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The map label for this gene is msrB [H]

Identifier: 37679332

GI number: 37679332

Start: 1160136

End: 1160600

Strand: Direct

Name: msrB [H]

Synonym: VV1148

Alternate gene names: 37679332

Gene position: 1160136-1160600 (Clockwise)

Preceding gene: 37679328

Following gene: 37679334

Centisome position: 34.58

GC content: 42.58

Gene sequence:

>465_bases
TTGCACAAAAAGTCGTCAACATTAATAAGAAAAAGGGAAATTAGTGACGTGACAAAAGAAAGTAAAGTTGTGCTCAAGTC
AGACCAGCAATGGCGTGAGCAGTTGTCTGAACAGGAATATCATGTGTGTCGTGAGCAAGGAACCGAACCTCCTTTTAGTG
GCAAGCTACTGCACAATAAAGACAGTGGAGAATATGCATGCACTTGCTGTTATGCGCCGCTGTTTTCTTCTGTTAACAAA
TACGACTCAGGCTGTGGTTGGCCAAGTTTTGATGCGCCGATTAATGAGACGGCTGTCCTGTATTTAGATGATTTTAGTCA
CGGAATGAAGCGAGTAGAGATCCGCTGTGCACGATGCGATAGCCACTTAGGGCACGTTTTTCCTGATGGACCTAAAACAA
CCGGAGAACGTTTTTGTGTCAATTCAGTGTCGTTAATTTTCAACAAAATTGAAACTAATGAGTGA

Upstream 100 bases:

>100_bases
GGCGTAAAATAACTCAAGAGCAGGTGCTCTAAGCAATTTTAAAACATAGGACATGATGGTGAGAAAGTATGTGCTACAAC
CATGATGCTTCGCAAGTTTT

Downstream 100 bases:

>100_bases
TTTTTCACCGAACGCTGTTCCCCGCTTTCAGTCATATCGTGTCTTGCTATCATACTGAAAGAGTCAAAATGGCGTGAGTA
ACCAAGAGACAAAAACCTTC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MHKKSSTLIRKREISDVTKESKVVLKSDQQWREQLSEQEYHVCREQGTEPPFSGKLLHNKDSGEYACTCCYAPLFSSVNK
YDSGCGWPSFDAPINETAVLYLDDFSHGMKRVEIRCARCDSHLGHVFPDGPKTTGERFCVNSVSLIFNKIETNE

Sequences:

>Translated_154_residues
MHKKSSTLIRKREISDVTKESKVVLKSDQQWREQLSEQEYHVCREQGTEPPFSGKLLHNKDSGEYACTCCYAPLFSSVNK
YDSGCGWPSFDAPINETAVLYLDDFSHGMKRVEIRCARCDSHLGHVFPDGPKTTGERFCVNSVSLIFNKIETNE
>Mature_154_residues
MHKKSSTLIRKREISDVTKESKVVLKSDQQWREQLSEQEYHVCREQGTEPPFSGKLLHNKDSGEYACTCCYAPLFSSVNK
YDSGCGWPSFDAPINETAVLYLDDFSHGMKRVEIRCARCDSHLGHVFPDGPKTTGERFCVNSVSLIFNKIETNE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI37620216, Length=135, Percent_Identity=49.6296296296296, Blast_Score=148, Evalue=2e-36,
Organism=Homo sapiens, GI301336164, Length=135, Percent_Identity=49.6296296296296, Blast_Score=148, Evalue=2e-36,
Organism=Homo sapiens, GI301336162, Length=135, Percent_Identity=49.6296296296296, Blast_Score=148, Evalue=2e-36,
Organism=Homo sapiens, GI73089054, Length=135, Percent_Identity=49.6296296296296, Blast_Score=148, Evalue=2e-36,
Organism=Homo sapiens, GI117606353, Length=128, Percent_Identity=49.21875, Blast_Score=136, Evalue=6e-33,
Organism=Escherichia coli, GI1788077, Length=128, Percent_Identity=58.59375, Blast_Score=171, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17553450, Length=122, Percent_Identity=48.3606557377049, Blast_Score=128, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI115532676, Length=122, Percent_Identity=48.3606557377049, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319816, Length=131, Percent_Identity=42.7480916030534, Blast_Score=100, Evalue=9e-23,
Organism=Drosophila melanogaster, GI221378664, Length=134, Percent_Identity=44.0298507462687, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24645799, Length=129, Percent_Identity=44.1860465116279, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI45553335, Length=129, Percent_Identity=44.1860465116279, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21356369, Length=129, Percent_Identity=44.1860465116279, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI221378662, Length=141, Percent_Identity=41.8439716312057, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24645801, Length=142, Percent_Identity=42.2535211267606, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24645804, Length=142, Percent_Identity=42.2535211267606, Blast_Score=114, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 17527; Mature: 17527

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKKSSTLIRKREISDVTKESKVVLKSDQQWREQLSEQEYHVCREQGTEPPFSGKLLHNK
CCCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECC
DSGEYACTCCYAPLFSSVNKYDSGCGWPSFDAPINETAVLYLDDFSHGMKRVEIRCARCD
CCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
SHLGHVFPDGPKTTGERFCVNSVSLIFNKIETNE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHKKSSTLIRKREISDVTKESKVVLKSDQQWREQLSEQEYHVCREQGTEPPFSGKLLHNK
CCCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECC
DSGEYACTCCYAPLFSSVNKYDSGCGWPSFDAPINETAVLYLDDFSHGMKRVEIRCARCD
CCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
SHLGHVFPDGPKTTGERFCVNSVSLIFNKIETNE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA