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The map label for this gene is agaR [H]

Identifier: 37678720

GI number: 37678720

Start: 525048

End: 525866

Strand: Direct

Name: agaR [H]

Synonym: VV0536

Alternate gene names: 37678720

Gene position: 525048-525866 (Clockwise)

Preceding gene: 37678715

Following gene: 37678721

Centisome position: 15.65

GC content: 37.0

Gene sequence:

>819_bases
ATGTGCGTCGAAAAAGCTAGAGGGGACGCAGTAATGAAAACCGCCATAGAACGAAGACTCGAAATCGCGAATATGGTTGG
TGTACGTGGAAAGATGCACGTTGATGAGCTTGCCGAGTATTTCAATGTTACGGGAGCAACAATTCGTGCAGACCTACGTT
TTCTAGATGAGAACGGGTATATCGTACGCTCGCATGGTTTTGCATTAGTGAATCGAGATGTGCTGTCAAAACTTGCCATG
TCAGCAACGTCGAAAAATCAGAGTGGAAGCACAGATTTTTATGAATATGTTGCCCATGCGTTTTACGGGGCATTAGAAGA
GAAAAGTACGATTTTTGTTGATAGTAGTCCATTGATCAGAAAATCGTTGAAGTATCTTAAAGATCTTAAAGGAGCGACTG
TCGTTACACGAGATCTTAATTTGATTCAAAAGGTTCCCCACATAACGGATTGCAAATTTTTCGTTACAGGTGGTCGTGTG
AATACAGAGTATATGAAAATGACTGGTTCACACATGATAAATAGTTTAAGACAGTATCGTTTTAATAATGCGCTTATTCA
TGTAGAGAGTTTTAACACTAAGTTAGGGGTGTTCTCTAAAAGTGAGTTTGATGCTGACATGATTAGATTACTTTGCGATT
TGTCTGAGAAAATCACTATTGTAGTAGAGTCATCAGCTTTTAGTAATAACGACTCATTTTGGACATGTGAGCCAAATAAA
ATAGATACTGTCATCACGGATTACAATTTGGATGACGAAACGAAAAAGTCATTGGAATTGAATAATGTAAAAATATTAAA
GTTAAATATTAATAAATAA

Upstream 100 bases:

>100_bases
AAATTGTGAGTTTAGTCATGCTTAGGATAAAAAGTAATTGCTCAATAAAAAATCTTGAAAGAGAATTACTGCAAATGAAA
ACAAATAAAAAACCTGATTT

Downstream 100 bases:

>100_bases
AGGAAATTTACATGGCTAATATCGTTTTAGCACGTATTGATGAACGTCTAATTCACGGTCAAATTCGTCTTCAGTGGGGC
AAGCATTCTGGTGCAAATAC

Product: transcriptional regulator of sugar metabolism

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MCVEKARGDAVMKTAIERRLEIANMVGVRGKMHVDELAEYFNVTGATIRADLRFLDENGYIVRSHGFALVNRDVLSKLAM
SATSKNQSGSTDFYEYVAHAFYGALEEKSTIFVDSSPLIRKSLKYLKDLKGATVVTRDLNLIQKVPHITDCKFFVTGGRV
NTEYMKMTGSHMINSLRQYRFNNALIHVESFNTKLGVFSKSEFDADMIRLLCDLSEKITIVVESSAFSNNDSFWTCEPNK
IDTVITDYNLDDETKKSLELNNVKILKLNINK

Sequences:

>Translated_272_residues
MCVEKARGDAVMKTAIERRLEIANMVGVRGKMHVDELAEYFNVTGATIRADLRFLDENGYIVRSHGFALVNRDVLSKLAM
SATSKNQSGSTDFYEYVAHAFYGALEEKSTIFVDSSPLIRKSLKYLKDLKGATVVTRDLNLIQKVPHITDCKFFVTGGRV
NTEYMKMTGSHMINSLRQYRFNNALIHVESFNTKLGVFSKSEFDADMIRLLCDLSEKITIVVESSAFSNNDSFWTCEPNK
IDTVITDYNLDDETKKSLELNNVKILKLNINK
>Mature_272_residues
MCVEKARGDAVMKTAIERRLEIANMVGVRGKMHVDELAEYFNVTGATIRADLRFLDENGYIVRSHGFALVNRDVLSKLAM
SATSKNQSGSTDFYEYVAHAFYGALEEKSTIFVDSSPLIRKSLKYLKDLKGATVVTRDLNLIQKVPHITDCKFFVTGGRV
NTEYMKMTGSHMINSLRQYRFNNALIHVESFNTKLGVFSKSEFDADMIRLLCDLSEKITIVVESSAFSNNDSFWTCEPNK
IDTVITDYNLDDETKKSLELNNVKILKLNINK

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=261, Percent_Identity=22.9885057471264, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1789059, Length=251, Percent_Identity=21.9123505976096, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788069, Length=255, Percent_Identity=23.921568627451, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI226510968, Length=257, Percent_Identity=23.3463035019455, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787540, Length=261, Percent_Identity=24.1379310344828, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789829, Length=259, Percent_Identity=22.7799227799228, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 30799; Mature: 30799

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCVEKARGDAVMKTAIERRLEIANMVGVRGKMHVDELAEYFNVTGATIRADLRFLDENGY
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCE
IVRSHGFALVNRDVLSKLAMSATSKNQSGSTDFYEYVAHAFYGALEEKSTIFVDSSPLIR
EEEECCEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHH
KSLKYLKDLKGATVVTRDLNLIQKVPHITDCKFFVTGGRVNTEYMKMTGSHMINSLRQYR
HHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FNNALIHVESFNTKLGVFSKSEFDADMIRLLCDLSEKITIVVESSAFSNNDSFWTCEPNK
CCCEEEEEEECCCEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCC
IDTVITDYNLDDETKKSLELNNVKILKLNINK
EEEEEEECCCCCHHHHCEEECCEEEEEEECCC
>Mature Secondary Structure
MCVEKARGDAVMKTAIERRLEIANMVGVRGKMHVDELAEYFNVTGATIRADLRFLDENGY
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEEEEECCCCE
IVRSHGFALVNRDVLSKLAMSATSKNQSGSTDFYEYVAHAFYGALEEKSTIFVDSSPLIR
EEEECCEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHH
KSLKYLKDLKGATVVTRDLNLIQKVPHITDCKFFVTGGRVNTEYMKMTGSHMINSLRQYR
HHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
FNNALIHVESFNTKLGVFSKSEFDADMIRLLCDLSEKITIVVESSAFSNNDSFWTCEPNK
CCCEEEEEEECCCEEEECCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEECCCC
IDTVITDYNLDDETKKSLELNNVKILKLNINK
EEEEEEECCCCCHHHHCEEECCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]