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The map label for this gene is ycgM [C]

Identifier: 37523393

GI number: 37523393

Start: 4028508

End: 4029296

Strand: Reverse

Name: ycgM [C]

Synonym: gll3824

Alternate gene names: 37523393

Gene position: 4029296-4028508 (Counterclockwise)

Preceding gene: 37523395

Following gene: 37523392

Centisome position: 86.48

GC content: 66.16

Gene sequence:

>789_bases
ATGCACACCGTGCGTTTTTGCCACCCGCAGCTTCCCGACCACGCTCCTCACTACGGCCTGTTACACCCTGCCGGGACTAT
CGAGCGGCTCGACGGTGCCCCCTGGCTGGGGGGACAACCCACCGGCATCTGGTTCGATGTCGAGCAAGGACAACTGCTCG
CCCCCTGCCTGCCGGGCAAAATTGTCTGCGTCGGCAAAAACTACCGCGATCACGCCGCCGAGATGGCCCAGTTGCGCGGC
GACGCCGGGGTGCCTCCTGAACCGCTGCTCTTTCTCAAACCCCCCTCGGCCCTCGCGGCTCCCGGCGAATCCATCGTCTA
TCCGCCCCAGTCGGAGCGCGTCGATTACGAGGGCGAACTGGCTCTGGTCATCGGCCGCACCTGCCGCCGGGTGCCGGTGG
AGCGGGCTCTGGATTATCTATTCGGCTACACCGCCGCCAACGACGTCACCGCCCGCGACCTGCAGGGCAAGGACAAGCAG
TGGACCCGCGCCAAGGGTTTCGACAGCTTCTGTCCTTTGGGGCCTCTCATCGCCACAGAACTTGCTCCCGACGCCCACCT
GAGCACCACCCTCAACGGCAAGACCGTCCAGTCGAGCAGCATCGACCGGATGGTCTTCCCGCCTGCGGTTTTGATCTCCT
ACATCAGCGCGGTGATGACCCTGCAGCCGGGGGATGTGATCCTCACCGGCACCCCGGCGGGGATCGGTCCCATGCAGCCC
GGCGACGAGGTGGGCGTCACCATAGACGGCGTCGGCACCCTCACCAACCCGGTCGTCCGTGGGCTGTGA

Upstream 100 bases:

>100_bases
TGGGTGCGCTCCTTCAAGATGCCATACCGGCCGTGAGCCGCGTTTCCGCCGGTGGTTGGGGTGTGATTGAATGCAAGACA
TAGAAATTCTCAGCCGCCCG

Downstream 100 bases:

>100_bases
AGCAAAAACAAAACCAAAGACCCAAGCGGCCGGTTGCCCGCGGACGTTATCCTGTTTGAAAAAGCCGAAGTTATCGAACC
CATCATGGTCAAGCTCGTCA

Product: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MHTVRFCHPQLPDHAPHYGLLHPAGTIERLDGAPWLGGQPTGIWFDVEQGQLLAPCLPGKIVCVGKNYRDHAAEMAQLRG
DAGVPPEPLLFLKPPSALAAPGESIVYPPQSERVDYEGELALVIGRTCRRVPVERALDYLFGYTAANDVTARDLQGKDKQ
WTRAKGFDSFCPLGPLIATELAPDAHLSTTLNGKTVQSSSIDRMVFPPAVLISYISAVMTLQPGDVILTGTPAGIGPMQP
GDEVGVTIDGVGTLTNPVVRGL

Sequences:

>Translated_262_residues
MHTVRFCHPQLPDHAPHYGLLHPAGTIERLDGAPWLGGQPTGIWFDVEQGQLLAPCLPGKIVCVGKNYRDHAAEMAQLRG
DAGVPPEPLLFLKPPSALAAPGESIVYPPQSERVDYEGELALVIGRTCRRVPVERALDYLFGYTAANDVTARDLQGKDKQ
WTRAKGFDSFCPLGPLIATELAPDAHLSTTLNGKTVQSSSIDRMVFPPAVLISYISAVMTLQPGDVILTGTPAGIGPMQP
GDEVGVTIDGVGTLTNPVVRGL
>Mature_262_residues
MHTVRFCHPQLPDHAPHYGLLHPAGTIERLDGAPWLGGQPTGIWFDVEQGQLLAPCLPGKIVCVGKNYRDHAAEMAQLRG
DAGVPPEPLLFLKPPSALAAPGESIVYPPQSERVDYEGELALVIGRTCRRVPVERALDYLFGYTAANDVTARDLQGKDKQ
WTRAKGFDSFCPLGPLIATELAPDAHLSTTLNGKTVQSSSIDRMVFPPAVLISYISAVMTLQPGDVILTGTPAGIGPMQP
GDEVGVTIDGVGTLTNPVVRGL

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=222, Percent_Identity=42.3423423423423, Blast_Score=167, Evalue=9e-42,
Organism=Homo sapiens, GI40786394, Length=222, Percent_Identity=42.3423423423423, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI13654274, Length=208, Percent_Identity=40.8653846153846, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI215422413, Length=209, Percent_Identity=41.6267942583732, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI66348062, Length=199, Percent_Identity=41.7085427135678, Blast_Score=157, Evalue=1e-38,
Organism=Escherichia coli, GI1787428, Length=199, Percent_Identity=42.713567839196, Blast_Score=148, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17557057, Length=200, Percent_Identity=40.5, Blast_Score=148, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6324161, Length=224, Percent_Identity=30.8035714285714, Blast_Score=117, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28572127, Length=215, Percent_Identity=39.5348837209302, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28571789, Length=203, Percent_Identity=37.9310344827586, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24663695, Length=218, Percent_Identity=33.4862385321101, Blast_Score=116, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 27988; Mature: 27988

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTVRFCHPQLPDHAPHYGLLHPAGTIERLDGAPWLGGQPTGIWFDVEQGQLLAPCLPGK
CCCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEECCCCCEEECCCCCE
IVCVGKNYRDHAAEMAQLRGDAGVPPEPLLFLKPPSALAAPGESIVYPPQSERVDYEGEL
EEEECCCCHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHCCCCCEEECCCCCCCCCCCCE
ALVIGRTCRRVPVERALDYLFGYTAANDVTARDLQGKDKQWTRAKGFDSFCPLGPLIATE
EEEECCHHHCCCHHHHHHHHHCCCCCCCCCHHCCCCCCCCHHHHCCCCCCCCCCHHHHHH
LAPDAHLSTTLNGKTVQSSSIDRMVFPPAVLISYISAVMTLQPGDVILTGTPAGIGPMQP
CCCCCCEEEECCCCEEECCCCCCEECCHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCC
GDEVGVTIDGVGTLTNPVVRGL
CCCCCEEEECCCCHHHHHHHCC
>Mature Secondary Structure
MHTVRFCHPQLPDHAPHYGLLHPAGTIERLDGAPWLGGQPTGIWFDVEQGQLLAPCLPGK
CCCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCEEEEECCCCCEEECCCCCE
IVCVGKNYRDHAAEMAQLRGDAGVPPEPLLFLKPPSALAAPGESIVYPPQSERVDYEGEL
EEEECCCCHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHCCCCCEEECCCCCCCCCCCCE
ALVIGRTCRRVPVERALDYLFGYTAANDVTARDLQGKDKQWTRAKGFDSFCPLGPLIATE
EEEECCHHHCCCHHHHHHHHHCCCCCCCCCHHCCCCCCCCHHHHCCCCCCCCCCHHHHHH
LAPDAHLSTTLNGKTVQSSSIDRMVFPPAVLISYISAVMTLQPGDVILTGTPAGIGPMQP
CCCCCCEEEECCCCEEECCCCCCEECCHHHHHHHHHHHHEECCCCEEEECCCCCCCCCCC
GDEVGVTIDGVGTLTNPVVRGL
CCCCCEEEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]