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The map label for this gene is lacG [H]

Identifier: 37522799

GI number: 37522799

Start: 3435813

End: 3437357

Strand: Direct

Name: lacG [H]

Synonym: glr3230

Alternate gene names: 37522799

Gene position: 3435813-3437357 (Clockwise)

Preceding gene: 37522798

Following gene: 37522801

Centisome position: 73.75

GC content: 64.4

Gene sequence:

>1545_bases
ATGCCCGAGTCACACACCGACAACACCGAGCCAAAAGGGAGCGGCGATTTTCTCTGGGGGGTGGCCTCCTCCGGCTACCA
GAGCGAGGGCGGCTTCAACGCTCCCGGCCAGCCCCACAACAACTGGGCGCGCGGCGAAGCGAGAGGTGCCGTGATGCGCA
CAGGGGCCGCAGCCCAGTTCTGGACGCGCTACGAAGCCGATTTTTTGCTCTGCCGGGGCATGGGCCTCAATGCCTTTCGC
CTGGGACTGGAGTGGGCGCGCATCCAACCGCGCTTCGAGGCGCGGCCCGGCCCCGCTCCCGCCTTTGATACCGCCGCCCT
CGACGCTTACGCCGAGCGGCTTGCTGCCTGCCGCCGCGCGGGTCTGGAGCCGGTTATGACGCTGCACCACTTTACCCATC
CCGCCTGGTTGGGGGCGGACGCGTGGCTTGCCCCCGCCACCGTCGAAGGTTTTGCCGAGTATGTCCGCGTCGCCGTGGGC
CATATCAACCGCCGCCTGATCGATTGCTATGGTCTGGCGCCGGTGCACTGGTACATCACCATCAATGAGCCGAACATGCT
GGTGATCAACAGCTACTTCGGCCGTCAGTTTCCGGCCGGGTCGCACCGGGGGACGGAGGCGAGCCTGCGGGCCTACGACC
ACCTGCTTGCCGCCCACATCCGGGCTTACAACACCATTCACAATCTCTACGAGCAAGCGGGTTGGCCCCGACCGCGCGTC
ACCCTCAACACCTTCGCAAGCGATCTCTACTGGTCCGACAAGGTGCTCTGGGACCTGTTGTGCCTGCGCGAGCGGGCCAT
TCCCGCCGCCAATCTGCGCGAGCACCTGCATCGGCAGGCGGAGCGCTTCGAGGCGGCGCTGGCGGCGGCGAAATTGCCCT
TTGTGCGGGATCTGCCCTACCGCACCGGCCGGCTTGTGCACTGGTGGGCCAACCGCTTCGGGTACCGTTCCTTCGATGCT
CGCCACTTTGCGCTGTTGTTGCGCACGCTGGAGGCGAGTCCGCGGGCACGGGTCATCGATTATGTCGCCATCGACTATTA
CGACCCGTTCGTGGCCCATACGCTGCGCCTGCCCTCGTTTTCGGATTTTGAATTTAAGACGACGGGTCTGCGCGCCTGGA
TGATGAGCGGCATTACCAGCAAATGGTGGGACTGGCGCAGTCTGCCGGAGGGATTGCATTTTTTTTGCAGTCACTACGCG
GCGGAGTACGCTCTGCCGGTGCTCATCGCCGAAAACGGCATGGCTTTGCGGCGCAAACCCGACAACAGCGCTGCCGGTCA
CCGCCCGGATCAGCTGTTAAGAAGCCAGTTTCTCGAAGCGCATGTCCAGCAGGTGCAGCGGTTGTGCGCCGAGGGGGTGC
CGGTGGCCGGCTATCTGCACTGGTCGCTTACCGACAATTACGAATGGGGCTCCTACACGCCGCGCTTTGGCCTGTTTGCT
ATTGACTTTGCCAGGGGCAGTGAGCGGCTGGTTGAAGATCACCTGGGGGATAGGCCCTCCGAGACCTACGCCCGCCTGGT
GCGTGCCATGATGCCTGGCACCTGA

Upstream 100 bases:

>100_bases
AGCATCTGGCTTTTATGCGCTTCCAGGCGCGAAAATACGGGCGTCCCACCGCGGCCCTCGCCGTCGTCGAATCGATCCTT
GCCCGCCTGAGTGTCTAAAG

Downstream 100 bases:

>100_bases
TGTCTGGCGGTTGGCTTTGCACGAAAGTCTGTGGAGCGAGAGGCGGAACCCCCTTCGGGTTCCCCTCTCGCGCTCTCCAA
CCTCCCCGCGTCGAGGGGGT

Product: beta-glycosidase

Products: NA

Alternate protein names: Beta-D-phosphogalactoside galactohydrolase; PGALase; P-beta-Gal; PBG [H]

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MPESHTDNTEPKGSGDFLWGVASSGYQSEGGFNAPGQPHNNWARGEARGAVMRTGAAAQFWTRYEADFLLCRGMGLNAFR
LGLEWARIQPRFEARPGPAPAFDTAALDAYAERLAACRRAGLEPVMTLHHFTHPAWLGADAWLAPATVEGFAEYVRVAVG
HINRRLIDCYGLAPVHWYITINEPNMLVINSYFGRQFPAGSHRGTEASLRAYDHLLAAHIRAYNTIHNLYEQAGWPRPRV
TLNTFASDLYWSDKVLWDLLCLRERAIPAANLREHLHRQAERFEAALAAAKLPFVRDLPYRTGRLVHWWANRFGYRSFDA
RHFALLLRTLEASPRARVIDYVAIDYYDPFVAHTLRLPSFSDFEFKTTGLRAWMMSGITSKWWDWRSLPEGLHFFCSHYA
AEYALPVLIAENGMALRRKPDNSAAGHRPDQLLRSQFLEAHVQQVQRLCAEGVPVAGYLHWSLTDNYEWGSYTPRFGLFA
IDFARGSERLVEDHLGDRPSETYARLVRAMMPGT

Sequences:

>Translated_514_residues
MPESHTDNTEPKGSGDFLWGVASSGYQSEGGFNAPGQPHNNWARGEARGAVMRTGAAAQFWTRYEADFLLCRGMGLNAFR
LGLEWARIQPRFEARPGPAPAFDTAALDAYAERLAACRRAGLEPVMTLHHFTHPAWLGADAWLAPATVEGFAEYVRVAVG
HINRRLIDCYGLAPVHWYITINEPNMLVINSYFGRQFPAGSHRGTEASLRAYDHLLAAHIRAYNTIHNLYEQAGWPRPRV
TLNTFASDLYWSDKVLWDLLCLRERAIPAANLREHLHRQAERFEAALAAAKLPFVRDLPYRTGRLVHWWANRFGYRSFDA
RHFALLLRTLEASPRARVIDYVAIDYYDPFVAHTLRLPSFSDFEFKTTGLRAWMMSGITSKWWDWRSLPEGLHFFCSHYA
AEYALPVLIAENGMALRRKPDNSAAGHRPDQLLRSQFLEAHVQQVQRLCAEGVPVAGYLHWSLTDNYEWGSYTPRFGLFA
IDFARGSERLVEDHLGDRPSETYARLVRAMMPGT
>Mature_513_residues
PESHTDNTEPKGSGDFLWGVASSGYQSEGGFNAPGQPHNNWARGEARGAVMRTGAAAQFWTRYEADFLLCRGMGLNAFRL
GLEWARIQPRFEARPGPAPAFDTAALDAYAERLAACRRAGLEPVMTLHHFTHPAWLGADAWLAPATVEGFAEYVRVAVGH
INRRLIDCYGLAPVHWYITINEPNMLVINSYFGRQFPAGSHRGTEASLRAYDHLLAAHIRAYNTIHNLYEQAGWPRPRVT
LNTFASDLYWSDKVLWDLLCLRERAIPAANLREHLHRQAERFEAALAAAKLPFVRDLPYRTGRLVHWWANRFGYRSFDAR
HFALLLRTLEASPRARVIDYVAIDYYDPFVAHTLRLPSFSDFEFKTTGLRAWMMSGITSKWWDWRSLPEGLHFFCSHYAA
EYALPVLIAENGMALRRKPDNSAAGHRPDQLLRSQFLEAHVQQVQRLCAEGVPVAGYLHWSLTDNYEWGSYTPRFGLFAI
DFARGSERLVEDHLGDRPSETYARLVRAMMPGT

Specific function: Can Hydrolyze Salicin And Arbutin. [C]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI13273313, Length=507, Percent_Identity=26.0355029585799, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI32481206, Length=485, Percent_Identity=24.9484536082474, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI110681710, Length=494, Percent_Identity=22.0647773279352, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI2367270, Length=483, Percent_Identity=23.6024844720497, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789070, Length=500, Percent_Identity=23.2, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356577, Length=485, Percent_Identity=22.8865979381443, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR005928 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.85 [H]

Molecular weight: Translated: 58423; Mature: 58291

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESHTDNTEPKGSGDFLWGVASSGYQSEGGFNAPGQPHNNWARGEARGAVMRTGAAAQF
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHH
WTRYEADFLLCRGMGLNAFRLGLEWARIQPRFEARPGPAPAFDTAALDAYAERLAACRRA
HHHHCCCEEEEECCCCCHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GLEPVMTLHHFTHPAWLGADAWLAPATVEGFAEYVRVAVGHINRRLIDCYGLAPVHWYIT
CCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
INEPNMLVINSYFGRQFPAGSHRGTEASLRAYDHLLAAHIRAYNTIHNLYEQAGWPRPRV
ECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
TLNTFASDLYWSDKVLWDLLCLRERAIPAANLREHLHRQAERFEAALAAAKLPFVRDLPY
EHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCC
RTGRLVHWWANRFGYRSFDARHFALLLRTLEASPRARVIDYVAIDYYDPFVAHTLRLPSF
CCCCEEEEHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHCCCCCC
SDFEFKTTGLRAWMMSGITSKWWDWRSLPEGLHFFCSHYAAEYALPVLIAENGMALRRKP
CCCCEEHHHHHHHHHHCCCHHCCCHHCCHHHHHHHHHHHHHHHCEEEEEECCCCEEEECC
DNSAAGHRPDQLLRSQFLEAHVQQVQRLCAEGVPVAGYLHWSLTDNYEWGSYTPRFGLFA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCEEE
IDFARGSERLVEDHLGDRPSETYARLVRAMMPGT
EEECCCHHHHHHHHCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PESHTDNTEPKGSGDFLWGVASSGYQSEGGFNAPGQPHNNWARGEARGAVMRTGAAAQF
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHH
WTRYEADFLLCRGMGLNAFRLGLEWARIQPRFEARPGPAPAFDTAALDAYAERLAACRRA
HHHHCCCEEEEECCCCCHHHHCCHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GLEPVMTLHHFTHPAWLGADAWLAPATVEGFAEYVRVAVGHINRRLIDCYGLAPVHWYIT
CCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
INEPNMLVINSYFGRQFPAGSHRGTEASLRAYDHLLAAHIRAYNTIHNLYEQAGWPRPRV
ECCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
TLNTFASDLYWSDKVLWDLLCLRERAIPAANLREHLHRQAERFEAALAAAKLPFVRDLPY
EHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCC
RTGRLVHWWANRFGYRSFDARHFALLLRTLEASPRARVIDYVAIDYYDPFVAHTLRLPSF
CCCCEEEEHHHHCCCCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHCCCCCC
SDFEFKTTGLRAWMMSGITSKWWDWRSLPEGLHFFCSHYAAEYALPVLIAENGMALRRKP
CCCCEEHHHHHHHHHHCCCHHCCCHHCCHHHHHHHHHHHHHHHCEEEEEECCCCEEEECC
DNSAAGHRPDQLLRSQFLEAHVQQVQRLCAEGVPVAGYLHWSLTDNYEWGSYTPRFGLFA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCEEE
IDFARGSERLVEDHLGDRPSETYARLVRAMMPGT
EEECCCHHHHHHHHCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA