKIKTITKHCASNVLNNALGKRKLRMG
CCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
KLCIAAKITHVPTMIMSEQPGRLFGCRQAAIDGHKEIAKMAKEMDVDTIIVLDTHWLVNA
HHHEEEHHHHCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCEEEEC
GYHINSNDSFSGNYTSHEFPHFIQNLEYQYRGNRALGDLIADKATEKGVFTLSHQVDSLD
CEEECCCCCCCCCCCCCCHHHHHHCCCEEECCCCHHHHHHHHHCCCCCEEEEECCCCCCC
LEYGTLVPMRFMNQDNHFNVVSVAAWCTVHNIESSRILGEAIREAVEQSDSRVMLLASGS
CCCCCCCCHHCCCCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCC
LSHRIWDNDEYEANNGTFTISKEFNRQVDLRVLELWRNRDYTTFLEMLPDYAALCSGEGG
CCCCCCCCCCEECCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
MHDTAMLFGALGWDQYQGESTVITEYFPSSGTGQVNVVFEVTE
CCHHHHHHHHCCCHHHCCCCEEEEEECCCCCCCEEEEEEEECC
>Mature Secondary Structure
MRSSITTDHSVSDGDRECYDHLRDDTISIRSVSWKIKTITKHCASNVLNNALGKRKLRMG
CCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
KLCIAAKITHVPTMIMSEQPGRLFGCRQAAIDGHKEIAKMAKEMDVDTIIVLDTHWLVNA
HHHEEEHHHHCCCEEECCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCEEEEC
GYHINSNDSFSGNYTSHEFPHFIQNLEYQYRGNRALGDLIADKATEKGVFTLSHQVDSLD
CEEECCCCCCCCCCCCCCHHHHHHCCCEEECCCCHHHHHHHHHCCCCCEEEEECCCCCCC
LEYGTLVPMRFMNQDNHFNVVSVAAWCTVHNIESSRILGEAIREAVEQSDSRVMLLASGS
CCCCCCCCHHCCCCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCC
LSHRIWDNDEYEANNGTFTISKEFNRQVDLRVLELWRNRDYTTFLEMLPDYAALCSGEGG
CCCCCCCCCCEECCCCEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
MHDTAMLFGALGWDQYQGESTVITEYFPSSGTGQVNVVFEVTE
CCHHHHHHHHCCCHHHCCCCEEEEEECCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2261999 [H]