| Definition | Gloeobacter violaceus PCC 7421 chromosome, complete genome. |
|---|---|
| Accession | NC_005125 |
| Length | 4,659,019 |
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The map label for this gene is ftsI [H]
Identifier: 37522498
GI number: 37522498
Start: 3125411
End: 3127252
Strand: Direct
Name: ftsI [H]
Synonym: glr2929
Alternate gene names: 37522498
Gene position: 3125411-3127252 (Clockwise)
Preceding gene: 37522497
Following gene: 37522502
Centisome position: 67.08
GC content: 67.26
Gene sequence:
>1842_bases ATGCGTTCGATCCGGCGGCAAACCACCTCCCGCCTGTGGCTGGTGGGCATCGGTGTACTCGCGGCGGCGGGCGGTCTGGG CTACCGCCTCTACGATCTGCAGGTCACCCAGGCGAGCACCCTCCAGGAACGTGCCGCCCTCCAGCGCGAGCGCACGGTCA AATCCGAGCGGCCCCGGGCAGGAATCGTCGATCGGCGCGGGGTGGCCCTGGCCCTCGATGAGCCGATTTTTGATCTCTAC GCCCACCCGTTTTTGATCGACGCGGAGGCAAAATTGCTCGCCTCGCGCCAGGCTTCCAGACAAAAAGGCGTCGATCGCGA GGCGCTGGAGGCCAAGCTTGCCGCCCAGCACCGTCAGGCGCTGCGCTCCGAGATGGCCCTGGCCCTCGCCCAGGCCACCG GTCGGCCCGCGGCCGAAATCGCCGCCCGCCTCACTGAAAATCGCCGCACCGTCGCCCTTGCCCGCGGCCTGGGCGAAAAT GCCCGCGAGCGCATCGTGCAGGCGAAGCTGCCGGGGTTGGAGTTCGGTTCGCGCCGCCGCCGCTTCTACCCGGACGGGGC CAACAGCGCTGCGTTGGTGGGCTTTCTCAACTACGAAGGCCAGGGCCAGGGGGGCGTCGAGCAGTTCTACCACAAGCGCC TCACCGGCGCCTCGTCGAGCTACCCGGTCACCCTCGGCCCCGGGGGGCTGCCGCTGGCAAGCACCCTGCCCACCGAGGCG TTCGAAGGCTTCGAGCCCGGCCGTCTGGCCCTCACCATCGACGCGCGCGTGCAGCGTGCCGCCCGCCTTGCCCTGGAGCG CGGCGTCGAGGCCAACCGCGTCACTCGGGGTGCCGCCATTGTGCTGGAGCCCCAGAGCGGCGAAATTCTGGCGATGGCGG TGAGCCCCAGTTTCGACAACAACCGCTACGGCGAATTTCCGCCCGCCCATTTCAAGAACTGGGCGGTGAGCGACCTGTAC GAACCAGGATCGACATTTAAGCCGGTCAACGTCGCCCTCGCCCTCAGCGCCGGGGCCATTCGCCCCGACACCGTCGTCAA CGACTCCGGTTCGATGAGTTTTGGCCGCTATACGCTCAGCAACTACGACCGGCGGGCGCGCGGGGCGATTTCGGTCACCA AGGTGCTGATGGTCTCCAGCAACATCGGCATGATCCGCCTGATGCAAAAAATGCCGCCCACCGCGTACTACGACAAACTG CGCGAAATCGGCATCGGGGGAGCCGGCGGCGTCGATCTGCCGGGCGAAACGCGCGGGATCATCACCAACCGCACCCAGTT CGCCAAATACCCGGTGCAGGTGGCGACGGTGGCCTTCGGCCAGGGGGTGGCCCTCACGCCTTTGCAACTGGCAAGCCTGC ACGGGGCGATTGCCAACGGCGGCATGGCCATCCAGCCCCACCTCGTGCGCGCCTTCGAGAATGACGAAGGCCAGGTGCTC TGGAAACCGGAGCACCGATCGACCAAGCGCATCTTCACCTCCGAGGCGACCGTCGCCGTGCGCGAGATGATGATGCACGT CGTCGAAGAGGGCACCGGCAAACCGGCGCGCATCCCGGGCTACCGCATCGGCGGCAAGACCGGCACCGCCCAAAAAGCCA ACATCGGCGGGCGCGGCTACCTGGCGGGCAAAAAGATCACCAGCTTCGTGGGCTATCTGCCGGCGCGCAACCCACGCTAC GTGGTGCTGGTGGTGCTGGATGAACCCAAGTCCGGTAACGCCTTCGGCTCCACCACCGCCGCTCCCATCGTGCGCGAAAT CTGCCAGGAGCTGATTTCCTACGGCAACCTCCCCCCGAGTCACCCGCAGGAGTTGCTCGCCGCCGCGCCCAAAAAACCGT AG
Upstream 100 bases:
>100_bases CCCAGGCGCTCAGCGTACCGGCCGCTCCCGAGCGTCCCCTCAAGCCGTTGCCCCAGGCTGCGGCCCCTGATCTGGCCCTT GCCATTCCGGCGGGCTACTG
Downstream 100 bases:
>100_bases TAGCTTACCACCGTACCGCCGTAGACCCGCCGATCGAGTCGCACCAGAGAACCCACGGCCTCGGGCAAATCCGGCAAATC TTCGCCGTGCTCGGCAGCCA
Product: penicillin-binding protein
Products: NA
Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]
Number of amino acids: Translated: 613; Mature: 613
Protein sequence:
>613_residues MRSIRRQTTSRLWLVGIGVLAAAGGLGYRLYDLQVTQASTLQERAALQRERTVKSERPRAGIVDRRGVALALDEPIFDLY AHPFLIDAEAKLLASRQASRQKGVDREALEAKLAAQHRQALRSEMALALAQATGRPAAEIAARLTENRRTVALARGLGEN ARERIVQAKLPGLEFGSRRRRFYPDGANSAALVGFLNYEGQGQGGVEQFYHKRLTGASSSYPVTLGPGGLPLASTLPTEA FEGFEPGRLALTIDARVQRAARLALERGVEANRVTRGAAIVLEPQSGEILAMAVSPSFDNNRYGEFPPAHFKNWAVSDLY EPGSTFKPVNVALALSAGAIRPDTVVNDSGSMSFGRYTLSNYDRRARGAISVTKVLMVSSNIGMIRLMQKMPPTAYYDKL REIGIGGAGGVDLPGETRGIITNRTQFAKYPVQVATVAFGQGVALTPLQLASLHGAIANGGMAIQPHLVRAFENDEGQVL WKPEHRSTKRIFTSEATVAVREMMMHVVEEGTGKPARIPGYRIGGKTGTAQKANIGGRGYLAGKKITSFVGYLPARNPRY VVLVVLDEPKSGNAFGSTTAAPIVREICQELISYGNLPPSHPQELLAAAPKKP
Sequences:
>Translated_613_residues MRSIRRQTTSRLWLVGIGVLAAAGGLGYRLYDLQVTQASTLQERAALQRERTVKSERPRAGIVDRRGVALALDEPIFDLY AHPFLIDAEAKLLASRQASRQKGVDREALEAKLAAQHRQALRSEMALALAQATGRPAAEIAARLTENRRTVALARGLGEN ARERIVQAKLPGLEFGSRRRRFYPDGANSAALVGFLNYEGQGQGGVEQFYHKRLTGASSSYPVTLGPGGLPLASTLPTEA FEGFEPGRLALTIDARVQRAARLALERGVEANRVTRGAAIVLEPQSGEILAMAVSPSFDNNRYGEFPPAHFKNWAVSDLY EPGSTFKPVNVALALSAGAIRPDTVVNDSGSMSFGRYTLSNYDRRARGAISVTKVLMVSSNIGMIRLMQKMPPTAYYDKL REIGIGGAGGVDLPGETRGIITNRTQFAKYPVQVATVAFGQGVALTPLQLASLHGAIANGGMAIQPHLVRAFENDEGQVL WKPEHRSTKRIFTSEATVAVREMMMHVVEEGTGKPARIPGYRIGGKTGTAQKANIGGRGYLAGKKITSFVGYLPARNPRY VVLVVLDEPKSGNAFGSTTAAPIVREICQELISYGNLPPSHPQELLAAAPKKP >Mature_613_residues MRSIRRQTTSRLWLVGIGVLAAAGGLGYRLYDLQVTQASTLQERAALQRERTVKSERPRAGIVDRRGVALALDEPIFDLY AHPFLIDAEAKLLASRQASRQKGVDREALEAKLAAQHRQALRSEMALALAQATGRPAAEIAARLTENRRTVALARGLGEN ARERIVQAKLPGLEFGSRRRRFYPDGANSAALVGFLNYEGQGQGGVEQFYHKRLTGASSSYPVTLGPGGLPLASTLPTEA FEGFEPGRLALTIDARVQRAARLALERGVEANRVTRGAAIVLEPQSGEILAMAVSPSFDNNRYGEFPPAHFKNWAVSDLY EPGSTFKPVNVALALSAGAIRPDTVVNDSGSMSFGRYTLSNYDRRARGAISVTKVLMVSSNIGMIRLMQKMPPTAYYDKL REIGIGGAGGVDLPGETRGIITNRTQFAKYPVQVATVAFGQGVALTPLQLASLHGAIANGGMAIQPHLVRAFENDEGQVL WKPEHRSTKRIFTSEATVAVREMMMHVVEEGTGKPARIPGYRIGGKTGTAQKANIGGRGYLAGKKITSFVGYLPARNPRY VVLVVLDEPKSGNAFGSTTAAPIVREICQELISYGNLPPSHPQELLAAAPKKP
Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]
COG id: COG0768
COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2
Gene ontology:
Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1786272, Length=591, Percent_Identity=29.9492385786802, Blast_Score=223, Evalue=3e-59, Organism=Escherichia coli, GI1786854, Length=644, Percent_Identity=24.5341614906832, Blast_Score=130, Evalue=2e-31,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR005311 - InterPro: IPR001460 [H]
Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]
EC number: =2.4.1.129 [H]
Molecular weight: Translated: 66140; Mature: 66140
Theoretical pI: Translated: 10.52; Mature: 10.52
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRSIRRQTTSRLWLVGIGVLAAAGGLGYRLYDLQVTQASTLQERAALQRERTVKSERPRA CCCHHHHHHCEEHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCC GIVDRRGVALALDEPIFDLYAHPFLIDAEAKLLASRQASRQKGVDREALEAKLAAQHRQA CCCCCCCEEEEECCCHHHHHCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH LRSEMALALAQATGRPAAEIAARLTENRRTVALARGLGENARERIVQAKLPGLEFGSRRR HHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEHHCCCHHHHHHHHHHCCCCCCCCCCCC RFYPDGANSAALVGFLNYEGQGQGGVEQFYHKRLTGASSSYPVTLGPGGLPLASTLPTEA CCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCHHH FEGFEPGRLALTIDARVQRAARLALERGVEANRVTRGAAIVLEPQSGEILAMAVSPSFDN HCCCCCCEEEEEEHHHHHHHHHHHHHCCCCHHEECCCEEEEEECCCCCEEEEEECCCCCC NRYGEFPPAHFKNWAVSDLYEPGSTFKPVNVALALSAGAIRPDTVVNDSGSMSFGRYTLS CCCCCCCCHHHCCCCHHHHCCCCCCCCCEEEEEEEECCCCCCCCEECCCCCCCCCEEEHH NYDRRARGAISVTKVLMVSSNIGMIRLMQKMPPTAYYDKLREIGIGGAGGVDLPGETRGI CCCHHHCCHHHHEEEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCE ITNRTQFAKYPVQVATVAFGQGVALTPLQLASLHGAIANGGMAIQPHLVRAFENDEGQVL EECCHHHHHCCEEEEEEEECCCCEECHHHHHHHHHHHHCCCEEECCHHHEEEECCCCCEE WKPEHRSTKRIFTSEATVAVREMMMHVVEEGTGKPARIPGYRIGGKTGTAQKANIGGRGY ECCCCCCCHHEECCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCEE LAGKKITSFVGYLPARNPRYVVLVVLDEPKSGNAFGSTTAAPIVREICQELISYGNLPPS ECHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC HPQELLAAAPKKP CHHHHHHCCCCCC >Mature Secondary Structure MRSIRRQTTSRLWLVGIGVLAAAGGLGYRLYDLQVTQASTLQERAALQRERTVKSERPRA CCCHHHHHHCEEHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCC GIVDRRGVALALDEPIFDLYAHPFLIDAEAKLLASRQASRQKGVDREALEAKLAAQHRQA CCCCCCCEEEEECCCHHHHHCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH LRSEMALALAQATGRPAAEIAARLTENRRTVALARGLGENARERIVQAKLPGLEFGSRRR HHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEHHCCCHHHHHHHHHHCCCCCCCCCCCC RFYPDGANSAALVGFLNYEGQGQGGVEQFYHKRLTGASSSYPVTLGPGGLPLASTLPTEA CCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCHHH FEGFEPGRLALTIDARVQRAARLALERGVEANRVTRGAAIVLEPQSGEILAMAVSPSFDN HCCCCCCEEEEEEHHHHHHHHHHHHHCCCCHHEECCCEEEEEECCCCCEEEEEECCCCCC NRYGEFPPAHFKNWAVSDLYEPGSTFKPVNVALALSAGAIRPDTVVNDSGSMSFGRYTLS CCCCCCCCHHHCCCCHHHHCCCCCCCCCEEEEEEEECCCCCCCCEECCCCCCCCCEEEHH NYDRRARGAISVTKVLMVSSNIGMIRLMQKMPPTAYYDKLREIGIGGAGGVDLPGETRGI CCCHHHCCHHHHEEEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCE ITNRTQFAKYPVQVATVAFGQGVALTPLQLASLHGAIANGGMAIQPHLVRAFENDEGQVL EECCHHHHHCCEEEEEEEECCCCEECHHHHHHHHHHHHCCCEEECCHHHEEEECCCCCEE WKPEHRSTKRIFTSEATVAVREMMMHVVEEGTGKPARIPGYRIGGKTGTAQKANIGGRGY ECCCCCCCHHEECCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCEE LAGKKITSFVGYLPARNPRYVVLVVLDEPKSGNAFGSTTAAPIVREICQELISYGNLPPS ECHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC HPQELLAAAPKKP CHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 12522265 [H]