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The map label for this gene is moaE [H]

Identifier: 37679386

GI number: 37679386

Start: 1217073

End: 1217528

Strand: Direct

Name: moaE [H]

Synonym: VV1202

Alternate gene names: 37679386

Gene position: 1217073-1217528 (Clockwise)

Preceding gene: 37679385

Following gene: 37679387

Centisome position: 36.28

GC content: 49.78

Gene sequence:

>456_bases
GTGGATAATCGTATCTCAGTTCAAGTCGAAGATTTCGACATCGCAGCAGAATATGCGTGGTTGTCACAGGGGAGCGCGGC
AGGCGCTATCGTGACTTTTGTTGGCAAGGTGAGAGACATGAACTTGGGCGATAATGTCACGGGCCTAAGTTTGGAGCATT
ATCCAGGTATGACGGAAAAAGCGCTGGGTGAGATTTGTGATCAAGCCGAGCAGAGATGGCCGTTGCTGAATGTCCGTGTT
ATCCATCGAGTTGGCGACCTCAATATCGGTGATCAAATCGTGTATGTTGGGGTGTCGAGTGCACATCGCGGTGCGGCGTT
TGAGGCTTGTGAGTTCATTATGGATTATCTCAAGACCAAAGCGCCTTTCTGGAAAAAAGAACGTACAACTGAAACGACTC
GATGGGTTGAGTCTAGAGAGTCTGATGCCCAAGCGGCTGAGCGTTGGCAATCATAG

Upstream 100 bases:

>100_bases
AAATTGCTTGCTGCAGTCAATCAGTCGATTGTTCCACTGGAAACAACACTGCAAGATGGTGACGAAGTGGCCTTTTTCCC
TCCCGTGACAGGGGGGTAGC

Downstream 100 bases:

>100_bases
CGGTTTCCGCTATACGCGAAATTTGTGATTCAAAGCGATGGTTCGACCCATCGCTTTTGTTATTTTGCTGTGACAAAGCA
GTTTGTTGTGACCGAACAAA

Product: molybdenum cofactor biosynthesis protein E

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MDNRISVQVEDFDIAAEYAWLSQGSAAGAIVTFVGKVRDMNLGDNVTGLSLEHYPGMTEKALGEICDQAEQRWPLLNVRV
IHRVGDLNIGDQIVYVGVSSAHRGAAFEACEFIMDYLKTKAPFWKKERTTETTRWVESRESDAQAAERWQS

Sequences:

>Translated_151_residues
MDNRISVQVEDFDIAAEYAWLSQGSAAGAIVTFVGKVRDMNLGDNVTGLSLEHYPGMTEKALGEICDQAEQRWPLLNVRV
IHRVGDLNIGDQIVYVGVSSAHRGAAFEACEFIMDYLKTKAPFWKKERTTETTRWVESRESDAQAAERWQS
>Mature_151_residues
MDNRISVQVEDFDIAAEYAWLSQGSAAGAIVTFVGKVRDMNLGDNVTGLSLEHYPGMTEKALGEICDQAEQRWPLLNVRV
IHRVGDLNIGDQIVYVGVSSAHRGAAFEACEFIMDYLKTKAPFWKKERTTETTRWVESRESDAQAAERWQS

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=124, Percent_Identity=37.0967741935484, Blast_Score=95, Evalue=3e-20,
Organism=Escherichia coli, GI1787003, Length=148, Percent_Identity=62.8378378378378, Blast_Score=201, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17509279, Length=128, Percent_Identity=34.375, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356259, Length=133, Percent_Identity=34.5864661654135, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16969; Mature: 16969

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNRISVQVEDFDIAAEYAWLSQGSAAGAIVTFVGKVRDMNLGDNVTGLSLEHYPGMTEK
CCCEEEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCHH
ALGEICDQAEQRWPLLNVRVIHRVGDLNIGDQIVYVGVSSAHRGAAFEACEFIMDYLKTK
HHHHHHHHHHHHCCCCHHHEEEHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHC
APFWKKERTTETTRWVESRESDAQAAERWQS
CCCCCCCCCHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MDNRISVQVEDFDIAAEYAWLSQGSAAGAIVTFVGKVRDMNLGDNVTGLSLEHYPGMTEK
CCCEEEEEEECCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCHH
ALGEICDQAEQRWPLLNVRVIHRVGDLNIGDQIVYVGVSSAHRGAAFEACEFIMDYLKTK
HHHHHHHHHHHHCCCCHHHEEEHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHC
APFWKKERTTETTRWVESRESDAQAAERWQS
CCCCCCCCCHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]