Click here to switch to the map view.

The map label for this gene is qorA [H]

Identifier: 37522428

GI number: 37522428

Start: 3048442

End: 3049443

Strand: Direct

Name: qorA [H]

Synonym: glr2859

Alternate gene names: 37522428

Gene position: 3048442-3049443 (Clockwise)

Preceding gene: 37522420

Following gene: 37522431

Centisome position: 65.43

GC content: 67.07

Gene sequence:

>1002_bases
ATGCGCGTCGTTCAGTTTCGCGTTTTCGGAGGATCTGAGGTGCTCGAAGTCGCCGATGCGGTGCTCCCGCAACCCCACCG
CGGCGAAATCGCGGTGGATGTCCGCTACGCGGGCGTCAATTTCGCCGACATCATGTTGCGGCGGGGTGCCCTTGCGGGCA
CGCCGTTGCCCACAGTGCCCGGACTCGAAGTCGCCGGCACCGTCGCCGAGATTGGGCCCGGGGTGAGCGGATTTGCTTAC
GGCGAGCCGGTTGCGGCCTTTTCATGGACACCCGGCAAAGCGATGGGCGGCTATGCGCAGCGGGTTGTGCTCGACTCCCG
TCTCGCCGTGCCGCTGCGCAGGGCCGAGCGGGAACTTAGATACGAAGAAGGGGCCGGCTTTGCCTGCGCCGCCGTCACCG
CTTACCAGTTGCTGGCTGATGTTGCCCGCCTGCGACCGGGCGAAACCGTGCTCGTCCAATCCGCCGCCGGCGGGGTGGGA
TCGCTTGCGGTCCAGTTCGCCCGCGCCCTCGGTGCTGCGCGTATTTTCGGTGTGGTCGGCTCTGCGTCTAAAACAGAAGC
CGCCCTGGCCGCCGGTTGCGACCGGGTTGTGCTGCGCGAAGGCTGGATAGAAGCGGTACGCTCGTTCACCGGCGGCCGGG
GCGTGGACATCGCGCTTGAGAGCGTCGGGGGCGACAGCCTGGCTGCTTGTTTGCAAGTGCTCGCCCCGTTCGGGCGCGTC
GCGTATTTCGGCGACGCTTCCGGGTCCGGTCCGATTTCTCTGCCGGCGTTTGACCTGTGGTTCGGGACAAAGGGCGTGCT
CGGATACAACATTGGCGGACTCGCCGCCGCTTCGCCCGAAAGTTGGAACGGTGCGGCCAATCGCGCCATCGAACTGATCG
CCAACGGCGCGGTGCGGCTTGCGCCGACGCGGATCTACCCGCTGGAGCGGGCGGCCGAGGCCCAGCATGCCCTCGAAACG
CGCGCCTCGACCGGCAAGATGTTGCTCCAGGTCACAAGCTGA

Upstream 100 bases:

>100_bases
GCTGTCTTTCCGAAAAGCCAGATGATTGCGCGGGTAGTTTCTGGTAGCTCTGGGGAAAGGCCGCTTGCGGTCTCTGACTC
GAACCTAGAGGGGTATGACC

Downstream 100 bases:

>100_bases
GGGGCGAGGAAAATCCCCGGCCCGCTCAGCGTCTTGCCGGGGGCGGGGGGGCGGGCACCGGGAGCCTGTCCCAGGGCGGC
GGATCTGCGAAGGTTCTGAC

Product: oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MRVVQFRVFGGSEVLEVADAVLPQPHRGEIAVDVRYAGVNFADIMLRRGALAGTPLPTVPGLEVAGTVAEIGPGVSGFAY
GEPVAAFSWTPGKAMGGYAQRVVLDSRLAVPLRRAERELRYEEGAGFACAAVTAYQLLADVARLRPGETVLVQSAAGGVG
SLAVQFARALGAARIFGVVGSASKTEAALAAGCDRVVLREGWIEAVRSFTGGRGVDIALESVGGDSLAACLQVLAPFGRV
AYFGDASGSGPISLPAFDLWFGTKGVLGYNIGGLAAASPESWNGAANRAIELIANGAVRLAPTRIYPLERAAEAQHALET
RASTGKMLLQVTS

Sequences:

>Translated_333_residues
MRVVQFRVFGGSEVLEVADAVLPQPHRGEIAVDVRYAGVNFADIMLRRGALAGTPLPTVPGLEVAGTVAEIGPGVSGFAY
GEPVAAFSWTPGKAMGGYAQRVVLDSRLAVPLRRAERELRYEEGAGFACAAVTAYQLLADVARLRPGETVLVQSAAGGVG
SLAVQFARALGAARIFGVVGSASKTEAALAAGCDRVVLREGWIEAVRSFTGGRGVDIALESVGGDSLAACLQVLAPFGRV
AYFGDASGSGPISLPAFDLWFGTKGVLGYNIGGLAAASPESWNGAANRAIELIANGAVRLAPTRIYPLERAAEAQHALET
RASTGKMLLQVTS
>Mature_333_residues
MRVVQFRVFGGSEVLEVADAVLPQPHRGEIAVDVRYAGVNFADIMLRRGALAGTPLPTVPGLEVAGTVAEIGPGVSGFAY
GEPVAAFSWTPGKAMGGYAQRVVLDSRLAVPLRRAERELRYEEGAGFACAAVTAYQLLADVARLRPGETVLVQSAAGGVG
SLAVQFARALGAARIFGVVGSASKTEAALAAGCDRVVLREGWIEAVRSFTGGRGVDIALESVGGDSLAACLQVLAPFGRV
AYFGDASGSGPISLPAFDLWFGTKGVLGYNIGGLAAASPESWNGAANRAIELIANGAVRLAPTRIYPLERAAEAQHALET
RASTGKMLLQVTS

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=319, Percent_Identity=30.0940438871473, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI194239674, Length=334, Percent_Identity=30.2395209580838, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI13236495, Length=334, Percent_Identity=30.2395209580838, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI24308257, Length=349, Percent_Identity=27.2206303724928, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI22538446, Length=342, Percent_Identity=31.8713450292398, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI22538444, Length=342, Percent_Identity=31.8713450292398, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI194239676, Length=218, Percent_Identity=33.4862385321101, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI41872631, Length=314, Percent_Identity=29.6178343949045, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI28557745, Length=333, Percent_Identity=26.1261261261261, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI197927207, Length=195, Percent_Identity=29.7435897435897, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1790485, Length=337, Percent_Identity=31.4540059347181, Blast_Score=143, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17507255, Length=335, Percent_Identity=26.2686567164179, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319520, Length=339, Percent_Identity=27.4336283185841, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319621, Length=192, Percent_Identity=31.25, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=189, Percent_Identity=31.2169312169312, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324486, Length=197, Percent_Identity=30.9644670050761, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920632, Length=322, Percent_Identity=27.3291925465839, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI221330659, Length=322, Percent_Identity=27.3291925465839, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24581345, Length=316, Percent_Identity=27.2151898734177, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34397; Mature: 34397

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVQFRVFGGSEVLEVADAVLPQPHRGEIAVDVRYAGVNFADIMLRRGALAGTPLPTVP
CEEEEEEEECCCHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCC
GLEVAGTVAEIGPGVSGFAYGEPVAAFSWTPGKAMGGYAQRVVLDSRLAVPLRRAERELR
CCHHHCHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHH
YEEGAGFACAAVTAYQLLADVARLRPGETVLVQSAAGGVGSLAVQFARALGAARIFGVVG
HHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
SASKTEAALAAGCDRVVLREGWIEAVRSFTGGRGVDIALESVGGDSLAACLQVLAPFGRV
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCE
AYFGDASGSGPISLPAFDLWFGTKGVLGYNIGGLAAASPESWNGAANRAIELIANGAVRL
EEECCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCEEE
APTRIYPLERAAEAQHALETRASTGKMLLQVTS
ECCEECCHHHHHHHHHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure
MRVVQFRVFGGSEVLEVADAVLPQPHRGEIAVDVRYAGVNFADIMLRRGALAGTPLPTVP
CEEEEEEEECCCHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCC
GLEVAGTVAEIGPGVSGFAYGEPVAAFSWTPGKAMGGYAQRVVLDSRLAVPLRRAERELR
CCHHHCHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHH
YEEGAGFACAAVTAYQLLADVARLRPGETVLVQSAAGGVGSLAVQFARALGAARIFGVVG
HHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
SASKTEAALAAGCDRVVLREGWIEAVRSFTGGRGVDIALESVGGDSLAACLQVLAPFGRV
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCE
AYFGDASGSGPISLPAFDLWFGTKGVLGYNIGGLAAASPESWNGAANRAIELIANGAVRL
EEECCCCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCEEE
APTRIYPLERAAEAQHALETRASTGKMLLQVTS
ECCEECCHHHHHHHHHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]