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The map label for this gene is cobT

Identifier: 37679658

GI number: 37679658

Start: 1511285

End: 1512313

Strand: Direct

Name: cobT

Synonym: VV1474

Alternate gene names: 37679658

Gene position: 1511285-1512313 (Clockwise)

Preceding gene: 37679651

Following gene: 37679659

Centisome position: 45.05

GC content: 53.16

Gene sequence:

>1029_bases
ATGTTAGAGCAACAATTTGCCGCTGAGATCCAGCACATCATCGACAACAAAACCAAACCGCTAGGCGCACTGGGGCAACT
CGAGCAAGTCGCCTTACAATTGGCACTCATCCAAAGCCAAGGTAAAGAGCAAGCGGCGACGCATATTGAGCTCAAGCAGC
CGCAGATGCTGCTTTTTGCCGGTGACCACGGTGTCGCGGATGAAGGGGTGAGCATCGCACCGAGTGCGGTGACACAACAA
ATGGTATTGAATTTTCTCGCAGGTGGCGCGGCGATAAACTGCTTTTGCGCGCTTCATAGCATCGACCTGACGGTGGTTGA
TTGTGGCATTTTGTTGCCTGTCGACAGTGACGCCCGGAATCTCATCTTACGTCGTTTGGGCTCACGCACCGCCAACTTTG
CGATTGAGTCGGCCATGACGATTGAGCAAGTCGAACAAGCTTTGCGCAATGGTCAACAAATAGCGGCAGAGAAAATCGCT
CAAGGCGCAGATTTATTGATGTTTGGCGAGATGGGCATTGCCAACACCAGCTCTGCCGCGGCGCTGCTCAGTGCGTTATC
TGGCCACGAAGTGGATCACTGTGTCGGCAGAGGTACGGGCATTAATGAAGAGCAACTGTCGCACAAAATTAAAGTCGTGG
CGCAAGGCGTGGGGCGCTGTGAAGGTCTATCGGTTAATGCGATCCTCGCTGAAGTCGGTGGGTTTGAGATCGTGACCATG
GCTGGCGCGTTTATCGCTGCGGCTGAGCATAAAACCCCAGTGCTGGTGGACGGTTTTATTGTTTCGGTCGCGGCCTATAT
CGCGACGTTGCTGAAACCGGAGGTGAGAGACTACTTGTTGTTCGCTCATCGCTCCGAAGAACAAGGGCACCAAATTGTGT
TGTCACTCCTTGAAGCGAAGCCTTTGCTGGATTTGGGGCTGCGTCTTGGTGAAGGAACAGGAGCTGCACTGGCGTACCCA
CTATTAAAAGCGGCGGCGCAGTTTTACAACAATATGGCAAGCTTCGAAAGCGCAGGAGTAACGGTTTGA

Upstream 100 bases:

>100_bases
CCTCGATGAAGCGTATCTTGACTCTTTCTCCACGATCCCTTCGCCTGTACACTAGAGAACTTCTTGTTTTTACGCCATTT
CGACACCAACAGGGACAGTT

Downstream 100 bases:

>100_bases
TATGAAAACCTGGCAGTATCAGTACCAATTGTTTTGTTTGGCGGTGAGCTTTTTTAGCCGTTTGCCTGTGCCGAAATCAA
CACCGTATAGTGATGAAAGA

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MLEQQFAAEIQHIIDNKTKPLGALGQLEQVALQLALIQSQGKEQAATHIELKQPQMLLFAGDHGVADEGVSIAPSAVTQQ
MVLNFLAGGAAINCFCALHSIDLTVVDCGILLPVDSDARNLILRRLGSRTANFAIESAMTIEQVEQALRNGQQIAAEKIA
QGADLLMFGEMGIANTSSAAALLSALSGHEVDHCVGRGTGINEEQLSHKIKVVAQGVGRCEGLSVNAILAEVGGFEIVTM
AGAFIAAAEHKTPVLVDGFIVSVAAYIATLLKPEVRDYLLFAHRSEEQGHQIVLSLLEAKPLLDLGLRLGEGTGAALAYP
LLKAAAQFYNNMASFESAGVTV

Sequences:

>Translated_342_residues
MLEQQFAAEIQHIIDNKTKPLGALGQLEQVALQLALIQSQGKEQAATHIELKQPQMLLFAGDHGVADEGVSIAPSAVTQQ
MVLNFLAGGAAINCFCALHSIDLTVVDCGILLPVDSDARNLILRRLGSRTANFAIESAMTIEQVEQALRNGQQIAAEKIA
QGADLLMFGEMGIANTSSAAALLSALSGHEVDHCVGRGTGINEEQLSHKIKVVAQGVGRCEGLSVNAILAEVGGFEIVTM
AGAFIAAAEHKTPVLVDGFIVSVAAYIATLLKPEVRDYLLFAHRSEEQGHQIVLSLLEAKPLLDLGLRLGEGTGAALAYP
LLKAAAQFYNNMASFESAGVTV
>Mature_342_residues
MLEQQFAAEIQHIIDNKTKPLGALGQLEQVALQLALIQSQGKEQAATHIELKQPQMLLFAGDHGVADEGVSIAPSAVTQQ
MVLNFLAGGAAINCFCALHSIDLTVVDCGILLPVDSDARNLILRRLGSRTANFAIESAMTIEQVEQALRNGQQIAAEKIA
QGADLLMFGEMGIANTSSAAALLSALSGHEVDHCVGRGTGINEEQLSHKIKVVAQGVGRCEGLSVNAILAEVGGFEIVTM
AGAFIAAAEHKTPVLVDGFIVSVAAYIATLLKPEVRDYLLFAHRSEEQGHQIVLSLLEAKPLLDLGLRLGEGTGAALAYP
LLKAAAQFYNNMASFESAGVTV

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=337, Percent_Identity=35.0148367952522, Blast_Score=181, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36069; Mature: 36069

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQQFAAEIQHIIDNKTKPLGALGQLEQVALQLALIQSQGKEQAATHIELKQPQMLLFA
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCEEEEEE
GDHGVADEGVSIAPSAVTQQMVLNFLAGGAAINCFCALHSIDLTVVDCGILLPVDSDARN
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECEEEEECCCCHHH
LILRRLGSRTANFAIESAMTIEQVEQALRNGQQIAAEKIAQGADLLMFGEMGIANTSSAA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCHHHH
ALLSALSGHEVDHCVGRGTGINEEQLSHKIKVVAQGVGRCEGLSVNAILAEVGGFEIVTM
HHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEH
AGAFIAAAEHKTPVLVDGFIVSVAAYIATLLKPEVRDYLLFAHRSEEQGHQIVLSLLEAK
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHCC
PLLDLGLRLGEGTGAALAYPLLKAAAQFYNNMASFESAGVTV
CHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLEQQFAAEIQHIIDNKTKPLGALGQLEQVALQLALIQSQGKEQAATHIELKQPQMLLFA
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCEEEEEE
GDHGVADEGVSIAPSAVTQQMVLNFLAGGAAINCFCALHSIDLTVVDCGILLPVDSDARN
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEECEEEEECCCCHHH
LILRRLGSRTANFAIESAMTIEQVEQALRNGQQIAAEKIAQGADLLMFGEMGIANTSSAA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCHHHH
ALLSALSGHEVDHCVGRGTGINEEQLSHKIKVVAQGVGRCEGLSVNAILAEVGGFEIVTM
HHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEEEEH
AGAFIAAAEHKTPVLVDGFIVSVAAYIATLLKPEVRDYLLFAHRSEEQGHQIVLSLLEAK
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHCC
PLLDLGLRLGEGTGAALAYPLLKAAAQFYNNMASFESAGVTV
CHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA