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The map label for this gene is uppP

Identifier: 37522850

GI number: 37522850

Start: 3487685

End: 3488557

Strand: Direct

Name: uppP

Synonym: glr3281

Alternate gene names: 37522850

Gene position: 3487685-3488557 (Clockwise)

Preceding gene: 37522849

Following gene: 37522855

Centisome position: 74.86

GC content: 61.86

Gene sequence:

>873_bases
ATGCAGCAGCAGATAGGCATCTTCGAGGCAATTGTGCTCGGGTTTGTGCAGGGGATCACCGAGTACTTTCCCATCAGCAG
CACCGCCCACCTGCGGGTCGTACCGGCCCTGCTGGGCTGGGCCGATCCGGGCACGGCCTATTCGGCGGTGATTCAGCTGG
GCAGTCTGCTCGCGGTGCTCACGTATTTCTACAAAGATCTCGTCGAGATCCTCTCCGGGACGGTACGGGCTCTGCGCACC
GGGGACACCCAATCGCGCGAGGTGCGCCTTTTCTGGGGAATTATTCTGGGCACGATCCCGATTGTGATCGCGGGACTCGC
CCTCAAATCCACCCTCGAAGCCCCCGGCTCGCCGCTGAGAGCGCTCAGTGTGATCGCCGTCGCCTCGATTGTGATGGCGG
CCTTGCTGTGGCTCTCGGAGAGTCTGGGCAAGCGGACGCGCACGATGAAGGGCATCCGGGTGATCGACGGCATCTTGATC
GGCTGTGCCCAGGCGTTGGCCCTGGTACCGGGGGTCTCCCGCTCCGGTTCGACACTCACGGCCGCATTGTTTCTGGGCTT
TCAGCGCGCGGACGGAGCGCGCTTCTCGTTTTTGCTCGCCATCCCGGCGATTTTTCTGAGTGGCCTGCTCGAACTGAAGG
TACTGGTCGATGAAGGTTTCAGCGGCGGTATCGGTCCAATTGTGGCGGGCTTTGTCTCTTCGACGGTCTTCAGCTATCTG
GCGATTGCCTGGCTGCTGAAGTTTTTGCAGACGCGCTCGACGCTCGTCTTTGTGATTTACCGGTTTTTCTTTGGCGCCCT
GCTGCTGGGGCTGCTCGCAGCCGGGTTGCTGCCGGACATCGAGCCGGTGCGCCAGGCGCTCAATCTTCCATGA

Upstream 100 bases:

>100_bases
CGGGCACAACGGCGATTAGGCCCGTGCGATCCCCGCGGCCACCGGTGACCTGGGCTGTACTTCCCTGCTAACCTGAGTCC
AGTTTCAAGCCGGAAAAGGC

Downstream 100 bases:

>100_bases
TCCGGGGCACCTTAAAAAAGTCCTCGGCCCGCTCCGGCGCATTTTCGAGGATACCTTCGCGGTCCTCGAACACCACCAGC
GCGTCCGGCCGCACGACGTT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MQQQIGIFEAIVLGFVQGITEYFPISSTAHLRVVPALLGWADPGTAYSAVIQLGSLLAVLTYFYKDLVEILSGTVRALRT
GDTQSREVRLFWGIILGTIPIVIAGLALKSTLEAPGSPLRALSVIAVASIVMAALLWLSESLGKRTRTMKGIRVIDGILI
GCAQALALVPGVSRSGSTLTAALFLGFQRADGARFSFLLAIPAIFLSGLLELKVLVDEGFSGGIGPIVAGFVSSTVFSYL
AIAWLLKFLQTRSTLVFVIYRFFFGALLLGLLAAGLLPDIEPVRQALNLP

Sequences:

>Translated_290_residues
MQQQIGIFEAIVLGFVQGITEYFPISSTAHLRVVPALLGWADPGTAYSAVIQLGSLLAVLTYFYKDLVEILSGTVRALRT
GDTQSREVRLFWGIILGTIPIVIAGLALKSTLEAPGSPLRALSVIAVASIVMAALLWLSESLGKRTRTMKGIRVIDGILI
GCAQALALVPGVSRSGSTLTAALFLGFQRADGARFSFLLAIPAIFLSGLLELKVLVDEGFSGGIGPIVAGFVSSTVFSYL
AIAWLLKFLQTRSTLVFVIYRFFFGALLLGLLAAGLLPDIEPVRQALNLP
>Mature_290_residues
MQQQIGIFEAIVLGFVQGITEYFPISSTAHLRVVPALLGWADPGTAYSAVIQLGSLLAVLTYFYKDLVEILSGTVRALRT
GDTQSREVRLFWGIILGTIPIVIAGLALKSTLEAPGSPLRALSVIAVASIVMAALLWLSESLGKRTRTMKGIRVIDGILI
GCAQALALVPGVSRSGSTLTAALFLGFQRADGARFSFLLAIPAIFLSGLLELKVLVDEGFSGGIGPIVAGFVSSTVFSYL
AIAWLLKFLQTRSTLVFVIYRFFFGALLLGLLAAGLLPDIEPVRQALNLP

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=272, Percent_Identity=32.3529411764706, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_GLOVI (Q7NG92)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_926227.1
- GeneID:   2601683
- GenomeReviews:   BA000045_GR
- KEGG:   gvi:glr3281
- NMPDR:   fig|251221.1.peg.3281
- HOGENOM:   HBG391969
- OMA:   YEASSIR
- ProtClustDB:   PRK00281
- BioCyc:   GVIO251221:GLR3281-MONOMER
- BRENDA:   3.6.1.27
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30881; Mature: 30881

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15b9de70)-; HASH(0x1075b4d8)-; HASH(0x135dd920)-; HASH(0x16d737b8)-; HASH(0x1038f7e4)-; HASH(0x16ea381c)-; HASH(0x147144b8)-; HASH(0x163c5794)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQQIGIFEAIVLGFVQGITEYFPISSTAHLRVVPALLGWADPGTAYSAVIQLGSLLAVL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
TYFYKDLVEILSGTVRALRTGDTQSREVRLFWGIILGTIPIVIAGLALKSTLEAPGSPLR
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ALSVIAVASIVMAALLWLSESLGKRTRTMKGIRVIDGILIGCAQALALVPGVSRSGSTLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
AALFLGFQRADGARFSFLLAIPAIFLSGLLELKVLVDEGFSGGIGPIVAGFVSSTVFSYL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AIAWLLKFLQTRSTLVFVIYRFFFGALLLGLLAAGLLPDIEPVRQALNLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCH
>Mature Secondary Structure
MQQQIGIFEAIVLGFVQGITEYFPISSTAHLRVVPALLGWADPGTAYSAVIQLGSLLAVL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
TYFYKDLVEILSGTVRALRTGDTQSREVRLFWGIILGTIPIVIAGLALKSTLEAPGSPLR
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ALSVIAVASIVMAALLWLSESLGKRTRTMKGIRVIDGILIGCAQALALVPGVSRSGSTLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
AALFLGFQRADGARFSFLLAIPAIFLSGLLELKVLVDEGFSGGIGPIVAGFVSSTVFSYL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AIAWLLKFLQTRSTLVFVIYRFFFGALLLGLLAAGLLPDIEPVRQALNLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14621292