Click here to switch to the map view.

The map label for this gene is xerC

Identifier: 37678273

GI number: 37678273

Start: 99962

End: 100930

Strand: Direct

Name: xerC

Synonym: VV0089

Alternate gene names: 37678273

Gene position: 99962-100930 (Clockwise)

Preceding gene: 37678272

Following gene: 37678274

Centisome position: 2.98

GC content: 52.94

Gene sequence:

>969_bases
TTGCCTGGCAATTGCAGCATGACGACAGCGTCAAACACACCACTGCCTAGTGGCCTGAGAAAGCCGCTTGATCAGTTCTA
TGAGTACTTGCGTGCGGAGAAAGGCTTAAGCCTGCACACCCAGCGCAACTACAAGCAGCAACTGGAAACCATGGCGGAAC
ACTTACACAGCATGGGGCTCAAAGCGTGGCCGCAAGTGGACGCGGGTTGGGTGCGCCAATTGGCGGGCAAAGGGATGCGT
GAAGGGATGAAGGCAAGCAGCATCGCGACGCGTCTGTCTTCGCTGCGCAGCTTCTTTGACTTTTTGATTTTGCGTGGCAT
CCTCACGGCCAATCCAGCCAAAGGGGTTTCGGCTCCGCGCAAAAAACGTCCTCTGCCCAAAAATCTCGATGTTGATGAAG
TGAATCAACTGCTCGAAGTGAATGAGGATGATCCGCTGGCCATTCGTGATCGCGCCATTATGGAGCTGATGTACGGTGCG
GGATTGCGCTTGGCCGAATTGGTCGATATCGATGTCCGTGATGTGCATTTGCGCAGCGGCGAAATTCGCGTGATCGGTAA
AGGCAACAAAGAACGCAAAGTGCCTTTTGCTGGCATGGCGGTTGAGTGGGTTGGTAAATGGTTAAAAGTGCGCAGTGGTC
TGGCGGACCCAAGTGAGCCGGCGTTGTTTGTCTCGAAGCTGGGCACGCGTATTTCCCATCGCAGTGTGCAAAAGCGCATG
GCCGAATGGGGTCAAAAACAAGCCGTGGCCAGCCATATTACGCCGCACAAACTGCGTCACTCATTTGCTACGCACATTCT
CGAATCGAGCAATAACCTGCGTGCGGTGCAAGAATTACTTGGTCACGAAAACATTTCGACCACGCAAATCTATACGCACC
TCGATTTCCAACACTTGGCCGATGTATATGATCAAGCGCACCCAAGGGCGCGTAAAAAGTCTTCTCAACACAAAGAGGAA
GATGAATGA

Upstream 100 bases:

>100_bases
CTGGCGTTTTCCAGTGCCGACGGTGGTCATTTCCAACCGGAGATGGATACCTTGTTCTTACGTCATCTCTCGTTAGTGGT
GGCCCATTTAGCTCAAACCC

Downstream 100 bases:

>100_bases
AACATTACCGCCCGCTGCAGCCGATCGCGGCAATGACCTTCGACTTAGACGATACCTTGTATGATAACCGTCCGGTGATT
GAACGCTTGGAGCGTGAGGT

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MPGNCSMTTASNTPLPSGLRKPLDQFYEYLRAEKGLSLHTQRNYKQQLETMAEHLHSMGLKAWPQVDAGWVRQLAGKGMR
EGMKASSIATRLSSLRSFFDFLILRGILTANPAKGVSAPRKKRPLPKNLDVDEVNQLLEVNEDDPLAIRDRAIMELMYGA
GLRLAELVDIDVRDVHLRSGEIRVIGKGNKERKVPFAGMAVEWVGKWLKVRSGLADPSEPALFVSKLGTRISHRSVQKRM
AEWGQKQAVASHITPHKLRHSFATHILESSNNLRAVQELLGHENISTTQIYTHLDFQHLADVYDQAHPRARKKSSQHKEE
DE

Sequences:

>Translated_322_residues
MPGNCSMTTASNTPLPSGLRKPLDQFYEYLRAEKGLSLHTQRNYKQQLETMAEHLHSMGLKAWPQVDAGWVRQLAGKGMR
EGMKASSIATRLSSLRSFFDFLILRGILTANPAKGVSAPRKKRPLPKNLDVDEVNQLLEVNEDDPLAIRDRAIMELMYGA
GLRLAELVDIDVRDVHLRSGEIRVIGKGNKERKVPFAGMAVEWVGKWLKVRSGLADPSEPALFVSKLGTRISHRSVQKRM
AEWGQKQAVASHITPHKLRHSFATHILESSNNLRAVQELLGHENISTTQIYTHLDFQHLADVYDQAHPRARKKSSQHKEE
DE
>Mature_321_residues
PGNCSMTTASNTPLPSGLRKPLDQFYEYLRAEKGLSLHTQRNYKQQLETMAEHLHSMGLKAWPQVDAGWVRQLAGKGMRE
GMKASSIATRLSSLRSFFDFLILRGILTANPAKGVSAPRKKRPLPKNLDVDEVNQLLEVNEDDPLAIRDRAIMELMYGAG
LRLAELVDIDVRDVHLRSGEIRVIGKGNKERKVPFAGMAVEWVGKWLKVRSGLADPSEPALFVSKLGTRISHRSVQKRMA
EWGQKQAVASHITPHKLRHSFATHILESSNNLRAVQELLGHENISTTQIYTHLDFQHLADVYDQAHPRARKKSSQHKEED
E

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=296, Percent_Identity=56.4189189189189, Blast_Score=343, Evalue=9e-96,
Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=38.2252559726962, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1790767, Length=196, Percent_Identity=26.0204081632653, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790768, Length=176, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36302; Mature: 36171

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGNCSMTTASNTPLPSGLRKPLDQFYEYLRAEKGLSLHTQRNYKQQLETMAEHLHSMGL
CCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
KAWPQVDAGWVRQLAGKGMREGMKASSIATRLSSLRSFFDFLILRGILTANPAKGVSAPR
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
KKRPLPKNLDVDEVNQLLEVNEDDPLAIRDRAIMELMYGAGLRLAELVDIDVRDVHLRSG
HCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHEEECCC
EIRVIGKGNKERKVPFAGMAVEWVGKWLKVRSGLADPSEPALFVSKLGTRISHRSVQKRM
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AEWGQKQAVASHITPHKLRHSFATHILESSNNLRAVQELLGHENISTTQIYTHLDFQHLA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHH
DVYDQAHPRARKKSSQHKEEDE
HHHHHHCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
PGNCSMTTASNTPLPSGLRKPLDQFYEYLRAEKGLSLHTQRNYKQQLETMAEHLHSMGL
CCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCC
KAWPQVDAGWVRQLAGKGMREGMKASSIATRLSSLRSFFDFLILRGILTANPAKGVSAPR
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
KKRPLPKNLDVDEVNQLLEVNEDDPLAIRDRAIMELMYGAGLRLAELVDIDVRDVHLRSG
HCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCHHHEEECCC
EIRVIGKGNKERKVPFAGMAVEWVGKWLKVRSGLADPSEPALFVSKLGTRISHRSVQKRM
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AEWGQKQAVASHITPHKLRHSFATHILESSNNLRAVQELLGHENISTTQIYTHLDFQHLA
HHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHCCHHHHH
DVYDQAHPRARKKSSQHKEEDE
HHHHHHCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA