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The map label for this gene is nifU [H]

Identifier: 37678940

GI number: 37678940

Start: 761924

End: 762307

Strand: Direct

Name: nifU [H]

Synonym: VV0756

Alternate gene names: 37678940

Gene position: 761924-762307 (Clockwise)

Preceding gene: 37678939

Following gene: 37678941

Centisome position: 22.71

GC content: 43.75

Gene sequence:

>384_bases
ATGGCATACAGCGAAAAAGTAATTGATCACTATGAGAACCCACGTAACGTTGGTTCGTTTGACAAAGAAGATCCATCGGT
AGGTAGCGGCATGGTTGGTGCTCCTGCATGTGGTGACGTAATGAAACTGCAAATCAAAGTAACACCTGAAGGCATTATTG
AAGACGCAAAGTTCAAGACCTACGGTTGTGGTAGTGCGATTGCATCAAGCTCATTGGTTACTGAATGGGTAAAAGGCAAG
AGCATCGAAGAAGCGGCTTCGATCAAAAACTCGGAAATTGCAGAAGAGCTAGAATTGCCTCCAGTGAAAGTGCACTGTTC
AATTCTTGCAGAAGATGCAATCAAAGCCGCAGTGGCTGACTACAAGAAAAAACACCAACTTTAA

Upstream 100 bases:

>100_bases
TGGGATATGTACAAGGAAGGAATTGATCTCAACACGGTTGAGTGGGCTCACCACTAAGATCAATTCATAGACAAGTTATA
GAGGATTCGAGGTAAATATC

Downstream 100 bases:

>100_bases
GGTTTTTTTTGAGGTTATAATGGGGGCCTTATGCTCCCATTCCATTGGTAAACTATTTAACTAAGGTGCAGTATGGCCGT
TACATTAACAGATTCCGCAG

Product: scaffold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MAYSEKVIDHYENPRNVGSFDKEDPSVGSGMVGAPACGDVMKLQIKVTPEGIIEDAKFKTYGCGSAIASSSLVTEWVKGK
SIEEAASIKNSEIAEELELPPVKVHCSILAEDAIKAAVADYKKKHQL

Sequences:

>Translated_127_residues
MAYSEKVIDHYENPRNVGSFDKEDPSVGSGMVGAPACGDVMKLQIKVTPEGIIEDAKFKTYGCGSAIASSSLVTEWVKGK
SIEEAASIKNSEIAEELELPPVKVHCSILAEDAIKAAVADYKKKHQL
>Mature_126_residues
AYSEKVIDHYENPRNVGSFDKEDPSVGSGMVGAPACGDVMKLQIKVTPEGIIEDAKFKTYGCGSAIASSSLVTEWVKGKS
IEEAASIKNSEIAEELELPPVKVHCSILAEDAIKAAVADYKKKHQL

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=124, Percent_Identity=73.3870967741936, Blast_Score=197, Evalue=2e-51,
Organism=Homo sapiens, GI24307953, Length=124, Percent_Identity=72.5806451612903, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI1788878, Length=126, Percent_Identity=85.7142857142857, Blast_Score=228, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI17543474, Length=123, Percent_Identity=73.9837398373984, Blast_Score=196, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6325122, Length=125, Percent_Identity=68.8, Blast_Score=185, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6324800, Length=125, Percent_Identity=69.6, Blast_Score=181, Evalue=3e-47,
Organism=Drosophila melanogaster, GI21355597, Length=124, Percent_Identity=75.8064516129032, Blast_Score=202, Evalue=4e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011339
- InterPro:   IPR002871 [H]

Pfam domain/function: PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 13640; Mature: 13508

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSEKVIDHYENPRNVGSFDKEDPSVGSGMVGAPACGDVMKLQIKVTPEGIIEDAKFKT
CCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHCCCCCCC
YGCGSAIASSSLVTEWVKGKSIEEAASIKNSEIAEELELPPVKVHCSILAEDAIKAAVAD
CCCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHH
YKKKHQL
HHHHCCC
>Mature Secondary Structure 
AYSEKVIDHYENPRNVGSFDKEDPSVGSGMVGAPACGDVMKLQIKVTPEGIIEDAKFKT
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHCCCCCCC
YGCGSAIASSSLVTEWVKGKSIEEAASIKNSEIAEELELPPVKVHCSILAEDAIKAAVAD
CCCCHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHH
YKKKHQL
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]