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The map label for this gene is 37678496

Identifier: 37678496

GI number: 37678496

Start: 321524

End: 322597

Strand: Direct

Name: 37678496

Synonym: VV0312

Alternate gene names: NA

Gene position: 321524-322597 (Clockwise)

Preceding gene: 37678495

Following gene: 37678497

Centisome position: 9.58

GC content: 49.16

Gene sequence:

>1074_bases
ATGACTCTAATCATTGCAGAAGCGGGTGTAAACCATAATGGCGACGAAGCACTGGCGTTTAAACTCGTCGACGCTGCGCA
TCAAGCTGGTGCCGATATTGTTAAGTTTCAAACCTTTAAAGCCAAAAACTTAGTGACAGAACAAGCCAAGCAAGCGGATT
ACCAAGTGGCCAATACGCAAAAGCAAGAGTCGCAGCTAGCCATGCTTAGCCGACTTGAGCTGTCTTACGCGGCTCACCAC
CAGTTAGTCAAACATTGTGAGTCACTGGGTATTGAGTTCCTTTCGACCGCTTTTGATTCTGAAAGCTTAGATTTCCTCGT
TAATGATCTTGGTTTAACGCGACTGAAATTGCCTTCTGGTGAGTTGACCAATGCGCCATTAGTCCTTGAGCATGCGCGCA
CAGGATGTGATTTAATCGTGTCTACGGGGATGGCGACACTGGCCGAGATTGAAATGGCATTGGGCGTCATCGCTTTTGGC
TACACTGCAGCGGATCACGTTGCACCGTCGGTATTGGCTTTTCAGCAAGCTTACGCATCAAATGAAGGGCAGAAAGCTCT
GAAAGAGAAAGTGACCATCCTGCACTGCACCACCGAATACCCAGCCCCGATGGCAGAAATTAATCTGAAAGCGATGGATA
CGCTCGGCAAGGCGTTTGATTTACCTGCGGGTTACTCTGATCACAGCGAAGGGATCACCATACCGATTGCCGCCGTTGCG
CGCGGTGCGGTGTTGATCGAAAAACACTTCACACTGGACAAAAATATGGAAGGGCCAGATCACAAGGCATCACTTGAACC
TGATGAACTTACCGCGATGGTGAAGGCCATCCGTCAGGTTGAGTTGGCGCTAGGATCAGCAGTGAAATCTCCAACCGTCT
CTGAAGTCAAAAACAAAGCGGTGGCACGCAAAAGCCTGGTGGCAAGTCAAGCGATTCAAGCAGGCGATGCCTTTAGTGCA
GATAACGTGACGATTAAGCGCCCGGGTAATGGCATGTCTCCTTATCAGTATTGGGAGATGCTCGAGCGTAAAGCAAGCCG
AGATTACCAAATCGGAGATTTGATCCTTGAATAA

Upstream 100 bases:

>100_bases
TGATAGCAGTGCGCAAGTGATTGCAATGATAAAATCACTTCATTTTGAACCTTGTAAGTCATTCTATGACTTACCCTTTG
AACCGATTGAGTGAGGCAGC

Downstream 100 bases:

>100_bases
ACCGTTACCGCTTGTTTTGATTGGAGGAGGCGGGCACGCCAGTGTTTTGGCTGATATCTTACTTGGCCAAGGACGAGAAA
TACTTGCCGTCATTTGCCCT

Product: sialic acid synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MTLIIAEAGVNHNGDEALAFKLVDAAHQAGADIVKFQTFKAKNLVTEQAKQADYQVANTQKQESQLAMLSRLELSYAAHH
QLVKHCESLGIEFLSTAFDSESLDFLVNDLGLTRLKLPSGELTNAPLVLEHARTGCDLIVSTGMATLAEIEMALGVIAFG
YTAADHVAPSVLAFQQAYASNEGQKALKEKVTILHCTTEYPAPMAEINLKAMDTLGKAFDLPAGYSDHSEGITIPIAAVA
RGAVLIEKHFTLDKNMEGPDHKASLEPDELTAMVKAIRQVELALGSAVKSPTVSEVKNKAVARKSLVASQAIQAGDAFSA
DNVTIKRPGNGMSPYQYWEMLERKASRDYQIGDLILE

Sequences:

>Translated_357_residues
MTLIIAEAGVNHNGDEALAFKLVDAAHQAGADIVKFQTFKAKNLVTEQAKQADYQVANTQKQESQLAMLSRLELSYAAHH
QLVKHCESLGIEFLSTAFDSESLDFLVNDLGLTRLKLPSGELTNAPLVLEHARTGCDLIVSTGMATLAEIEMALGVIAFG
YTAADHVAPSVLAFQQAYASNEGQKALKEKVTILHCTTEYPAPMAEINLKAMDTLGKAFDLPAGYSDHSEGITIPIAAVA
RGAVLIEKHFTLDKNMEGPDHKASLEPDELTAMVKAIRQVELALGSAVKSPTVSEVKNKAVARKSLVASQAIQAGDAFSA
DNVTIKRPGNGMSPYQYWEMLERKASRDYQIGDLILE
>Mature_356_residues
TLIIAEAGVNHNGDEALAFKLVDAAHQAGADIVKFQTFKAKNLVTEQAKQADYQVANTQKQESQLAMLSRLELSYAAHHQ
LVKHCESLGIEFLSTAFDSESLDFLVNDLGLTRLKLPSGELTNAPLVLEHARTGCDLIVSTGMATLAEIEMALGVIAFGY
TAADHVAPSVLAFQQAYASNEGQKALKEKVTILHCTTEYPAPMAEINLKAMDTLGKAFDLPAGYSDHSEGITIPIAAVAR
GAVLIEKHFTLDKNMEGPDHKASLEPDELTAMVKAIRQVELALGSAVKSPTVSEVKNKAVARKSLVASQAIQAGDAFSAD
NVTIKRPGNGMSPYQYWEMLERKASRDYQIGDLILE

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=363, Percent_Identity=30.5785123966942, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21357081, Length=295, Percent_Identity=32.2033898305085, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 38523; Mature: 38392

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLIIAEAGVNHNGDEALAFKLVDAAHQAGADIVKFQTFKAKNLVTEQAKQADYQVANTQ
CEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCH
KQESQLAMLSRLELSYAAHHQLVKHCESLGIEFLSTAFDSESLDFLVNDLGLTRLKLPSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHCCCEEEECCCC
ELTNAPLVLEHARTGCDLIVSTGMATLAEIEMALGVIAFGYTAADHVAPSVLAFQQAYAS
CCCCCCEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
NEGQKALKEKVTILHCTTEYPAPMAEINLKAMDTLGKAFDLPAGYSDHSEGITIPIAAVA
CCHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHH
RGAVLIEKHFTLDKNMEGPDHKASLEPDELTAMVKAIRQVELALGSAVKSPTVSEVKNKA
CCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VARKSLVASQAIQAGDAFSADNVTIKRPGNGMSPYQYWEMLERKASRDYQIGDLILE
HHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHCCC
>Mature Secondary Structure 
TLIIAEAGVNHNGDEALAFKLVDAAHQAGADIVKFQTFKAKNLVTEQAKQADYQVANTQ
EEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCH
KQESQLAMLSRLELSYAAHHQLVKHCESLGIEFLSTAFDSESLDFLVNDLGLTRLKLPSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHCCCEEEECCCC
ELTNAPLVLEHARTGCDLIVSTGMATLAEIEMALGVIAFGYTAADHVAPSVLAFQQAYAS
CCCCCCEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
NEGQKALKEKVTILHCTTEYPAPMAEINLKAMDTLGKAFDLPAGYSDHSEGITIPIAAVA
CCHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHH
RGAVLIEKHFTLDKNMEGPDHKASLEPDELTAMVKAIRQVELALGSAVKSPTVSEVKNKA
CCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VARKSLVASQAIQAGDAFSADNVTIKRPGNGMSPYQYWEMLERKASRDYQIGDLILE
HHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]