Click here to switch to the map view.

The map label for this gene is cirA [H]

Identifier: 37522672

GI number: 37522672

Start: 3305741

End: 3308062

Strand: Reverse

Name: cirA [H]

Synonym: gll3103

Alternate gene names: 37522672

Gene position: 3308062-3305741 (Counterclockwise)

Preceding gene: 37522676

Following gene: 37522671

Centisome position: 71.0

GC content: 61.37

Gene sequence:

>2322_bases
ATGGAGGCTCCCCTGGACAACGGTTGCTGTGATTTGCTTGCAATCTACTCAAGAACGAGAATCGTTGTCAAAGAACCGGA
TAGTTTTGGCGGGTGCGGCCAGCTTTTCAGAAACGTCCTGCTGTGCAAAAGCCACAGGCCCAACAAGACTAAGCCTCTGC
GCGCAAAAAGTCTGTCCCCCGGGGGGGTATATCCCCAAAGTAGGGGGAAGGGGCACAATCTCCGTGGGCACATTAGAAAA
GTTTTAATTTCTATGTCGGTACGCATTCGAACAAAGATTGGTACATATGCATTGTTTGTGCTGGCGGGCTTTCAGCTTGT
CGGCGGGCTTGCGTCCGCCCAGATCATTCCTACCCGCGACAGCCTTGCCAAACCTTCCCAGGCAGCCCGCGATCTGCTTG
CTGCTCCGACTGTAGGGCCAATCGCCCAGGTGCCTTCGACTCCCCAACCGGACGCCGCCGATCCGGACGGGGCAACCACT
CTGGATGAAACCCTGGTGGAGGGAAGGCTCGCCCCCAGGCGATCGACGCCGGTGTTCACGATCACCAGAGAGGACATTCA
AAAGAAGGCGGCGGTGAATCTGGCGGACGCGCTGCGGGGGGTACCGGGTTTTGCCATTAACGACGCCGGGCGCGGTGCGG
ATTTTCACAACGGCTCGTACTACCGGGGGGCGACGGTCAACCAGTCGGCGCTGCTCATCAACGGCCGCCAGATCAAAACC
GGCCTCAACTCCAACCACGGCGCCACCGACTACAACAGCATCCCGGTGGAAGGGATCAAGCGCATCGAGCTGCTCGGTCC
CGGTGCCGGCACAACCCTCTACGGTTCGGATGTGATCGGCGGCGTCATCAACATCATCACCGAGGAGGGACCGGCAGTCC
CGACGTTTTCCGGCAGCGCCGAGTACGGCTCCTACGGCGAATCGATCTACCGCACCTCCTACGGCGGTACCAGCGAACGG
CTCAAATACAACTTCGGCTATCAGAGCTACGGGGCCACCAACAACTTTCCGGTGCCGGTGGGTTCCACCAACCGGGGAGA
GGATGGGCGGCTGATGAACGCCGACATGTACACCGCGAGCTACCAGGGCAGTGCCACCTATACCTTTGATCGGCGCAACA
ACCTGACGTTTGATTTATTCAAGAACCTGAGCCGCAAGGGCCTGATTATCGGCAACTCCAAAGACCGGCTCGATCGCGAC
GGTCTCAATGTCGGCCTCACCTGGCGGACACTGCTTGGGGAGGGCAACGACTCGGTGCTGGTCACCACCCTGGGCTACGT
TGACGATTTTTTCAGCACCTACGGCCCGGTCCAGACCGACTACTTCAAGGCCGTGCAACTGGCCTCCAAGTTCTACCAGG
CCCGCATCGACCACACCTGGCGCACCAGCCCGGGCAACACGCTGCGCTGGGGGGTGGACACCAGGCACAACACGCTGCTC
AGCACCCAGAACAACACCAGCCCCGACCCGATCTTTTTTGGGCTGGGCGGCACCACCGACACGGCGATCACCAACACCGG
CATCTTCGCCCTCGATACCTGGCAGATCGTGGAAGGGTTGCAGCTGGATCTGGGCCTGCGCCAGACCTTTGACAGCAAGT
TCGGCAGCTACCTCAACCCGAGCGCCGGGTTGCGCTGGCAGATTATCCCGGAGGTAGCCCTGCGCGCCAGCTACGCTTCG
GTGCAGCGCAACCCCGGACCGGACTTTTTGTTCTTGCCCGACGCGGCGGAAGGATTTTTGCCCAATCCCGACTTGAAGCC
GGAGCGCGGCTCGGTCTACAACGCCGGTTTTGACCTGCGCTTCGCCGACAATCTCCGGGGCGAGGTCACCTACTTCGGCA
GCCTTATCCAGGATCGCATCGGCAACGGACCGCTGCCGGCCGACCCGACCCTCACCCAGCGCACCAACATCGGCGCGGTC
GGCACCAACGGCGTCGAGGCGGGGATCAAATGGCAGATCGATCCGCAGTGGTCGAGCTATCTGAGCTACACCTACACCAA
GATCAAAATCGAGGAGGGCCGCTCCCTGGGCCTGTTGCGTTTTTTGCCCGAGTCGGTGGGGCAGGTGGGCGTGGGCTACG
ACAACCAGGGCCTGCAGGTGAACGTGTTCGTCAACTACAACAGCGGTGCGGCGCGCACCAATGCGCTCACCTCCTACACC
ACCCCCTTCGCCACGATCGACCTGCGCGCCGCCATCCCGATCAACCGGGCTTTGGCGCTGACGGTCTACCTGGCCAACCT
GGCGGATGTGCAGTACGAGCGGGTCAACACGTTCTACTCGCCCGGTCTGACCTACCGCGTCGGACTGCAGACCAGCTTTT
AG

Upstream 100 bases:

>100_bases
GAGCAGACAGAAGACTTCGCCCGCCTCGATGCGCAGATTGAGTCCATCGAGGGACGGGACGGCCGTGCCGTAGTTCTTGG
TCAAGTCGACGGCTTCGAGC

Downstream 100 bases:

>100_bases
GTGTAATGCTTGAAAAGCACGAGGCGTGGAGCCGGAGCGGGTGGATACAGAATTGCCCATCGGTGGGGCCGGGGGAGATT
GGCCGCGCCAGAACGAGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 773; Mature: 773

Protein sequence:

>773_residues
MEAPLDNGCCDLLAIYSRTRIVVKEPDSFGGCGQLFRNVLLCKSHRPNKTKPLRAKSLSPGGVYPQSRGKGHNLRGHIRK
VLISMSVRIRTKIGTYALFVLAGFQLVGGLASAQIIPTRDSLAKPSQAARDLLAAPTVGPIAQVPSTPQPDAADPDGATT
LDETLVEGRLAPRRSTPVFTITREDIQKKAAVNLADALRGVPGFAINDAGRGADFHNGSYYRGATVNQSALLINGRQIKT
GLNSNHGATDYNSIPVEGIKRIELLGPGAGTTLYGSDVIGGVINIITEEGPAVPTFSGSAEYGSYGESIYRTSYGGTSER
LKYNFGYQSYGATNNFPVPVGSTNRGEDGRLMNADMYTASYQGSATYTFDRRNNLTFDLFKNLSRKGLIIGNSKDRLDRD
GLNVGLTWRTLLGEGNDSVLVTTLGYVDDFFSTYGPVQTDYFKAVQLASKFYQARIDHTWRTSPGNTLRWGVDTRHNTLL
STQNNTSPDPIFFGLGGTTDTAITNTGIFALDTWQIVEGLQLDLGLRQTFDSKFGSYLNPSAGLRWQIIPEVALRASYAS
VQRNPGPDFLFLPDAAEGFLPNPDLKPERGSVYNAGFDLRFADNLRGEVTYFGSLIQDRIGNGPLPADPTLTQRTNIGAV
GTNGVEAGIKWQIDPQWSSYLSYTYTKIKIEEGRSLGLLRFLPESVGQVGVGYDNQGLQVNVFVNYNSGAARTNALTSYT
TPFATIDLRAAIPINRALALTVYLANLADVQYERVNTFYSPGLTYRVGLQTSF

Sequences:

>Translated_773_residues
MEAPLDNGCCDLLAIYSRTRIVVKEPDSFGGCGQLFRNVLLCKSHRPNKTKPLRAKSLSPGGVYPQSRGKGHNLRGHIRK
VLISMSVRIRTKIGTYALFVLAGFQLVGGLASAQIIPTRDSLAKPSQAARDLLAAPTVGPIAQVPSTPQPDAADPDGATT
LDETLVEGRLAPRRSTPVFTITREDIQKKAAVNLADALRGVPGFAINDAGRGADFHNGSYYRGATVNQSALLINGRQIKT
GLNSNHGATDYNSIPVEGIKRIELLGPGAGTTLYGSDVIGGVINIITEEGPAVPTFSGSAEYGSYGESIYRTSYGGTSER
LKYNFGYQSYGATNNFPVPVGSTNRGEDGRLMNADMYTASYQGSATYTFDRRNNLTFDLFKNLSRKGLIIGNSKDRLDRD
GLNVGLTWRTLLGEGNDSVLVTTLGYVDDFFSTYGPVQTDYFKAVQLASKFYQARIDHTWRTSPGNTLRWGVDTRHNTLL
STQNNTSPDPIFFGLGGTTDTAITNTGIFALDTWQIVEGLQLDLGLRQTFDSKFGSYLNPSAGLRWQIIPEVALRASYAS
VQRNPGPDFLFLPDAAEGFLPNPDLKPERGSVYNAGFDLRFADNLRGEVTYFGSLIQDRIGNGPLPADPTLTQRTNIGAV
GTNGVEAGIKWQIDPQWSSYLSYTYTKIKIEEGRSLGLLRFLPESVGQVGVGYDNQGLQVNVFVNYNSGAARTNALTSYT
TPFATIDLRAAIPINRALALTVYLANLADVQYERVNTFYSPGLTYRVGLQTSF
>Mature_773_residues
MEAPLDNGCCDLLAIYSRTRIVVKEPDSFGGCGQLFRNVLLCKSHRPNKTKPLRAKSLSPGGVYPQSRGKGHNLRGHIRK
VLISMSVRIRTKIGTYALFVLAGFQLVGGLASAQIIPTRDSLAKPSQAARDLLAAPTVGPIAQVPSTPQPDAADPDGATT
LDETLVEGRLAPRRSTPVFTITREDIQKKAAVNLADALRGVPGFAINDAGRGADFHNGSYYRGATVNQSALLINGRQIKT
GLNSNHGATDYNSIPVEGIKRIELLGPGAGTTLYGSDVIGGVINIITEEGPAVPTFSGSAEYGSYGESIYRTSYGGTSER
LKYNFGYQSYGATNNFPVPVGSTNRGEDGRLMNADMYTASYQGSATYTFDRRNNLTFDLFKNLSRKGLIIGNSKDRLDRD
GLNVGLTWRTLLGEGNDSVLVTTLGYVDDFFSTYGPVQTDYFKAVQLASKFYQARIDHTWRTSPGNTLRWGVDTRHNTLL
STQNNTSPDPIFFGLGGTTDTAITNTGIFALDTWQIVEGLQLDLGLRQTFDSKFGSYLNPSAGLRWQIIPEVALRASYAS
VQRNPGPDFLFLPDAAEGFLPNPDLKPERGSVYNAGFDLRFADNLRGEVTYFGSLIQDRIGNGPLPADPTLTQRTNIGAV
GTNGVEAGIKWQIDPQWSSYLSYTYTKIKIEEGRSLGLLRFLPESVGQVGVGYDNQGLQVNVFVNYNSGAARTNALTSYT
TPFATIDLRAAIPINRALALTVYLANLADVQYERVNTFYSPGLTYRVGLQTSF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=670, Percent_Identity=23.5820895522388, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1790405, Length=180, Percent_Identity=29.4444444444444, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 83959; Mature: 83959

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAPLDNGCCDLLAIYSRTRIVVKEPDSFGGCGQLFRNVLLCKSHRPNKTKPLRAKSLSP
CCCCCCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCC
GGVYPQSRGKGHNLRGHIRKVLISMSVRIRTKIGTYALFVLAGFQLVGGLASAQIIPTRD
CCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHCCHHCCEEEECCH
SLAKPSQAARDLLAAPTVGPIAQVPSTPQPDAADPDGATTLDETLVEGRLAPRRSTPVFT
HHCCHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEE
ITREDIQKKAAVNLADALRGVPGFAINDAGRGADFHNGSYYRGATVNQSALLINGRQIKT
EEHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEECCCCCCCEEEEECEEEEC
GLNSNHGATDYNSIPVEGIKRIELLGPGAGTTLYGSDVIGGVINIITEEGPAVPTFSGSA
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCHHHHHHHHHEECCCCCCCCCCCCC
EYGSYGESIYRTSYGGTSERLKYNFGYQSYGATNNFPVPVGSTNRGEDGRLMNADMYTAS
CCCCCCCHHEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECEEEEEE
YQGSATYTFDRRNNLTFDLFKNLSRKGLIIGNSKDRLDRDGLNVGLTWRTLLGEGNDSVL
CCCCEEEEEECCCCCCHHHHHCCCCCEEEEECCHHCCCCCCCEEEEEEEEEECCCCCCEE
VTTLGYVDDFFSTYGPVQTDYFKAVQLASKFYQARIDHTWRTSPGNTLRWGVDTRHNTLL
EEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCCCCCCEEE
STQNNTSPDPIFFGLGGTTDTAITNTGIFALDTWQIVEGLQLDLGLRQTFDSKFGSYLNP
ECCCCCCCCCEEEECCCCCCCEEECCCEEEEEHHHHHCCCEECCCHHHHHHHHHCCCCCC
SAGLRWQIIPEVALRASYASVQRNPGPDFLFLPDAAEGFLPNPDLKPERGSVYNAGFDLR
CCCCEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEECCEEEE
FADNLRGEVTYFGSLIQDRIGNGPLPADPTLTQRTNIGAVGTNGVEAGIKWQIDPQWSSY
ECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHH
LSYTYTKIKIEEGRSLGLLRFLPESVGQVGVGYDNQGLQVNVFVNYNSGAARTNALTSYT
EEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEECC
TPFATIDLRAAIPINRALALTVYLANLADVQYERVNTFYSPGLTYRVGLQTSF
CCEEEEEEEEECCCCHHEEEEHHHHHHHHHHHHHHHHEECCCCEEEEEEEECC
>Mature Secondary Structure
MEAPLDNGCCDLLAIYSRTRIVVKEPDSFGGCGQLFRNVLLCKSHRPNKTKPLRAKSLSP
CCCCCCCCHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCC
GGVYPQSRGKGHNLRGHIRKVLISMSVRIRTKIGTYALFVLAGFQLVGGLASAQIIPTRD
CCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHCCHHCCEEEECCH
SLAKPSQAARDLLAAPTVGPIAQVPSTPQPDAADPDGATTLDETLVEGRLAPRRSTPVFT
HHCCHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCEEE
ITREDIQKKAAVNLADALRGVPGFAINDAGRGADFHNGSYYRGATVNQSALLINGRQIKT
EEHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEECCCCCCCEEEEECEEEEC
GLNSNHGATDYNSIPVEGIKRIELLGPGAGTTLYGSDVIGGVINIITEEGPAVPTFSGSA
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEECCHHHHHHHHHEECCCCCCCCCCCCC
EYGSYGESIYRTSYGGTSERLKYNFGYQSYGATNNFPVPVGSTNRGEDGRLMNADMYTAS
CCCCCCCHHEEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECEEEEEE
YQGSATYTFDRRNNLTFDLFKNLSRKGLIIGNSKDRLDRDGLNVGLTWRTLLGEGNDSVL
CCCCEEEEEECCCCCCHHHHHCCCCCEEEEECCHHCCCCCCCEEEEEEEEEECCCCCCEE
VTTLGYVDDFFSTYGPVQTDYFKAVQLASKFYQARIDHTWRTSPGNTLRWGVDTRHNTLL
EEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEECCCCCCCEEE
STQNNTSPDPIFFGLGGTTDTAITNTGIFALDTWQIVEGLQLDLGLRQTFDSKFGSYLNP
ECCCCCCCCCEEEECCCCCCCEEECCCEEEEEHHHHHCCCEECCCHHHHHHHHHCCCCCC
SAGLRWQIIPEVALRASYASVQRNPGPDFLFLPDAAEGFLPNPDLKPERGSVYNAGFDLR
CCCCEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCEEECCEEEE
FADNLRGEVTYFGSLIQDRIGNGPLPADPTLTQRTNIGAVGTNGVEAGIKWQIDPQWSSY
ECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHH
LSYTYTKIKIEEGRSLGLLRFLPESVGQVGVGYDNQGLQVNVFVNYNSGAARTNALTSYT
EEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCEECC
TPFATIDLRAAIPINRALALTVYLANLADVQYERVNTFYSPGLTYRVGLQTSF
CCEEEEEEEEECCCCHHEEEEHHHHHHHHHHHHHHHHEECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]