| Definition | Gloeobacter violaceus PCC 7421 chromosome, complete genome. |
|---|---|
| Accession | NC_005125 |
| Length | 4,659,019 |
Click here to switch to the map view.
The map label for this gene is hdhA [C]
Identifier: 37523772
GI number: 37523772
Start: 4401608
End: 4402348
Strand: Reverse
Name: hdhA [C]
Synonym: gll4203
Alternate gene names: 37523772
Gene position: 4402348-4401608 (Counterclockwise)
Preceding gene: 37523774
Following gene: 37523770
Centisome position: 94.49
GC content: 64.78
Gene sequence:
>741_bases ATGTCTTCGTTGCAAGGAAAGGTGGCCATTGTCACGGGGGCGTCGCGCGGCATCGGCCGGGCCATCGCCGAGGGCCTCGC AAGCAAAGGGGCCTCGGTTGTCGTCAACTACGCGGGCAGCAAGGACAAAGCCCGGGAAGTGGTGCAAACCATCGAGGCGG CGGGTGGGCAGGCGATCGCCGTCCAGGCGGATGTCAGTCGCGTCGAGCAGATCGACGCGCTGTTCGACGAAACGTTTGCG CGCTTCGGGCGGCTCGATATTCTTGTCAACAACGCCGGGTTGTCGATCATGAAGCCGATGGTCGACATTAGCGAAGCGGA ATTCGACAGGCTGTTCACCCTCAACGCCCGGGGGGTGTTCTTTGCTCTGCAGCGGGCCGCCGCGCGCATGGCGGCGGGCG GCCGTATTGTGAGCGTCACCACCGGCGGCACCGCGACCGGTGCCGCCGGCGCCACGGCCTACGCCGGCAGCAAAGCGGCC ATCGAAGGATTCAGTATGTCGCTCTCAAAAGAACTGGGTGCGCGCGGTATCACGGTCAATACGGTCATGCCTGGACCCAC GGATACCGAGATGTTCGAGGCGGCGGCCCCGCTGGAGATGAAAAAAATGGCCGAGCAGATGTCGCCCTTTGGGCGGCTCG GCGAGCCGCGCGATGTGGCCGACGTGGTAATCTTTCTGGCAAGCGAGGAGGCGCGCTGGGTGACCGGACAGCGCATCAGT GCCAGCGGCGGAGCCATTTGA
Upstream 100 bases:
>100_bases CGCCTCCGCCTATCCCGACTTCGACTTACTTTTCGGTAAGTACTTCCATTATCGTAAGCCGCAAAATAGGATGGTGATCG TCAAGAGCGAGGGTTGGCGC
Downstream 100 bases:
>100_bases GCAACTAGCGGGAGACGGCGGCTGCCGGAGCGGCTTCTTCGCTCTCCAGGCGGGCGATGCGCTCGTCGAGCCGGGCGAAG AGCTTAGCCAGACCGCTTGT
Product: dehydrogenase/reductase
Products: 3alpha12alpha-dihydroxy-oxobeta-cholanate; NADH [C]
Alternate protein names: ORFC [H]
Number of amino acids: Translated: 246; Mature: 245
Protein sequence:
>246_residues MSSLQGKVAIVTGASRGIGRAIAEGLASKGASVVVNYAGSKDKAREVVQTIEAAGGQAIAVQADVSRVEQIDALFDETFA RFGRLDILVNNAGLSIMKPMVDISEAEFDRLFTLNARGVFFALQRAAARMAAGGRIVSVTTGGTATGAAGATAYAGSKAA IEGFSMSLSKELGARGITVNTVMPGPTDTEMFEAAAPLEMKKMAEQMSPFGRLGEPRDVADVVIFLASEEARWVTGQRIS ASGGAI
Sequences:
>Translated_246_residues MSSLQGKVAIVTGASRGIGRAIAEGLASKGASVVVNYAGSKDKAREVVQTIEAAGGQAIAVQADVSRVEQIDALFDETFA RFGRLDILVNNAGLSIMKPMVDISEAEFDRLFTLNARGVFFALQRAAARMAAGGRIVSVTTGGTATGAAGATAYAGSKAA IEGFSMSLSKELGARGITVNTVMPGPTDTEMFEAAAPLEMKKMAEQMSPFGRLGEPRDVADVVIFLASEEARWVTGQRIS ASGGAI >Mature_245_residues SSLQGKVAIVTGASRGIGRAIAEGLASKGASVVVNYAGSKDKAREVVQTIEAAGGQAIAVQADVSRVEQIDALFDETFAR FGRLDILVNNAGLSIMKPMVDISEAEFDRLFTLNARGVFFALQRAAARMAAGGRIVSVTTGGTATGAAGATAYAGSKAAI EGFSMSLSKELGARGITVNTVMPGPTDTEMFEAAAPLEMKKMAEQMSPFGRLGEPRDVADVVIFLASEEARWVTGQRISA SGGAI
Specific function: 7-Alpha-Dehydroxylation Of Cholic Acid, Yielding Deoxycholic Acid And Lithocholic Acid, Respectively. Highest Affinity With Taurochenodeoxycholic Acid. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=35.4330708661417, Blast_Score=134, Evalue=8e-32, Organism=Homo sapiens, GI40254992, Length=243, Percent_Identity=32.9218106995885, Blast_Score=107, Evalue=1e-23, Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=32.8, Blast_Score=105, Evalue=4e-23, Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=29.4820717131474, Blast_Score=101, Evalue=6e-22, Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=29.6747967479675, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI31542939, Length=260, Percent_Identity=29.6153846153846, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI59889578, Length=217, Percent_Identity=30.4147465437788, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI5031737, Length=243, Percent_Identity=27.9835390946502, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=30.1204819277108, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=29.3650793650794, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI4504505, Length=238, Percent_Identity=29.8319327731092, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI209862901, Length=200, Percent_Identity=30.5, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI19923983, Length=200, Percent_Identity=30.5, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI4503817, Length=232, Percent_Identity=28.448275862069, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=27.5193798449612, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=28.8537549407115, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI4503301, Length=251, Percent_Identity=29.4820717131474, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI224922801, Length=184, Percent_Identity=32.0652173913043, Blast_Score=76, Evalue=2e-14, Organism=Homo sapiens, GI7657478, Length=198, Percent_Identity=31.8181818181818, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI40254986, Length=192, Percent_Identity=27.6041666666667, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI7706318, Length=205, Percent_Identity=28.780487804878, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI83715985, Length=258, Percent_Identity=26.3565891472868, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI146231950, Length=248, Percent_Identity=26.6129032258064, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI109715829, Length=245, Percent_Identity=26.530612244898, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI40807363, Length=196, Percent_Identity=28.0612244897959, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI310128830, Length=205, Percent_Identity=29.2682926829268, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI310115468, Length=205, Percent_Identity=29.2682926829268, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI186928839, Length=227, Percent_Identity=28.6343612334802, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=30.8108108108108, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI10190746, Length=257, Percent_Identity=27.6264591439689, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI166795268, Length=206, Percent_Identity=30.0970873786408, Blast_Score=68, Evalue=6e-12, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI225579078, Length=207, Percent_Identity=27.536231884058, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI142976729, Length=187, Percent_Identity=28.8770053475936, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI25282469, Length=238, Percent_Identity=24.3697478991597, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=38.3673469387755, Blast_Score=145, Evalue=2e-36, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=37.5510204081633, Blast_Score=142, Evalue=2e-35, Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=38.3966244725738, Blast_Score=142, Evalue=2e-35, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=38.3673469387755, Blast_Score=139, Evalue=2e-34, Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=33.201581027668, Blast_Score=135, Evalue=2e-33, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=34.2857142857143, Blast_Score=129, Evalue=2e-31, Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=28.9156626506024, Blast_Score=119, Evalue=1e-28, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=33.3333333333333, Blast_Score=118, Evalue=4e-28, Organism=Escherichia coli, GI1789378, Length=245, Percent_Identity=31.0204081632653, Blast_Score=117, Evalue=7e-28, Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=30.241935483871, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=31.3725490196078, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=30.46875, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI1787526, Length=247, Percent_Identity=27.9352226720648, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=25.2747252747253, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1786701, Length=197, Percent_Identity=30.4568527918782, Blast_Score=65, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=34.2205323193916, Blast_Score=124, Evalue=3e-29, Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=35.4716981132075, Blast_Score=121, Evalue=3e-28, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=35.361216730038, Blast_Score=120, Evalue=4e-28, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=34.2205323193916, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=32.2448979591837, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=31.3253012048193, Blast_Score=114, Evalue=5e-26, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=34.8484848484849, Blast_Score=113, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=32.6612903225806, Blast_Score=113, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17555706, Length=244, Percent_Identity=34.0163934426229, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=34.5864661654135, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17531453, Length=263, Percent_Identity=32.6996197718631, Blast_Score=110, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17560150, Length=263, Percent_Identity=31.5589353612167, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=33.0798479087452, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=34.375, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=32.5490196078431, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=32.319391634981, Blast_Score=103, Evalue=5e-23, Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=32.0987654320988, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=36.9791666666667, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=33.0739299610895, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=29.0566037735849, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17538480, Length=260, Percent_Identity=32.6923076923077, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=32.183908045977, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=30.0380228136882, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17538182, Length=261, Percent_Identity=31.4176245210728, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17562904, Length=271, Percent_Identity=30.6273062730627, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=32.9457364341085, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=30.6772908366534, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17536025, Length=254, Percent_Identity=30.3149606299213, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=30.6122448979592, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17563726, Length=259, Percent_Identity=27.4131274131274, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=28.4263959390863, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17561272, Length=251, Percent_Identity=31.4741035856574, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI193203115, Length=200, Percent_Identity=29.5, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI193203117, Length=198, Percent_Identity=29.7979797979798, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=28, Blast_Score=80, Evalue=7e-16, Organism=Caenorhabditis elegans, GI71997099, Length=206, Percent_Identity=33.9805825242718, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17555612, Length=210, Percent_Identity=31.4285714285714, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI71982365, Length=189, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17567345, Length=194, Percent_Identity=29.3814432989691, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17558628, Length=190, Percent_Identity=30, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI86565303, Length=210, Percent_Identity=29.0476190476191, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=244, Percent_Identity=29.9180327868852, Blast_Score=90, Evalue=3e-19, Organism=Saccharomyces cerevisiae, GI6324126, Length=246, Percent_Identity=26.4227642276423, Blast_Score=76, Evalue=4e-15, Organism=Saccharomyces cerevisiae, GI6322227, Length=200, Percent_Identity=27.5, Blast_Score=74, Evalue=2e-14, Organism=Saccharomyces cerevisiae, GI6322226, Length=224, Percent_Identity=29.0178571428571, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=241, Percent_Identity=28.6307053941909, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322067, Length=191, Percent_Identity=30.3664921465969, Blast_Score=63, Evalue=4e-11, Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=35.3658536585366, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=35.4330708661417, Blast_Score=126, Evalue=1e-29, Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=33.8645418326693, Blast_Score=124, Evalue=8e-29, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=33.469387755102, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=34.251968503937, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=29.7959183673469, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=33.4661354581673, Blast_Score=111, Evalue=3e-25, Organism=Drosophila melanogaster, GI17737361, Length=235, Percent_Identity=32.7659574468085, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI24644337, Length=250, Percent_Identity=30.8, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI18859837, Length=240, Percent_Identity=30.8333333333333, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI24641232, Length=207, Percent_Identity=32.8502415458937, Blast_Score=84, Evalue=7e-17, Organism=Drosophila melanogaster, GI281364892, Length=194, Percent_Identity=28.3505154639175, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI24640492, Length=195, Percent_Identity=24.6153846153846, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI24580925, Length=208, Percent_Identity=31.25, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI24656154, Length=213, Percent_Identity=30.0469483568075, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI19922628, Length=213, Percent_Identity=30.0469483568075, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI21357673, Length=244, Percent_Identity=26.2295081967213, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24581726, Length=227, Percent_Identity=26.8722466960352, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI28571387, Length=241, Percent_Identity=28.2157676348548, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI116007236, Length=241, Percent_Identity=26.5560165975104, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI116007234, Length=209, Percent_Identity=29.1866028708134, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI24649181, Length=191, Percent_Identity=28.7958115183246, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI21355631, Length=169, Percent_Identity=31.3609467455621, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI22024069, Length=206, Percent_Identity=30.0970873786408, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI28573296, Length=203, Percent_Identity=30.5418719211823, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI161076371, Length=207, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI281364494, Length=238, Percent_Identity=27.3109243697479, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI21356301, Length=208, Percent_Identity=27.4038461538462, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24648693, Length=209, Percent_Identity=30.1435406698565, Blast_Score=64, Evalue=6e-11, Organism=Drosophila melanogaster, GI21355889, Length=209, Percent_Identity=30.1435406698565, Blast_Score=64, Evalue=6e-11, Organism=Drosophila melanogaster, GI221331218, Length=198, Percent_Identity=28.2828282828283, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.159 [C]
Molecular weight: Translated: 25438; Mature: 25307
Theoretical pI: Translated: 5.44; Mature: 5.44
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 4.1 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSSLQGKVAIVTGASRGIGRAIAEGLASKGASVVVNYAGSKDKAREVVQTIEAAGGQAIA CCCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEE VQADVSRVEQIDALFDETFARFGRLDILVNNAGLSIMKPMVDISEAEFDRLFTLNARGVF EEHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCHHCCCEEEEECCCHHH FALQRAAARMAAGGRIVSVTTGGTATGAAGATAYAGSKAAIEGFSMSLSKELGARGITVN HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCEEEE TVMPGPTDTEMFEAAAPLEMKKMAEQMSPFGRLGEPRDVADVVIFLASEEARWVTGQRIS EECCCCCCHHHHHHCCCHHHHHHHHHHCHHHCCCCCCCHHHEEEEEECCCCCEECCCEEC ASGGAI CCCCCC >Mature Secondary Structure SSLQGKVAIVTGASRGIGRAIAEGLASKGASVVVNYAGSKDKAREVVQTIEAAGGQAIA CCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEE VQADVSRVEQIDALFDETFARFGRLDILVNNAGLSIMKPMVDISEAEFDRLFTLNARGVF EEHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCHHCCCEEEEECCCHHH FALQRAAARMAAGGRIVSVTTGGTATGAAGATAYAGSKAAIEGFSMSLSKELGARGITVN HHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCEEEE TVMPGPTDTEMFEAAAPLEMKKMAEQMSPFGRLGEPRDVADVVIFLASEEARWVTGQRIS EECCCCCCHHHHHHCCCHHHHHHHHHHCHHHCCCCCCCHHHEEEEEECCCCCEECCCEEC ASGGAI CCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: 2-Mercaptoethanol; Dithiothreitol; NAD+; NADH [C]
Metal ions: CaCl2; KCl; MnCl2; NaCl [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.8 {cholic} 0.085 {glycochenodeoxycholic} 0.24 {taurochenodeoxycholic} 1 {glycocholic} 0.06 {chenodeoxycholic} [C]
Substrates: @ALPH01.txt*3alpha7alpha12alpha-Trihydroxybeta-cholanate!; NAD [C]
Specific reaction: @ALPH01.txt*3alpha7alpha12alpha-Trihydroxybeta-cholanate! + NAD+ = 3alpha12alpha-dihydroxy-oxobeta-cholanate + NADH [C]
General reaction: Redox reaction [C]
Inhibitor: Ascorbicacid; BaCl2; CoCl2; CuCl2; EDTA; FeCl3; HgCl2; MgCl2; NH4Cl; Potassiumoxalate; Sodiumcitrate; Sodiumlaurylsulfate; Sodiumperchlorate; Sodiumperiodate; Sodiumpersulfate; TritonX-100; Tween; ZnCl2 [C]
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8868443 [H]