BacMap

Definition	Gloeobacter violaceus PCC 7421 chromosome, complete genome.
Accession	NC_005125
Length	4,659,019

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The map label for this gene is spkD [H]

Identifier: 37523676

GI number: 37523676

Start: 4302668

End: 4303540

Strand: Direct

Name: spkD [H]

Synonym: glr4107

Alternate gene names: 37523676

Gene position: 4302668-4303540 (Clockwise)

Preceding gene: 37523675

Following gene: 37523677

Centisome position: 92.35

GC content: 65.86

Gene sequence:

>873_bases
GTGGCCAGGAGCAAGGTGCCCTCAGAGTGCTGCGAACGGCATGGCGGCCTGACGCGCTTTTGCCCGGTCTGCGGCCGCTT
GCTCGCAGGCGGCGAAGTGCTCGAAAATCCGGAGAGCGGCCACCGCTACGAGCGGGTCGCCACCCTCGCCCAGGGGGGCA
TGAGCACGACTTATCTGGTCTTCAACCATCAGAACGACCGGCTTGCGGTGCTCAAGGAAATCGACGCGGATCTCTCGCGC
AAGGCCAAAGCGCGCGAACTATTTTTGCGCGAGGCGCAGGTGCTCGCAGAACTCGACCACGGCGGCATCCCCCGCTTTTA
CGACTATTTTTCCAGCGACGAACGCCATTATTTGGTCATGGAGATGATCCACGGCCTCACCCTTGAGCAGGTGCAGCCCC
GTTCCGCCGCCCAGGCGGCAGGCTGGATGATCGAAGCGTGCAACGTGCTGGTCTACCTGCACGGCTTGCAACCGCCGGTC
ATCCACCGCGACATCAAGCCCGCCAATTTGATCTTGCGCTACAACCCCCGCGAGGTGGTGCTCATCGACTACGGCGCGGT
CAAGTTGGCCGGCGGCAGGCAGGGCACGCGCATCGCCACCCCCGGCTACAGCCCGCCGGAGCAGGGGCGGGGACGGCCCT
GCCTGCAGTCGGATATCTACGGTGTCGGGATGACGCTGGTATTTTTGCTCACCCGCCAGTTTCCGGGCCGCTTCTACCAC
CCGCGCGAGCGGCGGCTGGTGGGTCTGGAGGAAGCCGGAATCGAAGCGCCGCTCGCGGCGGTGATCGCCAAGGCCACCGC
CTACCTCCCCCAGGAGCGCCACCGCGACAGCCAGGAGTTGGCCCATGCCCTGGCGCCCTTTGCCCTGGGTTGA

Upstream 100 bases:

>100_bases
GAAGTCGGTGCAGCGCCCTGGCGGTTTGTCCCCTTTACATTTACACGGGGGTAAACCGTCCCCCCCTTAGAACCCGCATC
GTTGTGTCAAAGGAGCAAGC

Downstream 100 bases:

>100_bases
GCGACTCGGTACAATAGCGCAGTCCGTTTGCCGTTGGTGCCCATGAAGACTGCCGCCCGCCTCGATCGCATCCCGCCTTA
TCTGTTTGCCGAAATCGACC

Product: serine/threonine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MARSKVPSECCERHGGLTRFCPVCGRLLAGGEVLENPESGHRYERVATLAQGGMSTTYLVFNHQNDRLAVLKEIDADLSR
KAKARELFLREAQVLAELDHGGIPRFYDYFSSDERHYLVMEMIHGLTLEQVQPRSAAQAAGWMIEACNVLVYLHGLQPPV
IHRDIKPANLILRYNPREVVLIDYGAVKLAGGRQGTRIATPGYSPPEQGRGRPCLQSDIYGVGMTLVFLLTRQFPGRFYH
PRERRLVGLEEAGIEAPLAAVIAKATAYLPQERHRDSQELAHALAPFALG

Sequences:

>Translated_290_residues
MARSKVPSECCERHGGLTRFCPVCGRLLAGGEVLENPESGHRYERVATLAQGGMSTTYLVFNHQNDRLAVLKEIDADLSR
KAKARELFLREAQVLAELDHGGIPRFYDYFSSDERHYLVMEMIHGLTLEQVQPRSAAQAAGWMIEACNVLVYLHGLQPPV
IHRDIKPANLILRYNPREVVLIDYGAVKLAGGRQGTRIATPGYSPPEQGRGRPCLQSDIYGVGMTLVFLLTRQFPGRFYH
PRERRLVGLEEAGIEAPLAAVIAKATAYLPQERHRDSQELAHALAPFALG
>Mature_289_residues
ARSKVPSECCERHGGLTRFCPVCGRLLAGGEVLENPESGHRYERVATLAQGGMSTTYLVFNHQNDRLAVLKEIDADLSRK
AKARELFLREAQVLAELDHGGIPRFYDYFSSDERHYLVMEMIHGLTLEQVQPRSAAQAAGWMIEACNVLVYLHGLQPPVI
HRDIKPANLILRYNPREVVLIDYGAVKLAGGRQGTRIATPGYSPPEQGRGRPCLQSDIYGVGMTLVFLLTRQFPGRFYHP
RERRLVGLEEAGIEAPLAAVIAKATAYLPQERHRDSQELAHALAPFALG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI83627721, Length=204, Percent_Identity=26.9607843137255, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI30039692, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI211971038, Length=271, Percent_Identity=26.9372693726937, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI211971036, Length=271, Percent_Identity=26.9372693726937, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI33636698, Length=271, Percent_Identity=26.9372693726937, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI45643117, Length=272, Percent_Identity=25.7352941176471, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI162951881, Length=272, Percent_Identity=25.7352941176471, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI14196445, Length=254, Percent_Identity=26.7716535433071, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI62865643, Length=245, Percent_Identity=28.9795918367347, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI62865639, Length=245, Percent_Identity=28.9795918367347, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI62865641, Length=245, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI38327572, Length=182, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI38327570, Length=182, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI38327568, Length=182, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI38327566, Length=182, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI38327564, Length=182, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI38327562, Length=182, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI5579478, Length=200, Percent_Identity=29.5, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI225735561, Length=205, Percent_Identity=27.8048780487805, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI41872673, Length=201, Percent_Identity=29.3532338308458, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI93004081, Length=259, Percent_Identity=25.8687258687259, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI121114283, Length=214, Percent_Identity=26.6355140186916, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI26051216, Length=185, Percent_Identity=31.3513513513514, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI26051212, Length=185, Percent_Identity=31.3513513513514, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI26051206, Length=190, Percent_Identity=31.5789473684211, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI26051210, Length=185, Percent_Identity=31.3513513513514, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI26051214, Length=185, Percent_Identity=31.3513513513514, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI26051208, Length=185, Percent_Identity=31.3513513513514, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI83776600, Length=245, Percent_Identity=29.3877551020408, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI26051218, Length=185, Percent_Identity=31.3513513513514, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI15619015, Length=217, Percent_Identity=27.1889400921659, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI13489054, Length=201, Percent_Identity=29.8507462686567, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI25952114, Length=182, Percent_Identity=31.3186813186813, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI26051204, Length=190, Percent_Identity=31.0526315789474, Blast_Score=65, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71994328, Length=258, Percent_Identity=28.6821705426357, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193208795, Length=218, Percent_Identity=27.5229357798165, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193208793, Length=218, Percent_Identity=27.5229357798165, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17541716, Length=196, Percent_Identity=29.5918367346939, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71981762, Length=211, Percent_Identity=27.9620853080569, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25153836, Length=204, Percent_Identity=25.9803921568627, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71984736, Length=162, Percent_Identity=30.8641975308642, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71984730, Length=162, Percent_Identity=30.8641975308642, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17510519, Length=206, Percent_Identity=25.7281553398058, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71991037, Length=211, Percent_Identity=25.5924170616114, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193207933, Length=269, Percent_Identity=25.6505576208178, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17566666, Length=242, Percent_Identity=26.8595041322314, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322682, Length=291, Percent_Identity=24.7422680412371, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324805, Length=220, Percent_Identity=29.5454545454545, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325047, Length=220, Percent_Identity=25.9090909090909, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319328, Length=214, Percent_Identity=26.6355140186916, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648518, Length=153, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17136516, Length=248, Percent_Identity=26.2096774193548, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17647993, Length=178, Percent_Identity=28.6516853932584, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281359587, Length=190, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI62484414, Length=190, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281359589, Length=190, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI62484416, Length=190, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24638772, Length=190, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281359585, Length=190, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45549243, Length=190, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45551188, Length=190, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI62473187, Length=190, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI62472270, Length=202, Percent_Identity=25.2475247524752, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24667346, Length=202, Percent_Identity=25.2475247524752, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358073, Length=221, Percent_Identity=28.9592760180996, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI18858209, Length=197, Percent_Identity=29.9492385786802, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF00069 Pkinase; PF08239 SH3_3 [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 32280; Mature: 32148

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS00108 PROTEIN_KINASE_ST ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSKVPSECCERHGGLTRFCPVCGRLLAGGEVLENPESGHRYERVATLAQGGMSTTYLV
CCCCCCCHHHHHHCCCCHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHCCCCEEEEE
FNHQNDRLAVLKEIDADLSRKAKARELFLREAQVLAELDHGGIPRFYDYFSSDERHYLVM
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEHHH
EMIHGLTLEQVQPRSAAQAAGWMIEACNVLVYLHGLQPPVIHRDIKPANLILRYNPREVV
HHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHCCCCCCCEEEEEECCCEEE
LIDYGAVKLAGGRQGTRIATPGYSPPEQGRGRPCLQSDIYGVGMTLVFLLTRQFPGRFYH
EEECCEEEECCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PRERRLVGLEEAGIEAPLAAVIAKATAYLPQERHRDSQELAHALAPFALG
CHHHCEECHHHCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
ARSKVPSECCERHGGLTRFCPVCGRLLAGGEVLENPESGHRYERVATLAQGGMSTTYLV
CCCCCCHHHHHHCCCCHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHCCCCEEEEE
FNHQNDRLAVLKEIDADLSRKAKARELFLREAQVLAELDHGGIPRFYDYFSSDERHYLVM
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEHHH
EMIHGLTLEQVQPRSAAQAAGWMIEACNVLVYLHGLQPPVIHRDIKPANLILRYNPREVV
HHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCHHCCCCCCCEEEEEECCCEEE
LIDYGAVKLAGGRQGTRIATPGYSPPEQGRGRPCLQSDIYGVGMTLVFLLTRQFPGRFYH
EEECCEEEECCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
PRERRLVGLEEAGIEAPLAAVIAKATAYLPQERHRDSQELAHALAPFALG
CHHHCEECHHHCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12168951; 8590279; 8905231 [H]