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The map label for this gene is yajL [H]

Identifier: 37523322

GI number: 37523322

Start: 3963099

End: 3963647

Strand: Reverse

Name: yajL [H]

Synonym: gll3753

Alternate gene names: 37523322

Gene position: 3963647-3963099 (Counterclockwise)

Preceding gene: 37523323

Following gene: 37523321

Centisome position: 85.07

GC content: 66.67

Gene sequence:

>549_bases
ATGATCAAGGTGCTCGTGCCTTTGGCGGAGGGCTTCGAAGAAATCGAAGCGGTGACGATTATCGACGTGCTCAGGCGCGC
GGACATCGAGGTGACGGTGGCCGCCCTGGCGGACCTCGCGGTGCAGGGTTCCCACGGGATCACCTTGGTGGCTGATACGC
GACTGGATGAGATCAATCCCCTTACCTTTGACGCAGTGGTGCTGCCGGGCGGACCGGGGGTGGCCAGGCTGCGCGCCGAC
GAGCGCGTCCGCAAATTGCTTTTGGAGATGCGCGCCGCCGAGCGGTGGACCGCGGCCATCTGTGCCGCCCCGACGGTGCT
CTCGGACGCAGGTCTGCTCGCCGGGGCGCGTGCTACCAGTTACCCCTCGGTACGCCCCGAACTGACCGTCGGCGAGTACC
TGGAGACCAGCGTGGTCGTAGACGGGCGGATCGTCACCAGCCGGGGTGTCGGAACCGCGCTCGATTTTGCGCTGAAGCTG
GTGGCGCTTTGGGAGGGCGAATCCAAAGCCCAAGCGCTGGCGCGGGCCATGGTGGTCGGCAGCCCCTAA

Upstream 100 bases:

>100_bases
GGCGCGACCCGGGCGGTGGCGTGCGGTTGGTGGCCTATATCGCCGGTGCTTTTGAAGGCAGCGGGCGCTAGGATCGAGCC
GCAGCGCTTGGGAGACCCTG

Downstream 100 bases:

>100_bases
ATTCCCGAACGGCCGAGGGTCGCATACATTAGGTAAGAACCATCGGGATCGCTCCGCGTGCTTTACCGTCGCTTCGGCAA
AACCGATCTGCGCCTGTCGG

Product: 4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MIKVLVPLAEGFEEIEAVTIIDVLRRADIEVTVAALADLAVQGSHGITLVADTRLDEINPLTFDAVVLPGGPGVARLRAD
ERVRKLLLEMRAAERWTAAICAAPTVLSDAGLLAGARATSYPSVRPELTVGEYLETSVVVDGRIVTSRGVGTALDFALKL
VALWEGESKAQALARAMVVGSP

Sequences:

>Translated_182_residues
MIKVLVPLAEGFEEIEAVTIIDVLRRADIEVTVAALADLAVQGSHGITLVADTRLDEINPLTFDAVVLPGGPGVARLRAD
ERVRKLLLEMRAAERWTAAICAAPTVLSDAGLLAGARATSYPSVRPELTVGEYLETSVVVDGRIVTSRGVGTALDFALKL
VALWEGESKAQALARAMVVGSP
>Mature_182_residues
MIKVLVPLAEGFEEIEAVTIIDVLRRADIEVTVAALADLAVQGSHGITLVADTRLDEINPLTFDAVVLPGGPGVARLRAD
ERVRKLLLEMRAAERWTAAICAAPTVLSDAGLLAGARATSYPSVRPELTVGEYLETSVVVDGRIVTSRGVGTALDFALKL
VALWEGESKAQALARAMVVGSP

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=171, Percent_Identity=39.1812865497076, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI31543380, Length=171, Percent_Identity=39.1812865497076, Blast_Score=98, Evalue=4e-21,
Organism=Escherichia coli, GI87081736, Length=182, Percent_Identity=39.010989010989, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87082219, Length=154, Percent_Identity=31.8181818181818, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531319, Length=176, Percent_Identity=43.1818181818182, Blast_Score=109, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17558714, Length=178, Percent_Identity=35.9550561797753, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571932, Length=180, Percent_Identity=43.8888888888889, Blast_Score=123, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24653499, Length=179, Percent_Identity=41.8994413407821, Blast_Score=107, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 19197; Mature: 19197

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVLVPLAEGFEEIEAVTIIDVLRRADIEVTVAALADLAVQGSHGITLVADTRLDEINP
CEEEEEEHHCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHEECCCCEEEEECCCCCCCCC
LTFDAVVLPGGPGVARLRADERVRKLLLEMRAAERWTAAICAAPTVLSDAGLLAGARATS
EEEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHCCCCCCC
YPSVRPELTVGEYLETSVVVDGRIVTSRGVGTALDFALKLVALWEGESKAQALARAMVVG
CCCCCCCCCHHHHHHEEEEECCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
SP
CC
>Mature Secondary Structure
MIKVLVPLAEGFEEIEAVTIIDVLRRADIEVTVAALADLAVQGSHGITLVADTRLDEINP
CEEEEEEHHCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHEECCCCEEEEECCCCCCCCC
LTFDAVVLPGGPGVARLRADERVRKLLLEMRAAERWTAAICAAPTVLSDAGLLAGARATS
EEEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHCCCCCCC
YPSVRPELTVGEYLETSVVVDGRIVTSRGVGTALDFALKLVALWEGESKAQALARAMVVG
CCCCCCCCCHHHHHHEEEEECCEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
SP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]