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The map label for this gene is cysR [H]

Identifier: 37523132

GI number: 37523132

Start: 3758241

End: 3759215

Strand: Direct

Name: cysR [H]

Synonym: glr3563

Alternate gene names: 37523132

Gene position: 3758241-3759215 (Clockwise)

Preceding gene: 37523131

Following gene: 37523133

Centisome position: 80.67

GC content: 63.79

Gene sequence:

>975_bases
ATGACTGACATTCTCGTGATCGAAGATGATGCCCTCGTCCGGGAGAGCGTCCTGGAAGTGCTCGAAGCCCAGGGCTTTCG
GGCCATCGGCGCCCAGAACGGACAGGTGGGCCTTCGCCTCGCCGAGGAGCACCTGCCGGACTTGATCCTCTGCGATATCC
TGATGCCCGGCCTCGACGGCTACGCGGTGCTGGCCGCGCTGTCGGACAATCCGCTCACCCAGGGGATTCCCTTTGTTTTT
CTGACGGCGAGGGTGGCGAAGCTGAATTGGCGGCAGGCGATGGCCATGGGTGCCGACGATTATCTGCCCAAGCCCTTTAC
TGCCGAGGAGTTGCTGGAGACTGTCGCCATCCGGCTCAAAAAGCACGCGCTGCTTCGCTCCCTCCCAGATACTTTCAACA
CAAAAAAACCGGCGGCCCCACCGCAGCATTCCATCTCCCATTTTGCTCCCAACCAGGGCATTCCCCTGCACCCGGACAGT
TTCTGGCAGGTACACCACGGCCTGGTGAAGCTCAGCGCCGCCCTCGTCGAGGGTGAGCCGGTGGTGGTGGGCTGGGCCGT
TGCGCCGATGCTCTTCGGGACCGATGCGGTCGAATCGGAGGTGTATTACCAGGCCTCAGCCGTGGGCCGGGTCGAACTTG
CAAAATTCTCGGCCCAGGAGGTGGCCGCATCGCCCCATATGGCCCAAGCCCTGCTCTCCCGCCTGTATCAGAGCAATGCC
TTGCTGGCTGTCTGTGGCCAACGGCGGGCCGATGACCGGCTGCGGGGGTTGTTGCTGCTGCTCAAACGGGAGGTGGGGGA
GCCCTGCAGGGGGGGCACGCGGCTGCGGGTCCGCTTCACCCACCAGGACCTGGCCAATACGATCGGAACGGCCCGCGCCA
CGGTCACCTTATTGCTGAACCGGTTCAAACAATGCGGCTGGATTGCCGTCGAGAGCGATCGCCGCCTGTGCATCTCGGAT
GCGCTCCCGCACTGA

Upstream 100 bases:

>100_bases
AGGAGGCTGGTCGAGCTGTTAAAGGGGCGGCTCGCCTTCGAAAGCCGTCCCCAGCAAGGAACCACGTTCACCGTTGCCCT
GCCCCTCGAGGAGCCGGCCG

Downstream 100 bases:

>100_bases
GCGGTGCGCCATGTTGCCCAGCAACCTCCTGAATTCTGCCGTCGCGTTAGTTGACGACAACCTGCCAATAACAACTTTTG
TATCATCTGGACAGGCTTCT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTDILVIEDDALVRESVLEVLEAQGFRAIGAQNGQVGLRLAEEHLPDLILCDILMPGLDGYAVLAALSDNPLTQGIPFVF
LTARVAKLNWRQAMAMGADDYLPKPFTAEELLETVAIRLKKHALLRSLPDTFNTKKPAAPPQHSISHFAPNQGIPLHPDS
FWQVHHGLVKLSAALVEGEPVVVGWAVAPMLFGTDAVESEVYYQASAVGRVELAKFSAQEVAASPHMAQALLSRLYQSNA
LLAVCGQRRADDRLRGLLLLLKREVGEPCRGGTRLRVRFTHQDLANTIGTARATVTLLLNRFKQCGWIAVESDRRLCISD
ALPH

Sequences:

>Translated_324_residues
MTDILVIEDDALVRESVLEVLEAQGFRAIGAQNGQVGLRLAEEHLPDLILCDILMPGLDGYAVLAALSDNPLTQGIPFVF
LTARVAKLNWRQAMAMGADDYLPKPFTAEELLETVAIRLKKHALLRSLPDTFNTKKPAAPPQHSISHFAPNQGIPLHPDS
FWQVHHGLVKLSAALVEGEPVVVGWAVAPMLFGTDAVESEVYYQASAVGRVELAKFSAQEVAASPHMAQALLSRLYQSNA
LLAVCGQRRADDRLRGLLLLLKREVGEPCRGGTRLRVRFTHQDLANTIGTARATVTLLLNRFKQCGWIAVESDRRLCISD
ALPH
>Mature_323_residues
TDILVIEDDALVRESVLEVLEAQGFRAIGAQNGQVGLRLAEEHLPDLILCDILMPGLDGYAVLAALSDNPLTQGIPFVFL
TARVAKLNWRQAMAMGADDYLPKPFTAEELLETVAIRLKKHALLRSLPDTFNTKKPAAPPQHSISHFAPNQGIPLHPDSF
WQVHHGLVKLSAALVEGEPVVVGWAVAPMLFGTDAVESEVYYQASAVGRVELAKFSAQEVAASPHMAQALLSRLYQSNAL
LAVCGQRRADDRLRGLLLLLKREVGEPCRGGTRLRVRFTHQDLANTIGTARATVTLLLNRFKQCGWIAVESDRRLCISDA
LPH

Specific function: Probably regulates the expression of genes from the sulfate permease complex [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=37.2881355932203, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082012, Length=153, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786911, Length=123, Percent_Identity=34.1463414634146, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789809, Length=143, Percent_Identity=30.0699300699301, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787375, Length=124, Percent_Identity=28.2258064516129, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786784, Length=120, Percent_Identity=34.1666666666667, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI2367329, Length=121, Percent_Identity=35.5371900826446, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790863, Length=108, Percent_Identity=29.6296296296296, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788394, Length=125, Percent_Identity=28, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 35470; Mature: 35339

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDILVIEDDALVRESVLEVLEAQGFRAIGAQNGQVGLRLAEEHLPDLILCDILMPGLDG
CCCEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCEEEEEHHHHCCHHEEHHHHHCCCCC
YAVLAALSDNPLTQGIPFVFLTARVAKLNWRQAMAMGADDYLPKPFTAEELLETVAIRLK
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
KHALLRSLPDTFNTKKPAAPPQHSISHFAPNQGIPLHPDSFWQVHHGLVKLSAALVEGEP
HHHHHHHCCHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
VVVGWAVAPMLFGTDAVESEVYYQASAVGRVELAKFSAQEVAASPHMAQALLSRLYQSNA
EEEHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
LLAVCGQRRADDRLRGLLLLLKREVGEPCRGGTRLRVRFTHQDLANTIGTARATVTLLLN
EEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
RFKQCGWIAVESDRRLCISDALPH
HHHHCCEEEECCCCCEECCCCCCC
>Mature Secondary Structure 
TDILVIEDDALVRESVLEVLEAQGFRAIGAQNGQVGLRLAEEHLPDLILCDILMPGLDG
CCEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCEEEEEHHHHCCHHEEHHHHHCCCCC
YAVLAALSDNPLTQGIPFVFLTARVAKLNWRQAMAMGADDYLPKPFTAEELLETVAIRLK
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
KHALLRSLPDTFNTKKPAAPPQHSISHFAPNQGIPLHPDSFWQVHHGLVKLSAALVEGEP
HHHHHHHCCHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
VVVGWAVAPMLFGTDAVESEVYYQASAVGRVELAKFSAQEVAASPHMAQALLSRLYQSNA
EEEHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
LLAVCGQRRADDRLRGLLLLLKREVGEPCRGGTRLRVRFTHQDLANTIGTARATVTLLLN
EEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
RFKQCGWIAVESDRRLCISDALPH
HHHHCCEEEECCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]