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The map label for this gene is cfa [H]

Identifier: 37679521

GI number: 37679521

Start: 1364506

End: 1365762

Strand: Direct

Name: cfa [H]

Synonym: VV1337

Alternate gene names: 37679521

Gene position: 1364506-1365762 (Clockwise)

Preceding gene: 37679520

Following gene: 37679522

Centisome position: 40.68

GC content: 42.48

Gene sequence:

>1257_bases
ATGTTAAATACTTCTTCGATGGCATTGACCTCTCCATTATCTACAGCACAAAAGGCGGCTAGGACTCTGATATTTAAGTG
CTTACAGCGTATGGAAATCGGCACTTTGACGGTCATTGAAAGTTTTCAAAGTGACTCTCAAGAGCGTAGTGAACGCTTTG
TAGGGGCACACAATCACAAGCCGGGTGTGGCCATTAGCGCAACAATAGAAGTCAAACACCCGGCATTTTATTCGCGTTTA
ATGCGGGGGGGCAGTATTGCTGCTGGTGAAGCCTATATGGATGGTTGGTGGGACAGTCCAGATTTAACTTCGTTAATGAA
ATTAATGGCGCTCAATCTGAATGCATTAGATGGATTAGAAAATCAAAGTAGCTGGGTCACCAAACTGCTGTACAAACTCA
GTCATTGGAGCAATCGAAATACGCAGGAAAACTCGCGTAAAAATATTCATGCCCATTATGATCTTGGTAATGACCTCTAC
AGAGTATTCTTGGATGAGAGAATGTTATATTCGTCAGCTCTTTATCGCTCGGATAGTGAATCATTAGAGCAAGCACAAAT
AAATAAAATGGATCGCTTGTGTCAGCAATTGCAATTAAAACCCAGTGATGAGGTGATTGAAATCGGCACAGGTTGGGGGG
CAATGGCGATATACATGGCGGAAACCTATGGATGCCGGGTGACAACCACGACGATTTCAGATGAGCAATATGACTACGCA
AAACAACAGATTGCAGAAAGAGGTTTGACTGAGCGTATTCAGTTATTGAAGAAAGATTATCGAGATTTAACTGGGCAGTT
TGATAAATTGGTTTCTATCGAAATGATAGAGGCGGTAGGTAAGCAATATTTACCTTCTTACATCAAGGTGTGCCAGTCGT
TATTAAAACCTGGTGGTTTGATGGCAATACAAGCGATCACCATCGCCGACCAACGTTACGAATATTACAGTAACAACGTC
GATTTTATTCAAAAATACATTTTCCCAGGTGGATTTTTGCCGTCAGTGACTTCACTGGCGCAAGCCACGACCCAATACAG
TGATTTAGTGATTAGGGATTTGTTTGATATTGGGATGGATTACGCAAAAACATTACAAGAATGGCACCGACGTTTTAACC
ACGCTGAAGAGCAAGTCAAAAGACTAGGGTATGACGAGCGATTCATTCGTATGTGGCGTTACTACCTAAGTTATTGTGAG
GGGGGATTCTTAGCTCGTAGCATCAGTACCGTACACATGACGCTTCAAAGAGCCTAG

Upstream 100 bases:

>100_bases
GTGCACCATTTTATTCGCATCCCAAATACCGCTCTCCAGCCAACCGGACTGAGAATAACAACTAAACTGTTAAGAATAAT
AAATTTAGGGAGAATTCTGC

Downstream 100 bases:

>100_bases
TATCATGGCTCTTATTCTCGCCTCTGCTTGGTTCAATCTCGTTTGGTTTCTGGCGGTTATTGGCACTGAGCAGTGGCAAT
GGGTCACACTTTGCTTTGCC

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MLNTSSMALTSPLSTAQKAARTLIFKCLQRMEIGTLTVIESFQSDSQERSERFVGAHNHKPGVAISATIEVKHPAFYSRL
MRGGSIAAGEAYMDGWWDSPDLTSLMKLMALNLNALDGLENQSSWVTKLLYKLSHWSNRNTQENSRKNIHAHYDLGNDLY
RVFLDERMLYSSALYRSDSESLEQAQINKMDRLCQQLQLKPSDEVIEIGTGWGAMAIYMAETYGCRVTTTTISDEQYDYA
KQQIAERGLTERIQLLKKDYRDLTGQFDKLVSIEMIEAVGKQYLPSYIKVCQSLLKPGGLMAIQAITIADQRYEYYSNNV
DFIQKYIFPGGFLPSVTSLAQATTQYSDLVIRDLFDIGMDYAKTLQEWHRRFNHAEEQVKRLGYDERFIRMWRYYLSYCE
GGFLARSISTVHMTLQRA

Sequences:

>Translated_418_residues
MLNTSSMALTSPLSTAQKAARTLIFKCLQRMEIGTLTVIESFQSDSQERSERFVGAHNHKPGVAISATIEVKHPAFYSRL
MRGGSIAAGEAYMDGWWDSPDLTSLMKLMALNLNALDGLENQSSWVTKLLYKLSHWSNRNTQENSRKNIHAHYDLGNDLY
RVFLDERMLYSSALYRSDSESLEQAQINKMDRLCQQLQLKPSDEVIEIGTGWGAMAIYMAETYGCRVTTTTISDEQYDYA
KQQIAERGLTERIQLLKKDYRDLTGQFDKLVSIEMIEAVGKQYLPSYIKVCQSLLKPGGLMAIQAITIADQRYEYYSNNV
DFIQKYIFPGGFLPSVTSLAQATTQYSDLVIRDLFDIGMDYAKTLQEWHRRFNHAEEQVKRLGYDERFIRMWRYYLSYCE
GGFLARSISTVHMTLQRA
>Mature_418_residues
MLNTSSMALTSPLSTAQKAARTLIFKCLQRMEIGTLTVIESFQSDSQERSERFVGAHNHKPGVAISATIEVKHPAFYSRL
MRGGSIAAGEAYMDGWWDSPDLTSLMKLMALNLNALDGLENQSSWVTKLLYKLSHWSNRNTQENSRKNIHAHYDLGNDLY
RVFLDERMLYSSALYRSDSESLEQAQINKMDRLCQQLQLKPSDEVIEIGTGWGAMAIYMAETYGCRVTTTTISDEQYDYA
KQQIAERGLTERIQLLKKDYRDLTGQFDKLVSIEMIEAVGKQYLPSYIKVCQSLLKPGGLMAIQAITIADQRYEYYSNNV
DFIQKYIFPGGFLPSVTSLAQATTQYSDLVIRDLFDIGMDYAKTLQEWHRRFNHAEEQVKRLGYDERFIRMWRYYLSYCE
GGFLARSISTVHMTLQRA

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=366, Percent_Identity=39.8907103825137, Blast_Score=231, Evalue=9e-62,
Organism=Caenorhabditis elegans, GI133904226, Length=384, Percent_Identity=36.4583333333333, Blast_Score=254, Evalue=7e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 47958; Mature: 47958

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTSSMALTSPLSTAQKAARTLIFKCLQRMEIGTLTVIESFQSDSQERSERFVGAHNHK
CCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCCCC
PGVAISATIEVKHPAFYSRLMRGGSIAAGEAYMDGWWDSPDLTSLMKLMALNLNALDGLE
CCEEEEEEEEECCHHHHHHHHCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHCCHHHCCCC
NQSSWVTKLLYKLSHWSNRNTQENSRKNIHAHYDLGNDLYRVFLDERMLYSSALYRSDSE
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHH
SLEQAQINKMDRLCQQLQLKPSDEVIEIGTGWGAMAIYMAETYGCRVTTTTISDEQYDYA
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCHHHHHH
KQQIAERGLTERIQLLKKDYRDLTGQFDKLVSIEMIEAVGKQYLPSYIKVCQSLLKPGGL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
MAIQAITIADQRYEYYSNNVDFIQKYIFPGGFLPSVTSLAQATTQYSDLVIRDLFDIGMD
EEEHEEHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
YAKTLQEWHRRFNHAEEQVKRLGYDERFIRMWRYYLSYCEGGFLARSISTVHMTLQRA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNTSSMALTSPLSTAQKAARTLIFKCLQRMEIGTLTVIESFQSDSQERSERFVGAHNHK
CCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHCCCCCCC
PGVAISATIEVKHPAFYSRLMRGGSIAAGEAYMDGWWDSPDLTSLMKLMALNLNALDGLE
CCEEEEEEEEECCHHHHHHHHCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHCCHHHCCCC
NQSSWVTKLLYKLSHWSNRNTQENSRKNIHAHYDLGNDLYRVFLDERMLYSSALYRSDSE
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCHH
SLEQAQINKMDRLCQQLQLKPSDEVIEIGTGWGAMAIYMAETYGCRVTTTTISDEQYDYA
HHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCCEEEEEECCCHHHHHH
KQQIAERGLTERIQLLKKDYRDLTGQFDKLVSIEMIEAVGKQYLPSYIKVCQSLLKPGGL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
MAIQAITIADQRYEYYSNNVDFIQKYIFPGGFLPSVTSLAQATTQYSDLVIRDLFDIGMD
EEEHEEHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHH
YAKTLQEWHRRFNHAEEQVKRLGYDERFIRMWRYYLSYCEGGFLARSISTVHMTLQRA
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]