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The map label for this gene is rpoD1 [H]

Identifier: 37523928

GI number: 37523928

Start: 4594666

End: 4595700

Strand: Reverse

Name: rpoD1 [H]

Synonym: gll4359

Alternate gene names: 37523928

Gene position: 4595700-4594666 (Counterclockwise)

Preceding gene: 37523931

Following gene: 37523925

Centisome position: 98.64

GC content: 63.29

Gene sequence:

>1035_bases
GTGGTGAGAGCGAGGCACCGCGATTCGGAGGAGCAACCCTTTGGCCTTGACGAGGGCAATCTGCCCTCCAGGAGCGAGGC
CCAGGGTAGTGACGACCTGGTCGATCTGTATCTCAACGAGATTGGTCGCATCCCGCGGGTAACCCCCGAGGAAGAAATTC
ATCTGGCCCGCCGCATCCAGGCGAAGCTTGCCATCGACGGGGCGCGCGAGGAGCTGGCGATGCGGCTGGGTCGACCTTCG
CCGGAAGAGGACGTGGCCGCCTTCATGGGTCGCGATCCCAAGGCCCTCATCGAGGCGACCCGCCAGGGGCTGTGGGCGCA
GCGCAAGCTCATCAACGCCAATTTGCGCCTGGTGGTCTCGATCGCCAAAAAATATATCGGTCGCAATGTGCCCTTTCTCG
ATCTCATCCAGGAGGGTAATATCGGCCTGATGCGCGCCACAGAGAAGTTCGACCCTGAAAAGGGCTACCGCTTCTCGACC
TACGCCACCTGGTGGATCCGCCAGAGCATCACCCGCGCTATCGCCAACCAGGCGCGCACGATTCGCCTGCCCATTCACAT
GGTCGAAAAAGTGCGCAAGGTGCGCCGCGAGATGCGCATGGCGACGCTGGAACTGGGCCGGCGGCCGAGCGAGGACGAAC
TCGCTTCCCGTCTGGCGATCAAAGTCAAGAAGCTGCGCACCATTCAAGAAGTCTCCCGCCAGCCGGTGTCCCTCGACATG
CCCGTGGGCAGCGAAGGGGACATTTCACTGGGCGAGATGATCGAGGACGGCACCGCAGAGCGGCCCTTCGACGAACTGGT
GCAAAAGGCGCTGGCAAGCGAACTGTACGCGGCCATGAATGTACTCAAGCCCGTGGAGCGCGAGGTACTCGCCCTGCGCT
TCGGCCTCAAGGGCGAGGAGGGCCTGACCCTGCGCGAGGTGGGCGAGCGCTTTGATCTGACCCGCGAGCGCATCCGGCAA
ATCGAATCGGAAGCGCTGCGCAAGCTGCGGCGCAGCAAGCGCAAGCAGATCCTGCAGCAGTATGTAGGCGGGTGA

Upstream 100 bases:

>100_bases
TATAAAAAATCTTAGCCGATGATCGATTTTCGTTTACAGCCGTTTGCAAGATTTCCTTAATGTTGAGACATCCGGCAGCC
AGACGAGAGGGAGAGGAACG

Downstream 100 bases:

>100_bases
TCCGCCCACGAGGTGGGGATCAGGCTCCAAGCCAGCGGGCGGCGTCCTTGGCGTGGTAGGTCAAGATCAGGTCCGCCCCG
GCGCGTTTCATCGACATCAG

Product: group2 RNA polymerase sigma factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MVRARHRDSEEQPFGLDEGNLPSRSEAQGSDDLVDLYLNEIGRIPRVTPEEEIHLARRIQAKLAIDGAREELAMRLGRPS
PEEDVAAFMGRDPKALIEATRQGLWAQRKLINANLRLVVSIAKKYIGRNVPFLDLIQEGNIGLMRATEKFDPEKGYRFST
YATWWIRQSITRAIANQARTIRLPIHMVEKVRKVRREMRMATLELGRRPSEDELASRLAIKVKKLRTIQEVSRQPVSLDM
PVGSEGDISLGEMIEDGTAERPFDELVQKALASELYAAMNVLKPVEREVLALRFGLKGEEGLTLREVGERFDLTRERIRQ
IESEALRKLRRSKRKQILQQYVGG

Sequences:

>Translated_344_residues
MVRARHRDSEEQPFGLDEGNLPSRSEAQGSDDLVDLYLNEIGRIPRVTPEEEIHLARRIQAKLAIDGAREELAMRLGRPS
PEEDVAAFMGRDPKALIEATRQGLWAQRKLINANLRLVVSIAKKYIGRNVPFLDLIQEGNIGLMRATEKFDPEKGYRFST
YATWWIRQSITRAIANQARTIRLPIHMVEKVRKVRREMRMATLELGRRPSEDELASRLAIKVKKLRTIQEVSRQPVSLDM
PVGSEGDISLGEMIEDGTAERPFDELVQKALASELYAAMNVLKPVEREVLALRFGLKGEEGLTLREVGERFDLTRERIRQ
IESEALRKLRRSKRKQILQQYVGG
>Mature_344_residues
MVRARHRDSEEQPFGLDEGNLPSRSEAQGSDDLVDLYLNEIGRIPRVTPEEEIHLARRIQAKLAIDGAREELAMRLGRPS
PEEDVAAFMGRDPKALIEATRQGLWAQRKLINANLRLVVSIAKKYIGRNVPFLDLIQEGNIGLMRATEKFDPEKGYRFST
YATWWIRQSITRAIANQARTIRLPIHMVEKVRKVRREMRMATLELGRRPSEDELASRLAIKVKKLRTIQEVSRQPVSLDM
PVGSEGDISLGEMIEDGTAERPFDELVQKALASELYAAMNVLKPVEREVLALRFGLKGEEGLTLREVGERFDLTRERIRQ
IESEALRKLRRSKRKQILQQYVGG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium [H]

COG id: COG0568

COG function: function code K; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1789448, Length=237, Percent_Identity=49.3670886075949, Blast_Score=252, Evalue=3e-68,
Organism=Escherichia coli, GI1789098, Length=315, Percent_Identity=39.6825396825397, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1789871, Length=242, Percent_Identity=31.8181818181818, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788231, Length=205, Percent_Identity=30.2439024390244, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: 700 (log & stationary phase) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR009042
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR012760
- InterPro:   IPR017848
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00140 Sigma70_r1_2; PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 39343; Mature: 39343

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS00716 SIGMA70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRARHRDSEEQPFGLDEGNLPSRSEAQGSDDLVDLYLNEIGRIPRVTPEEEIHLARRIQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
AKLAIDGAREELAMRLGRPSPEEDVAAFMGRDPKALIEATRQGLWAQRKLINANLRLVVS
HHHHHCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IAKKYIGRNVPFLDLIQEGNIGLMRATEKFDPEKGYRFSTYATWWIRQSITRAIANQART
HHHHHHCCCCCHHHHHHCCCCCEEECHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCE
IRLPIHMVEKVRKVRREMRMATLELGRRPSEDELASRLAIKVKKLRTIQEVSRQPVSLDM
EECHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
PVGSEGDISLGEMIEDGTAERPFDELVQKALASELYAAMNVLKPVEREVLALRFGLKGEE
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GLTLREVGERFDLTRERIRQIESEALRKLRRSKRKQILQQYVGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRARHRDSEEQPFGLDEGNLPSRSEAQGSDDLVDLYLNEIGRIPRVTPEEEIHLARRIQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
AKLAIDGAREELAMRLGRPSPEEDVAAFMGRDPKALIEATRQGLWAQRKLINANLRLVVS
HHHHHCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
IAKKYIGRNVPFLDLIQEGNIGLMRATEKFDPEKGYRFSTYATWWIRQSITRAIANQART
HHHHHHCCCCCHHHHHHCCCCCEEECHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCE
IRLPIHMVEKVRKVRREMRMATLELGRRPSEDELASRLAIKVKKLRTIQEVSRQPVSLDM
EECHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
PVGSEGDISLGEMIEDGTAERPFDELVQKALASELYAAMNVLKPVEREVLALRFGLKGEE
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GLTLREVGERFDLTRERIRQIESEALRKLRRSKRKQILQQYVGG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1511015; 1368828 [H]