Click here to switch to the map view.

The map label for this gene is rfbC [H]

Identifier: 37523271

GI number: 37523271

Start: 3909640

End: 3910200

Strand: Reverse

Name: rfbC [H]

Synonym: gvip503

Alternate gene names: 37523271

Gene position: 3910200-3909640 (Counterclockwise)

Preceding gene: 37523272

Following gene: 37523269

Centisome position: 83.93

GC content: 59.71

Gene sequence:

>561_bases
GTGCAACGCATCGAAACCGCGCTTCCGGGCGTCTATGTGATCGAACCGAAGGTCTTCGGCGACGCCCGCGGCTATTTTTA
TGAGTCCTACCACCGGGCCAAATTCGCCGAATTGGGAATCCCGGATGAGTTCGTGCAGGACAATTGCTCGCGTTCGGCGC
GGGGCGTCCTGCGCGGTCTCCACTACCAGTTGCGTTTCCCCCAGGCCAAACTCTGCCGGGTCGTGGAGGGCGAAGTCTTC
GATGTGGCCGTTGACATTCGCAAAGGCTCTCCAACCTTCGGCCAGTGGGCGGGCGTGGTCCTCTCCGCCGAAAATAGGCA
CCAGATCTACGTTCCGGCCGGTTTTGCCCACGGCTTCGCGGTGCTCTCGGAATCGGCGGAATTTCTTTACAAATGCAGCG
ATTTCTATCATCCCGAGGATGAGCAGGGAGTGCTCTGGAACGATCCGGACATCGGCATTCCCTGGCCGGTGGAGGCCCCT
GTTCTCTCGGGTAAGGACCAGAAATACTTGCCGCTCAACCAGACGGACCCGGAGCGGCTGCCGGTGTATCACCAGAAATA
A

Upstream 100 bases:

>100_bases
TGCGAAGTGGGCGCTGCGCCCGACCCCGATCCTCCCTTGCCGCCAAATTACGGTATATCTGGTAAGGCTCCAGCTGTAAA
TGCACACAGGGGAAAGTCGG

Downstream 100 bases:

>100_bases
TGGGCACGGGGGCACACCGAAGGGTGCCCCCCGCTTTTACACGTCGAAGGTTTCTTTGCCGGTGAACTTGACATCGACCG
GGTTAGGATTGTCGCCAATT

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MQRIETALPGVYVIEPKVFGDARGYFYESYHRAKFAELGIPDEFVQDNCSRSARGVLRGLHYQLRFPQAKLCRVVEGEVF
DVAVDIRKGSPTFGQWAGVVLSAENRHQIYVPAGFAHGFAVLSESAEFLYKCSDFYHPEDEQGVLWNDPDIGIPWPVEAP
VLSGKDQKYLPLNQTDPERLPVYHQK

Sequences:

>Translated_186_residues
MQRIETALPGVYVIEPKVFGDARGYFYESYHRAKFAELGIPDEFVQDNCSRSARGVLRGLHYQLRFPQAKLCRVVEGEVF
DVAVDIRKGSPTFGQWAGVVLSAENRHQIYVPAGFAHGFAVLSESAEFLYKCSDFYHPEDEQGVLWNDPDIGIPWPVEAP
VLSGKDQKYLPLNQTDPERLPVYHQK
>Mature_186_residues
MQRIETALPGVYVIEPKVFGDARGYFYESYHRAKFAELGIPDEFVQDNCSRSARGVLRGLHYQLRFPQAKLCRVVEGEVF
DVAVDIRKGSPTFGQWAGVVLSAENRHQIYVPAGFAHGFAVLSESAEFLYKCSDFYHPEDEQGVLWNDPDIGIPWPVEAP
VLSGKDQKYLPLNQTDPERLPVYHQK

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=177, Percent_Identity=51.9774011299435, Blast_Score=191, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17550412, Length=153, Percent_Identity=53.5947712418301, Blast_Score=157, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21104; Mature: 21104

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRIETALPGVYVIEPKVFGDARGYFYESYHRAKFAELGIPDEFVQDNCSRSARGVLRGL
CCCCHHHCCCEEEECCEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHH
HYQLRFPQAKLCRVVEGEVFDVAVDIRKGSPTFGQWAGVVLSAENRHQIYVPAGFAHGFA
HEEEECCHHHHHHHHCCCEEEEEEEEECCCCCCCCCCEEEEECCCCEEEEEECCHHHHHH
VLSESAEFLYKCSDFYHPEDEQGVLWNDPDIGIPWPVEAPVLSGKDQKYLPLNQTDPERL
HHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCEECCCCCEECCCCCCCCCCC
PVYHQK
CCCCCC
>Mature Secondary Structure
MQRIETALPGVYVIEPKVFGDARGYFYESYHRAKFAELGIPDEFVQDNCSRSARGVLRGL
CCCCHHHCCCEEEECCEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHHHHHH
HYQLRFPQAKLCRVVEGEVFDVAVDIRKGSPTFGQWAGVVLSAENRHQIYVPAGFAHGFA
HEEEECCHHHHHHHHCCCEEEEEEEEECCCCCCCCCCEEEEECCCCEEEEEECCHHHHHH
VLSESAEFLYKCSDFYHPEDEQGVLWNDPDIGIPWPVEAPVLSGKDQKYLPLNQTDPERL
HHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCEECCCCCEECCCCCCCCCCC
PVYHQK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]