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The map label for this gene is cobL [H]

Identifier: 37523931

GI number: 37523931

Start: 4597612

End: 4598229

Strand: Reverse

Name: cobL [H]

Synonym: gvip566

Alternate gene names: 37523931

Gene position: 4598229-4597612 (Counterclockwise)

Preceding gene: 37523937

Following gene: 37523928

Centisome position: 98.7

GC content: 65.21

Gene sequence:

>618_bases
TTGAGCGAGAGCGGACCTTCGAGCGGCAGACCCTGGCCCTACGCCTCTCCGGGCATTCCGGACGAGTGGTTCGAGCGCAT
CCCGGGCATTCCCCTCTCGCCGCGGGAGGTGCGGGTGCTGATGCTCTCGCAGTTGCGCCTCAGTTGCCGGCTGCGGTTCT
GGGATATCGGCGCCGGGACCGGAACGCTCCCGGTGGAAGCGGCCTTACTGTGTCCCACCGCCCCGATCGTTGCCATCGAG
CGCGACGAAGAAGTAGCGGAGCTTATCGAGCGCAACTGCCGCAAATTTGGCGTCACCAATGTGCAGGTTGAGCGCGGCAG
TGCCCCCGAATGTCTCGCCGACCTCGCAGACGATCCCGATCGCGTTTGCATCGAAGGGGGAAAAGCTTTGGCCGGTATCT
TGCACTCGGTCTGGCCGCGGCTGAAGGCGGGGGGACGGGTGGTGGCGGTCACTTCCACCCTCGAAGGACTCTACCGGCTC
ACCGAGGGGTTCGCCGAACTGCAGGCGCGTCAGGTGGAGGTGGTGCAGGCGGGCATCTACCGCCTGGAGCGGCGCGGTGC
CCAGCAGGCTTTTATGGCCCTCGATCCTACCTTTGTGCTGAGCGGCGAAAAAATCTAG

Upstream 100 bases:

>100_bases
ACCAATTGAAATATTCCCCAAGGCGGAGGTGAGCGCCCCTCTACCCCGCTCCAGTTCTCATCGGCTAGGGTAGTGGTCGT
TTCCGTTGTCTGGACAATCC

Downstream 100 bases:

>100_bases
GCATCGCGCATCAGTTCGGGGTCGGCGTGTACCTGCACCCCCATCGAACGGATGAGTGCCAGACTTTCCTCGGGGCCGTC
GATGTGCTGGTCTTCGCCGA

Product: precorrin-6B methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MSESGPSSGRPWPYASPGIPDEWFERIPGIPLSPREVRVLMLSQLRLSCRLRFWDIGAGTGTLPVEAALLCPTAPIVAIE
RDEEVAELIERNCRKFGVTNVQVERGSAPECLADLADDPDRVCIEGGKALAGILHSVWPRLKAGGRVVAVTSTLEGLYRL
TEGFAELQARQVEVVQAGIYRLERRGAQQAFMALDPTFVLSGEKI

Sequences:

>Translated_205_residues
MSESGPSSGRPWPYASPGIPDEWFERIPGIPLSPREVRVLMLSQLRLSCRLRFWDIGAGTGTLPVEAALLCPTAPIVAIE
RDEEVAELIERNCRKFGVTNVQVERGSAPECLADLADDPDRVCIEGGKALAGILHSVWPRLKAGGRVVAVTSTLEGLYRL
TEGFAELQARQVEVVQAGIYRLERRGAQQAFMALDPTFVLSGEKI
>Mature_204_residues
SESGPSSGRPWPYASPGIPDEWFERIPGIPLSPREVRVLMLSQLRLSCRLRFWDIGAGTGTLPVEAALLCPTAPIVAIER
DEEVAELIERNCRKFGVTNVQVERGSAPECLADLADDPDRVCIEGGKALAGILHSVWPRLKAGGRVVAVTSTLEGLYRLT
EGFAELQARQVEVVQAGIYRLERRGAQQAFMALDPTFVLSGEKI

Specific function: Probably catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W. Methylation of C-15 would probably be followed by a spontaneous decarboxylation of C-12 [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Archaeal-type CbiT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014008
- InterPro:   IPR010456 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 1.-.-.-

Molecular weight: Translated: 22397; Mature: 22266

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESGPSSGRPWPYASPGIPDEWFERIPGIPLSPREVRVLMLSQLRLSCRLRFWDIGAGT
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCC
GTLPVEAALLCPTAPIVAIERDEEVAELIERNCRKFGVTNVQVERGSAPECLADLADDPD
CCCCHHHHEECCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCC
RVCIEGGKALAGILHSVWPRLKAGGRVVAVTSTLEGLYRLTEGFAELQARQVEVVQAGIY
CEECCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLERRGAQQAFMALDPTFVLSGEKI
HHHHHCHHHHHHHCCCEEEECCCCC
>Mature Secondary Structure 
SESGPSSGRPWPYASPGIPDEWFERIPGIPLSPREVRVLMLSQLRLSCRLRFWDIGAGT
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCC
GTLPVEAALLCPTAPIVAIERDEEVAELIERNCRKFGVTNVQVERGSAPECLADLADDPD
CCCCHHHHEECCCCCEEEEECCHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCC
RVCIEGGKALAGILHSVWPRLKAGGRVVAVTSTLEGLYRLTEGFAELQARQVEVVQAGIY
CEECCCCHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLERRGAQQAFMALDPTFVLSGEKI
HHHHHCHHHHHHHCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA