Click here to switch to the map view.

The map label for this gene is ydjJ [H]

Identifier: 37678541

GI number: 37678541

Start: 365485

End: 367626

Strand: Direct

Name: ydjJ [H]

Synonym: VV0357

Alternate gene names: 37678541

Gene position: 365485-367626 (Clockwise)

Preceding gene: 37678540

Following gene: 37678542

Centisome position: 10.9

GC content: 44.21

Gene sequence:

>2142_bases
ATGAAACAAATATTACAAGACATGGCAAAAGGTACCTCTAATTTAGTTGAGGCACCTGCACCCACAACGTCAAAAGGCAA
TTTATTAATAAATACCTCTATTTCACTAATTTCTGCTGGCACAGAACGCATGCTAGTAGACTTCGGTAAGGCAAGTCTAC
TGGATAAAGCGCGTCAACAGCCTGACAAAGTTAAAATGATACTGGAAAAAGTCCAAACAGATGGGTTGATGACCACGTTA
GAGGCGGTTCAATCTAAGTTGGCGCAACCATTACCCTTAGGCTACTGCAATGTTGGTGTTGTCAATGCTGTTGGTAGAGG
TGTTAACGGATTTAAAGAAGGTGATCGCGTTGTTTCAAACGGCCCTCATGCAGATGTGGTACGTGTACCAAAAAACTTAT
GTGCGCTTATTCCTGATAATGTATCAGATGAGGAAGCATCATTTACCGTTGTAGCAAGTATTGGATTGCAAGGAATCCGT
TTAGCAGTGCCTACACTGGGTGAAGCGTTTGTCGTAACGGGTGTTGGCTTAATTGGGTTGCTGACGGTTCAATTGCTTCG
CGCTCAAGGTTGTCGTGTACTGGCCATTGATTATGACGATGCAAAACTAGAACTAGCTAAACAATTTGGCGCCCAAGTTT
GCAATCCTGGTAAAGGTGAAGATCCTGTCGCTGCAGGTATGGCATTTAGCCGTGGCAATGGAGTTGATGGTGTAATCATT
ACAGCTTCAACCAAATCTAATGATCCCGTAACACAAGCCGCGCGAATGAGCCGTAAGCGTGGACGTATTATTCTTGTTGG
TGTGACTGGGTTAGAGCTTAATCGTGCGGACTTCTACGAGAAAGAATTGACATTCCAAGTTTCTTGTTCTTATGGCCCTG
GCCGCTACGACGCAGACTACGAAGATAAGGGCAATGACTACCCTTACGCGTTTGTGCGTTGGACCGAGCAGCGTAACTTT
GAAGCCATCTTGGATATGATGTCTTCGGGCCAAGTAGACGTTAAGCCACTTATTACTCACCGATTTAAGTTTGAAGATGC
AGCGCAAGCATATGATCTACTCACCTCAGATAAGTCTGCACTGGGTATTTTGCTCCAGTATCAGAGTGAGCCCAGTACTC
GTCACCAGAAATCTGTTACGCTCAACAGTAAGGCTACTTTTGAAGTATCGAAGCCTGTCGTTGGGTTTGTTGGTGCTGGA
AACTACGCGTCTCGCATGTTGATCCCTGCGTTTAAAGCGGGTGGTGCCCAATTACATACTATTGCGACTTCTGGCGGTAT
TAATGGCGTTACACACGGTGAAAAAGCTGGTTTTGCGAAAACCACAACGGATACAAGCGCAATGATTTCAGACCCTGAAA
TCAACACTGTAGCTATTGTAACCCGCCATAACAGCCATGCACGTTTTGTTTGTGAGGCACTGAATGCTGGCAAGAATGTA
TTCGTTGAGAAACCGTTAGCCGTCACATTAGAAGAACTCGCTGAAGTCGAAGCAACTTATTACTCTAAAGCATCTAATGC
TTCTGAACCCAAATTGATGGTTGGCTTTAACCGTCGTTTCTCTCCTCAAGTACAAAAAATGAAAGCACTGCTTTCGTCGG
TTAAAGAGCCAAAAAGCTTCATGATGACAATGAATGCGGGAGCTATTCCGGCGGATCATTGGACACAAGATAATGAAGTC
GGCGGTGGTCGTATTATTGGAGAGGCGTGCCATTTCATTGATCTAATGAGATACCTAGCTGATTCAGAGATCGTTTCTGT
ACAGTGTCGTCGTATGGGAGATGTTTCCGGTGTTGATATTACCGAGGACAAAGCAGCTATTATTTTAGGCTTTGTAGATG
GCTCTTTCGGTACAATTCATTACCTAGCCAATGGTGCGGCTAACTTCCCAAAAGAACGTGTAGAAGTTTTCGCAGCAGGG
AGAGTACTTCAATTAGATAACTTCCGTAAGCTAAAAGGTTTCGGTTGGCCTGGCTTTAGCAAAATGAATTTATGGAAACA
AGATAAAGGCCAAACCAATTGTGCGGCTGCTTTCCTTAGCGCTATTGAATCAGGTAAAGAGTCACCAATTCCAGCTCGAG
AGTTGTTTGAGGTAGCAAGAGTTACCATTGAAATAGCGGATCAATTGCGTAAACAACAATGA

Upstream 100 bases:

>100_bases
GCAGTGCTTATTAACTATCCATCACCAAGTGAAAAGAAAAAAGCTTTGGAGTTGTAAACACTATTTGGGTTACGAAACGT
ATTTGAGAGATTAATTACTG

Downstream 100 bases:

>100_bases
GTCTCAAATTAAAAGCGCAAACTGCAATCGACTTAGGACTTTTAAACCTAGCTCGAGTCGCTGGCTATCAACTTGGTGTT
CGAAGTGGACTCAACCCAGT

Product: putatve zinc-binding dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 713; Mature: 713

Protein sequence:

>713_residues
MKQILQDMAKGTSNLVEAPAPTTSKGNLLINTSISLISAGTERMLVDFGKASLLDKARQQPDKVKMILEKVQTDGLMTTL
EAVQSKLAQPLPLGYCNVGVVNAVGRGVNGFKEGDRVVSNGPHADVVRVPKNLCALIPDNVSDEEASFTVVASIGLQGIR
LAVPTLGEAFVVTGVGLIGLLTVQLLRAQGCRVLAIDYDDAKLELAKQFGAQVCNPGKGEDPVAAGMAFSRGNGVDGVII
TASTKSNDPVTQAARMSRKRGRIILVGVTGLELNRADFYEKELTFQVSCSYGPGRYDADYEDKGNDYPYAFVRWTEQRNF
EAILDMMSSGQVDVKPLITHRFKFEDAAQAYDLLTSDKSALGILLQYQSEPSTRHQKSVTLNSKATFEVSKPVVGFVGAG
NYASRMLIPAFKAGGAQLHTIATSGGINGVTHGEKAGFAKTTTDTSAMISDPEINTVAIVTRHNSHARFVCEALNAGKNV
FVEKPLAVTLEELAEVEATYYSKASNASEPKLMVGFNRRFSPQVQKMKALLSSVKEPKSFMMTMNAGAIPADHWTQDNEV
GGGRIIGEACHFIDLMRYLADSEIVSVQCRRMGDVSGVDITEDKAAIILGFVDGSFGTIHYLANGAANFPKERVEVFAAG
RVLQLDNFRKLKGFGWPGFSKMNLWKQDKGQTNCAAAFLSAIESGKESPIPARELFEVARVTIEIADQLRKQQ

Sequences:

>Translated_713_residues
MKQILQDMAKGTSNLVEAPAPTTSKGNLLINTSISLISAGTERMLVDFGKASLLDKARQQPDKVKMILEKVQTDGLMTTL
EAVQSKLAQPLPLGYCNVGVVNAVGRGVNGFKEGDRVVSNGPHADVVRVPKNLCALIPDNVSDEEASFTVVASIGLQGIR
LAVPTLGEAFVVTGVGLIGLLTVQLLRAQGCRVLAIDYDDAKLELAKQFGAQVCNPGKGEDPVAAGMAFSRGNGVDGVII
TASTKSNDPVTQAARMSRKRGRIILVGVTGLELNRADFYEKELTFQVSCSYGPGRYDADYEDKGNDYPYAFVRWTEQRNF
EAILDMMSSGQVDVKPLITHRFKFEDAAQAYDLLTSDKSALGILLQYQSEPSTRHQKSVTLNSKATFEVSKPVVGFVGAG
NYASRMLIPAFKAGGAQLHTIATSGGINGVTHGEKAGFAKTTTDTSAMISDPEINTVAIVTRHNSHARFVCEALNAGKNV
FVEKPLAVTLEELAEVEATYYSKASNASEPKLMVGFNRRFSPQVQKMKALLSSVKEPKSFMMTMNAGAIPADHWTQDNEV
GGGRIIGEACHFIDLMRYLADSEIVSVQCRRMGDVSGVDITEDKAAIILGFVDGSFGTIHYLANGAANFPKERVEVFAAG
RVLQLDNFRKLKGFGWPGFSKMNLWKQDKGQTNCAAAFLSAIESGKESPIPARELFEVARVTIEIADQLRKQQ
>Mature_713_residues
MKQILQDMAKGTSNLVEAPAPTTSKGNLLINTSISLISAGTERMLVDFGKASLLDKARQQPDKVKMILEKVQTDGLMTTL
EAVQSKLAQPLPLGYCNVGVVNAVGRGVNGFKEGDRVVSNGPHADVVRVPKNLCALIPDNVSDEEASFTVVASIGLQGIR
LAVPTLGEAFVVTGVGLIGLLTVQLLRAQGCRVLAIDYDDAKLELAKQFGAQVCNPGKGEDPVAAGMAFSRGNGVDGVII
TASTKSNDPVTQAARMSRKRGRIILVGVTGLELNRADFYEKELTFQVSCSYGPGRYDADYEDKGNDYPYAFVRWTEQRNF
EAILDMMSSGQVDVKPLITHRFKFEDAAQAYDLLTSDKSALGILLQYQSEPSTRHQKSVTLNSKATFEVSKPVVGFVGAG
NYASRMLIPAFKAGGAQLHTIATSGGINGVTHGEKAGFAKTTTDTSAMISDPEINTVAIVTRHNSHARFVCEALNAGKNV
FVEKPLAVTLEELAEVEATYYSKASNASEPKLMVGFNRRFSPQVQKMKALLSSVKEPKSFMMTMNAGAIPADHWTQDNEV
GGGRIIGEACHFIDLMRYLADSEIVSVQCRRMGDVSGVDITEDKAAIILGFVDGSFGTIHYLANGAANFPKERVEVFAAG
RVLQLDNFRKLKGFGWPGFSKMNLWKQDKGQTNCAAAFLSAIESGKESPIPARELFEVARVTIEIADQLRKQQ

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=323, Percent_Identity=25.3869969040248, Blast_Score=81, Evalue=3e-15,
Organism=Escherichia coli, GI1788073, Length=310, Percent_Identity=27.0967741935484, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1788075, Length=252, Percent_Identity=26.5873015873016, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319955, Length=305, Percent_Identity=28.5245901639344, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322619, Length=305, Percent_Identity=28.5245901639344, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323099, Length=299, Percent_Identity=26.0869565217391, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319520, Length=160, Percent_Identity=30.625, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 77012; Mature: 77012

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQILQDMAKGTSNLVEAPAPTTSKGNLLINTSISLISAGTERMLVDFGKASLLDKARQQ
CHHHHHHHHCCHHHHCCCCCCCCCCCCEEEECCEEEECCCCHHHHHHCCHHHHHHHHHCC
PDKVKMILEKVQTDGLMTTLEAVQSKLAQPLPLGYCNVGVVNAVGRGVNGFKEGDRVVSN
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCEECCC
GPHADVVRVPKNLCALIPDNVSDEEASFTVVASIGLQGIRLAVPTLGEAFVVTGVGLIGL
CCCCCHHHCCHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHH
LTVQLLRAQGCRVLAIDYDDAKLELAKQFGAQVCNPGKGEDPVAAGMAFSRGNGVDGVII
HHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHCEEEECCCCCCEEEE
TASTKSNDPVTQAARMSRKRGRIILVGVTGLELNRADFYEKELTFQVSCSYGPGRYDADY
EECCCCCCHHHHHHHHHHHCCCEEEEEECCCEECCCHHHCEEEEEEEEECCCCCCCCCCC
EDKGNDYPYAFVRWTEQRNFEAILDMMSSGQVDVKPLITHRFKFEDAAQAYDLLTSDKSA
CCCCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEHHHHHEECCCHHHHHHHHHCCCCCC
LGILLQYQSEPSTRHQKSVTLNSKATFEVSKPVVGFVGAGNYASRMLIPAFKAGGAQLHT
EEEEEEECCCCCCCCCCEEEECCCEEEEECCCEEEEEECCCHHHHEEEEHHCCCCCEEEE
IATSGGINGVTHGEKAGFAKTTTDTSAMISDPEINTVAIVTRHNSHARFVCEALNAGKNV
EEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCHHHHHHHHCCCCCE
FVEKPLAVTLEELAEVEATYYSKASNASEPKLMVGFNRRFSPQVQKMKALLSSVKEPKSF
EEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCE
MMTMNAGAIPADHWTQDNEVGGGRIIGEACHFIDLMRYLADSEIVSVQCRRMGDVSGVDI
EEEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCEE
TEDKAAIILGFVDGSFGTIHYLANGAANFPKERVEVFAAGRVLQLDNFRKLKGFGWPGFS
CCCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEECCCHHHCCCCCCCCC
KMNLWKQDKGQTNCAAAFLSAIESGKESPIPARELFEVARVTIEIADQLRKQQ
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQILQDMAKGTSNLVEAPAPTTSKGNLLINTSISLISAGTERMLVDFGKASLLDKARQQ
CHHHHHHHHCCHHHHCCCCCCCCCCCCEEEECCEEEECCCCHHHHHHCCHHHHHHHHHCC
PDKVKMILEKVQTDGLMTTLEAVQSKLAQPLPLGYCNVGVVNAVGRGVNGFKEGDRVVSN
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCCEECCC
GPHADVVRVPKNLCALIPDNVSDEEASFTVVASIGLQGIRLAVPTLGEAFVVTGVGLIGL
CCCCCHHHCCHHHHHCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHH
LTVQLLRAQGCRVLAIDYDDAKLELAKQFGAQVCNPGKGEDPVAAGMAFSRGNGVDGVII
HHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCHHHCEEEECCCCCCEEEE
TASTKSNDPVTQAARMSRKRGRIILVGVTGLELNRADFYEKELTFQVSCSYGPGRYDADY
EECCCCCCHHHHHHHHHHHCCCEEEEEECCCEECCCHHHCEEEEEEEEECCCCCCCCCCC
EDKGNDYPYAFVRWTEQRNFEAILDMMSSGQVDVKPLITHRFKFEDAAQAYDLLTSDKSA
CCCCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEHHHHHEECCCHHHHHHHHHCCCCCC
LGILLQYQSEPSTRHQKSVTLNSKATFEVSKPVVGFVGAGNYASRMLIPAFKAGGAQLHT
EEEEEEECCCCCCCCCCEEEECCCEEEEECCCEEEEEECCCHHHHEEEEHHCCCCCEEEE
IATSGGINGVTHGEKAGFAKTTTDTSAMISDPEINTVAIVTRHNSHARFVCEALNAGKNV
EEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEECCCCHHHHHHHHCCCCCE
FVEKPLAVTLEELAEVEATYYSKASNASEPKLMVGFNRRFSPQVQKMKALLSSVKEPKSF
EEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCE
MMTMNAGAIPADHWTQDNEVGGGRIIGEACHFIDLMRYLADSEIVSVQCRRMGDVSGVDI
EEEECCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCCCEE
TEDKAAIILGFVDGSFGTIHYLANGAANFPKERVEVFAAGRVLQLDNFRKLKGFGWPGFS
CCCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHCCCEEEECCCHHHCCCCCCCCC
KMNLWKQDKGQTNCAAAFLSAIESGKESPIPARELFEVARVTIEIADQLRKQQ
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]