Click here to switch to the map view.

The map label for this gene is yycG [H]

Identifier: 37523730

GI number: 37523730

Start: 4359536

End: 4360564

Strand: Reverse

Name: yycG [H]

Synonym: gll4161

Alternate gene names: 37523730

Gene position: 4360564-4359536 (Counterclockwise)

Preceding gene: 37523731

Following gene: 37523729

Centisome position: 93.59

GC content: 61.81

Gene sequence:

>1029_bases
ATGCTTGCTGAACAAGAAATTCTGGATTGTCTTCCTTTCGGACTGGTTGTAACCGACCGGGAGGGCCGTGTCCTCCTGTG
GAACGATGCGATGGAAAGCCTGACAGGGACGAAGGCTGCCGATGTGCAGGGTGGGTGGATCCAATGTTGGTCGGCGGAAG
TGGCCGAGATCGGTACCCAGGGCCACGTTTTTTTGCGCAACGGCGAGGAACAGAGCTTCAGCCTCAGCGTGCGCACCGCC
GTCAGCCGCGAGGGACATCGGGTATGGGTGTTCATTCCCGACAGCCGCCAAGAGCTGGATCAGGCCCAAACCGACTTTGT
CTCGACCGTTTCCCACGAACTGCGCACGCCGCTCACCAGCATCAAAGGTTTTGTCGACACGCTCCTGCGCTCGGGATCGC
AGCTGAGCGAAGCGCAGCACCGCCGGTTTTTGCGCATCATCAAAAACCAGGCCGACCGGCTCACCCGTCTGGTCGAGGAC
ATTCTCACCGTCTCGCGCATCCAGTCGGGGCGGCTCAAGAATTTGCCCCAGAGGCTGGATTTGGGAGAAATGATCGACCG
CGTCTTCGAGAATCTGGCGCAAAAGTACGCAGCGCAACGCATGCGCCGGGAGTTGCCCGGCGCCCTGCCTGAGGTCTGGG
CCGATCAAGACCGCCTGGAGCAGATTCTCACCAACTTGATCGACAACGCCCTCAAGTACTCCGAACACGGTGCGCCGGTG
TGCGTGAGCGCCGATCTCGACCCGGAAGATCGCAATGTGCTCTGGATTGCCGTGCGCGACCTGGGCATCGGCATTCCCGA
AGAGAACCTCGACCAGATCTTCAACCGCTTCAGCCGCATCGACTCGCCCCTCACCCGCGAGCGCGAGGGTACGGGGCTCG
GGCTTTATATTACCAAGTCCTTGGTCGAGAGTCTGGGGGGCACCATCCACGTCGAGAGCCGCTACGGGGTGGGCAGCACC
TTCACGGTGAGCCTGCCCGCCGTCCAGGCCGGGGCGATCGAACCGGGCGAGGAAGGTTGGCATGCCTGA

Upstream 100 bases:

>100_bases
TACACTGTTGAAGGCGTGGCGCCACCCGATGGGTGGCGCCAGTCTTTAGTTTTTTTTTCGCACGCTTTGTCGGCGCCCCA
TGCTACTCAATGATGGCTAG

Downstream 100 bases:

>100_bases
GCAGCGCGAACAGCGATTGCCTGAACTTTTGGGGTCGGCCGAGAACGCACTGCTCGACCAGTTTTTGCACTGCGGGGACT
GGGCGCTTTTGTATGTCGAC

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MLAEQEILDCLPFGLVVTDREGRVLLWNDAMESLTGTKAADVQGGWIQCWSAEVAEIGTQGHVFLRNGEEQSFSLSVRTA
VSREGHRVWVFIPDSRQELDQAQTDFVSTVSHELRTPLTSIKGFVDTLLRSGSQLSEAQHRRFLRIIKNQADRLTRLVED
ILTVSRIQSGRLKNLPQRLDLGEMIDRVFENLAQKYAAQRMRRELPGALPEVWADQDRLEQILTNLIDNALKYSEHGAPV
CVSADLDPEDRNVLWIAVRDLGIGIPEENLDQIFNRFSRIDSPLTREREGTGLGLYITKSLVESLGGTIHVESRYGVGST
FTVSLPAVQAGAIEPGEEGWHA

Sequences:

>Translated_342_residues
MLAEQEILDCLPFGLVVTDREGRVLLWNDAMESLTGTKAADVQGGWIQCWSAEVAEIGTQGHVFLRNGEEQSFSLSVRTA
VSREGHRVWVFIPDSRQELDQAQTDFVSTVSHELRTPLTSIKGFVDTLLRSGSQLSEAQHRRFLRIIKNQADRLTRLVED
ILTVSRIQSGRLKNLPQRLDLGEMIDRVFENLAQKYAAQRMRRELPGALPEVWADQDRLEQILTNLIDNALKYSEHGAPV
CVSADLDPEDRNVLWIAVRDLGIGIPEENLDQIFNRFSRIDSPLTREREGTGLGLYITKSLVESLGGTIHVESRYGVGST
FTVSLPAVQAGAIEPGEEGWHA
>Mature_342_residues
MLAEQEILDCLPFGLVVTDREGRVLLWNDAMESLTGTKAADVQGGWIQCWSAEVAEIGTQGHVFLRNGEEQSFSLSVRTA
VSREGHRVWVFIPDSRQELDQAQTDFVSTVSHELRTPLTSIKGFVDTLLRSGSQLSEAQHRRFLRIIKNQADRLTRLVED
ILTVSRIQSGRLKNLPQRLDLGEMIDRVFENLAQKYAAQRMRRELPGALPEVWADQDRLEQILTNLIDNALKYSEHGAPV
CVSADLDPEDRNVLWIAVRDLGIGIPEENLDQIFNRFSRIDSPLTREREGTGLGLYITKSLVESLGGTIHVESRYGVGST
FTVSLPAVQAGAIEPGEEGWHA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=230, Percent_Identity=33.4782608695652, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI145693157, Length=251, Percent_Identity=33.8645418326693, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI48994928, Length=239, Percent_Identity=35.9832635983264, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=33.8983050847458, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=35.042735042735, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786600, Length=232, Percent_Identity=30.6034482758621, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=31.9327731092437, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=28.695652173913, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786783, Length=231, Percent_Identity=27.7056277056277, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87081816, Length=290, Percent_Identity=28.9655172413793, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788549, Length=342, Percent_Identity=27.1929824561404, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=32.3275862068966, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790861, Length=204, Percent_Identity=28.921568627451, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1790300, Length=260, Percent_Identity=27.6923076923077, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=23.1441048034935, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788279, Length=228, Percent_Identity=28.0701754385965, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787894, Length=235, Percent_Identity=26.8085106382979, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38270; Mature: 38270

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAEQEILDCLPFGLVVTDREGRVLLWNDAMESLTGTKAADVQGGWIQCWSAEVAEIGTQ
CCCHHHHHHHCCCCEEEECCCCCEEEECHHHHHHCCCCCCCCCCCCEEEHHHHHHHCCCC
GHVFLRNGEEQSFSLSVRTAVSREGHRVWVFIPDSRQELDQAQTDFVSTVSHELRTPLTS
CEEEEECCCCCCEEEEEHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCHHHH
IKGFVDTLLRSGSQLSEAQHRRFLRIIKNQADRLTRLVEDILTVSRIQSGRLKNLPQRLD
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHCCC
LGEMIDRVFENLAQKYAAQRMRRELPGALPEVWADQDRLEQILTNLIDNALKYSEHGAPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCE
CVSADLDPEDRNVLWIAVRDLGIGIPEENLDQIFNRFSRIDSPLTREREGTGLGLYITKS
EEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCEEHHHHHH
LVESLGGTIHVESRYGVGSTFTVSLPAVQAGAIEPGEEGWHA
HHHHCCCEEEEEECCCCCCEEEEECCCEECCCCCCCCCCCCC
>Mature Secondary Structure
MLAEQEILDCLPFGLVVTDREGRVLLWNDAMESLTGTKAADVQGGWIQCWSAEVAEIGTQ
CCCHHHHHHHCCCCEEEECCCCCEEEECHHHHHHCCCCCCCCCCCCEEEHHHHHHHCCCC
GHVFLRNGEEQSFSLSVRTAVSREGHRVWVFIPDSRQELDQAQTDFVSTVSHELRTPLTS
CEEEEECCCCCCEEEEEHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCHHHH
IKGFVDTLLRSGSQLSEAQHRRFLRIIKNQADRLTRLVEDILTVSRIQSGRLKNLPQRLD
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHCCC
LGEMIDRVFENLAQKYAAQRMRRELPGALPEVWADQDRLEQILTNLIDNALKYSEHGAPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCE
CVSADLDPEDRNVLWIAVRDLGIGIPEENLDQIFNRFSRIDSPLTREREGTGLGLYITKS
EEECCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCEEHHHHHH
LVESLGGTIHVESRYGVGSTFTVSLPAVQAGAIEPGEEGWHA
HHHHCCCEEEEEECCCCCCEEEEECCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]