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The map label for this gene is dhaR [H]

Identifier: 37523395

GI number: 37523395

Start: 4031095

End: 4031718

Strand: Reverse

Name: dhaR [H]

Synonym: gll3826

Alternate gene names: 37523395

Gene position: 4031718-4031095 (Counterclockwise)

Preceding gene: 37523399

Following gene: 37523393

Centisome position: 86.54

GC content: 56.73

Gene sequence:

>624_bases
ATGACCAGAAGCGTAGAAACCACCGGAACTGCAAAAATCAGGGAAACCACGCGGTTGACCCTGATTCGTACGGGGCTGGG
CATTATCCGCGAAAAGGGTTTCAACAATTCCGGCCTTCAGGAGATTTTGCAGGCGAGCGGCGTGCCCAAGGGCTCGTTTT
ATCACTTTTTTGCCAGCAAAGAAGATTTTGGCCTGGCCATCATCGAATACGACGCGGGCGAGCACCAGCGGGAGATGGAG
CGCTTTTTAGGCGATACTTCCTGTGGTGCCGTCGAGCGGTTGCGCCGGTACTTTGAAGCCAAATGCCGCTATTTCGAGTC
GCGCCGGCACCGCGAGGGTTGTCTGCTCGGCAATCTCGGCCAGGAGCTTGCCGATCAAAACGAGACCTTTCGGGTGCGCA
TCGAGCGGTTTTTTGCCGATTGGTGCGCGGCTCTGGCCGGTTGCCTCAAAGAGGCCCAGAAGGCGCGCGAGATCCCGGCG
CACCTGAGCCCCGACAGCCTTGCGGCCTTTCTGGTCAATAGCTGGGAAGGGGCAATCACCCAGATGAAGATCACCAAGAG
CACCGAACCGCTGCAGTTATTTATGGATTTTGTCTTCGGAATGCTCCTTAAACCCTCTTCCTGA

Upstream 100 bases:

>100_bases
TTTGGGCGGGGGAGTGTGCTTGCGACCCTTGCAAAAATGAGACGACCAGTCTAATTTAGAGGGAGATTAGCGATTGATGG
AGCAGCCCTACCTGCAGCCC

Downstream 100 bases:

>100_bases
GTGCACCAGGGAGCGCAGGCCAACGGCATTAGACCAGCCGGTGCACAAGGATGCTCTCGAAGTGAAAACCTTCAGCGTCG
TCCGGAGCCGTTTTTTCGAG

Product: TetR family transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MTRSVETTGTAKIRETTRLTLIRTGLGIIREKGFNNSGLQEILQASGVPKGSFYHFFASKEDFGLAIIEYDAGEHQREME
RFLGDTSCGAVERLRRYFEAKCRYFESRRHREGCLLGNLGQELADQNETFRVRIERFFADWCAALAGCLKEAQKAREIPA
HLSPDSLAAFLVNSWEGAITQMKITKSTEPLQLFMDFVFGMLLKPSS

Sequences:

>Translated_207_residues
MTRSVETTGTAKIRETTRLTLIRTGLGIIREKGFNNSGLQEILQASGVPKGSFYHFFASKEDFGLAIIEYDAGEHQREME
RFLGDTSCGAVERLRRYFEAKCRYFESRRHREGCLLGNLGQELADQNETFRVRIERFFADWCAALAGCLKEAQKAREIPA
HLSPDSLAAFLVNSWEGAITQMKITKSTEPLQLFMDFVFGMLLKPSS
>Mature_206_residues
TRSVETTGTAKIRETTRLTLIRTGLGIIREKGFNNSGLQEILQASGVPKGSFYHFFASKEDFGLAIIEYDAGEHQREMER
FLGDTSCGAVERLRRYFEAKCRYFESRRHREGCLLGNLGQELADQNETFRVRIERFFADWCAALAGCLKEAQKAREIPAH
LSPDSLAAFLVNSWEGAITQMKITKSTEPLQLFMDFVFGMLLKPSS

Specific function: Transcriptional repressor for the dhaA haloalkane dehalogenase gene [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693141, Length=190, Percent_Identity=30, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 23445; Mature: 23314

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSVETTGTAKIRETTRLTLIRTGLGIIREKGFNNSGLQEILQASGVPKGSFYHFFASK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEECCC
EDFGLAIIEYDAGEHQREMERFLGDTSCGAVERLRRYFEAKCRYFESRRHREGCLLGNLG
CCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QELADQNETFRVRIERFFADWCAALAGCLKEAQKAREIPAHLSPDSLAAFLVNSWEGAIT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHE
QMKITKSTEPLQLFMDFVFGMLLKPSS
EEEECCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TRSVETTGTAKIRETTRLTLIRTGLGIIREKGFNNSGLQEILQASGVPKGSFYHFFASK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEECCC
EDFGLAIIEYDAGEHQREMERFLGDTSCGAVERLRRYFEAKCRYFESRRHREGCLLGNLG
CCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
QELADQNETFRVRIERFFADWCAALAGCLKEAQKAREIPAHLSPDSLAAFLVNSWEGAIT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCHHE
QMKITKSTEPLQLFMDFVFGMLLKPSS
EEEECCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10735862 [H]