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The map label for this gene is atpD

Identifier: 37522475

GI number: 37522475

Start: 3102947

End: 3103504

Strand: Reverse

Name: atpD

Synonym: gvip399

Alternate gene names: 37522475

Gene position: 3103504-3102947 (Counterclockwise)

Preceding gene: 37522476

Following gene: 37522474

Centisome position: 66.61

GC content: 61.11

Gene sequence:

>558_bases
ATGCAGCAAGGCAAAGACAGCGAACAGATAGCCCAGCGCTACGCCGAGGCACTCAAAGAACTCGCCCTTTCCGAGACGGG
GCTTCTGGAGCAGTTTGGCAACGACACCGACGGAATGCTCCAGGTGATGGAGGAGTCTCCCGATTTCGAGCGCTTCCTGG
TAGTGCCCATCATCGCCATGGCGGACAAGAAGCGCCTGCTGGTCGAAGCTTTTGGCGGCAAGGTGCATCCCTACATGCTC
AACTTTTTGCAGTTGATGGTAGACCGGCGGCGGATCGCGCTTTTGCGCCCCGTCTGCACGAGCTACCAGCGCATCTTGCG
CGAGCTGCAGCAGACGACCCTGGCGGAGGTGATCTCGGCGGTGCCCCTGAGTGAAGAGCAGGCGAGCGCTCTCATCGAGC
GCATTCGTCGGCGCACCGCTGCTGTGCGCGTCGAGTTGCGCCGGCGCGTCGATCCAGAACTCTTGGGCGGCATGATCATC
AAGATTGGCGACGAAGTAATCGACGCCAGTCTGCGCGGCCAGCTGCGCAAGCTCACCTTGCAGCTCACGCTTTCTTGA

Upstream 100 bases:

>100_bases
CGACGCCCTCGCCCGCCTGCGCGAGCGCCTGCCCGGCGAACTCGACGAGGCCACCCAGCGCCGCCTGCTCGATCGCAGCA
TCCAATTACTGGACTAGACC

Downstream 100 bases:

>100_bases
AAATCGAGAGGTAGCCATGTTCACGATTCGCCCGGACGAAATCAGCTCCGTCATCCGCGATCAAATCCAGAAGTACAACA
CCGAACTGCAGGTGACCAAC

Product: ATP synthase delta chain of CF(1)

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MQQGKDSEQIAQRYAEALKELALSETGLLEQFGNDTDGMLQVMEESPDFERFLVVPIIAMADKKRLLVEAFGGKVHPYML
NFLQLMVDRRRIALLRPVCTSYQRILRELQQTTLAEVISAVPLSEEQASALIERIRRRTAAVRVELRRRVDPELLGGMII
KIGDEVIDASLRGQLRKLTLQLTLS

Sequences:

>Translated_185_residues
MQQGKDSEQIAQRYAEALKELALSETGLLEQFGNDTDGMLQVMEESPDFERFLVVPIIAMADKKRLLVEAFGGKVHPYML
NFLQLMVDRRRIALLRPVCTSYQRILRELQQTTLAEVISAVPLSEEQASALIERIRRRTAAVRVELRRRVDPELLGGMII
KIGDEVIDASLRGQLRKLTLQLTLS
>Mature_185_residues
MQQGKDSEQIAQRYAEALKELALSETGLLEQFGNDTDGMLQVMEESPDFERFLVVPIIAMADKKRLLVEAFGGKVHPYML
NFLQLMVDRRRIALLRPVCTSYQRILRELQQTTLAEVISAVPLSEEQASALIERIRRRTAAVRVELRRRVDPELLGGMII
KIGDEVIDASLRGQLRKLTLQLTLS

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Caenorhabditis elegans, GI71984710, Length=168, Percent_Identity=27.9761904761905, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71984717, Length=168, Percent_Identity=27.9761904761905, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24647054, Length=175, Percent_Identity=25.7142857142857, Blast_Score=63, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_GLOVI (Q7NCS2)

Other databases:

- EMBL:   BA000045
- RefSeq:   NP_925852.1
- ProteinModelPortal:   Q7NCS2
- SMR:   Q7NCS2
- GeneID:   2601307
- GenomeReviews:   BA000045_GR
- NMPDR:   fig|251221.1.peg.2906
- HOGENOM:   HBG668108
- OMA:   MSTNAIA
- BioCyc:   GVIO251221:GLL2906-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 21019; Mature: 21019

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQGKDSEQIAQRYAEALKELALSETGLLEQFGNDTDGMLQVMEESPDFERFLVVPIIAM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHH
ADKKRLLVEAFGGKVHPYMLNFLQLMVDRRRIALLRPVCTSYQRILRELQQTTLAEVISA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPLSEEQASALIERIRRRTAAVRVELRRRVDPELLGGMIIKIGDEVIDASLRGQLRKLTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
QLTLS
EEECC
>Mature Secondary Structure
MQQGKDSEQIAQRYAEALKELALSETGLLEQFGNDTDGMLQVMEESPDFERFLVVPIIAM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHH
ADKKRLLVEAFGGKVHPYMLNFLQLMVDRRRIALLRPVCTSYQRILRELQQTTLAEVISA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPLSEEQASALIERIRRRTAAVRVELRRRVDPELLGGMIIKIGDEVIDASLRGQLRKLTL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
QLTLS
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14621292