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The map label for this gene is htpX [H]

Identifier: 37679516

GI number: 37679516

Start: 1360143

End: 1361009

Strand: Direct

Name: htpX [H]

Synonym: VV1332

Alternate gene names: 37679516

Gene position: 1360143-1361009 (Clockwise)

Preceding gene: 37679514

Following gene: 37679517

Centisome position: 40.55

GC content: 49.02

Gene sequence:

>867_bases
ATGAAGCGAGTCATGTTGTTTTTAATTACCAACTTAGCTGTGGTTCTAGTCCTCAGCGTCGTGTTGAACATTGTTTATGC
TGTAACTGGAATGCAGCCAGGGAGCCTCTCAGGTTTATTGGTGATGGCTGCGGTATTTGGTTTTGGTGGTGCATTTATCT
CCTTGATGATGTCAAAGGGGATGGCACTACGCTCTGTCGGTGGAATGGTGATCGAGAGCCCTCGTAACGAGACAGAGCAC
TGGTTATTGGAAACGGTGAGCCGCCAAGCTCAACAAGCGGGCATTGGTATGCCAACCGTTGCCATTTATGATTCGCCGGA
CATCAACGCGTTTGCAACTGGGGCAAAACGTGACGATTCGCTGGTCGCGGTTTCTACGGGTCTGTTGCACAACATGACGC
GTGATGAAGCAGAAGCGGTGCTGGCGCATGAGGTGAGCCATATTGCCAATGGTGACATGGTGACCATGACGTTGATGCAG
GGTGTTGTGAACACCTTCGTTATCTTCTTGTCTCGCTTTATTGCCAACATGGTGGCTTCTAATAACAGCGATGAAGAAGG
TGAAGGTTCAAACATGATGGTGTATTTCGCGGTTTCTATCGCGCTTGAGCTGGTGTTTGGTTTCCTCGCGAGCTTCATCA
CCATGTGGTATAGCCGTCATCGTGAATTCCATGCCGATGCGGGAGCCGCCCGTCTAGTTGGTAAAGAGAAAATGATAGCG
GCTCTAGAGCGTCTAAAAATGAGCCAAGAATCAAAACTGGATGGCACCATGATGGCATTTGGTATTAACGGTAAGCAATC
TCTAACAGAACTGCTTATGAGCCACCCGCCACTCGATAAGCGTATCGCTGCCCTTCGCAATTTCTAA

Upstream 100 bases:

>100_bases
TCACTTAACCTTGTTTTTAAACAAATTAGACTATATCTATTAGCAAAAGAGGCCAGCTCAACTGGCCATCAATATAAATA
AGCTTCTTTGGAGAAAAGTA

Downstream 100 bases:

>100_bases
TGATGCGACAAGTGAATCGCGAATCGATGCAAAGGTGAGCCAACTCATCACCGAATTGGATTCGAAACAGAAAGCCTGGA
GAACTCTCTCTGGGCTTTTT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MKRVMLFLITNLAVVLVLSVVLNIVYAVTGMQPGSLSGLLVMAAVFGFGGAFISLMMSKGMALRSVGGMVIESPRNETEH
WLLETVSRQAQQAGIGMPTVAIYDSPDINAFATGAKRDDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQ
GVVNTFVIFLSRFIANMVASNNSDEEGEGSNMMVYFAVSIALELVFGFLASFITMWYSRHREFHADAGAARLVGKEKMIA
ALERLKMSQESKLDGTMMAFGINGKQSLTELLMSHPPLDKRIAALRNF

Sequences:

>Translated_288_residues
MKRVMLFLITNLAVVLVLSVVLNIVYAVTGMQPGSLSGLLVMAAVFGFGGAFISLMMSKGMALRSVGGMVIESPRNETEH
WLLETVSRQAQQAGIGMPTVAIYDSPDINAFATGAKRDDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQ
GVVNTFVIFLSRFIANMVASNNSDEEGEGSNMMVYFAVSIALELVFGFLASFITMWYSRHREFHADAGAARLVGKEKMIA
ALERLKMSQESKLDGTMMAFGINGKQSLTELLMSHPPLDKRIAALRNF
>Mature_288_residues
MKRVMLFLITNLAVVLVLSVVLNIVYAVTGMQPGSLSGLLVMAAVFGFGGAFISLMMSKGMALRSVGGMVIESPRNETEH
WLLETVSRQAQQAGIGMPTVAIYDSPDINAFATGAKRDDSLVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQ
GVVNTFVIFLSRFIANMVASNNSDEEGEGSNMMVYFAVSIALELVFGFLASFITMWYSRHREFHADAGAARLVGKEKMIA
ALERLKMSQESKLDGTMMAFGINGKQSLTELLMSHPPLDKRIAALRNF

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=292, Percent_Identity=67.1232876712329, Blast_Score=389, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 31277; Mature: 31277

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.6 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.6 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVMLFLITNLAVVLVLSVVLNIVYAVTGMQPGSLSGLLVMAAVFGFGGAFISLMMSKG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
MALRSVGGMVIESPRNETEHWLLETVSRQAQQAGIGMPTVAIYDSPDINAFATGAKRDDS
HHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCCCCC
LVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQGVVNTFVIFLSRFIANMVAS
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NNSDEEGEGSNMMVYFAVSIALELVFGFLASFITMWYSRHREFHADAGAARLVGKEKMIA
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALERLKMSQESKLDGTMMAFGINGKQSLTELLMSHPPLDKRIAALRNF
HHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKRVMLFLITNLAVVLVLSVVLNIVYAVTGMQPGSLSGLLVMAAVFGFGGAFISLMMSKG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
MALRSVGGMVIESPRNETEHWLLETVSRQAQQAGIGMPTVAIYDSPDINAFATGAKRDDS
HHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCCCCC
LVAVSTGLLHNMTRDEAEAVLAHEVSHIANGDMVTMTLMQGVVNTFVIFLSRFIANMVAS
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NNSDEEGEGSNMMVYFAVSIALELVFGFLASFITMWYSRHREFHADAGAARLVGKEKMIA
CCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALERLKMSQESKLDGTMMAFGINGKQSLTELLMSHPPLDKRIAALRNF
HHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA