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The map label for this gene is yccK [H]

Identifier: 37522410

GI number: 37522410

Start: 3028663

End: 3029646

Strand: Reverse

Name: yccK [H]

Synonym: gll2841

Alternate gene names: 37522410

Gene position: 3029646-3028663 (Counterclockwise)

Preceding gene: 37522421

Following gene: 37522409

Centisome position: 65.03

GC content: 64.84

Gene sequence:

>984_bases
ATGCAAATGCGCCGATTGGGAAAAGACGGCCCACAGGTTTCGGCAATGGGTTTAGGCTGCATGGGCATCTCCGATGCCTA
CGGCACACGCGACGAGCAAGAAGCGCTCGCCACGCTGCACCGGGCCATCGATTTGGGGATCAACTTTCTCGACACTGCCG
ACGTGTACGGCCAGGGCCATAACGAACAGTTTGTCGGCCGGGCCATCCGCACTCGGCGCGACCGGGTGTGCCTAGCCACC
AAGTTCGGCCTGTTGCGCGACGCCCAGGGCCGTCTGACGGGGGTGTGCGGCACCCCGGCCTACGTGCGCTCCGCCTGCGA
AGCGAGTCTGCGGCGCCTGGGAATCGACACGATCGACCTTTACTACCAGCACCGCCTCGACCGGACGACCCCGATCGAAC
AGACCGTGGAGGCGCTGGCGGCACTGGTCCGGGAGGGCAAAATTCGCCACATCGGCCTCAGTGAGGTCGACGCCGAGACA
TTGCACCGGGCGGCCGCAATCCATCCGATTGCCGCTGTGCAAAGCGAATATTCCCTGTGGACCCGCGATCCGGAAGACGA
GATTCTGCCGGCCTGCCGGGAGTTGGGGGTGGGATTTGTGCCCTTCAGTCCCCTGGGGCGGGGTTTTCTGAGCGGCCGGG
TCAACAGCATGTCCGATCTGCCGCCTGAGGATTTCCGGCAGCGCCTGCCCCGCTTCCAGGGAGACAACTTCGAGCGAAAC
CGGGCCTGGGTCAGCCAGTTGGAAGCGTTGGCCGCCCAAAAAGGCTGTACACCAAGCCAGCTCGCCCTTGCCTGGGTGCT
GGCCCAGGGAGAAGACATCGTGCCCATTCCCGGGACGAAACGCCGGGCTTACCTGCAGGAAAACCTGGGGGCGCTGGAGA
TCCGTTGGGAAGCGGAGGAATTGGCTGCCCTGGAGCAGGTCGCTCCCCGCGGCGTCGCGGCTGGAGCGCGCTATCCCGAA
GCATTGCTGCAGATCACCCGTTGA

Upstream 100 bases:

>100_bases
CAGCTGCTGCAGATTCAAAAGTCTATCCGCTGCGGCCTGTCAAAATCTGGCGCTCACCGAGCGCAGAATCCACAACCAGA
AATTCAGGAGAACTGACAAG

Downstream 100 bases:

>100_bases
GATGTACTGCCCGAGGAGGGTGTGATGAGCGCAAGACCCTTTGACAACCTGATCGTGCCCAAACTGCTCCTTGCGGCCCT
GGCAGCGAGTGGGATCCAGG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MQMRRLGKDGPQVSAMGLGCMGISDAYGTRDEQEALATLHRAIDLGINFLDTADVYGQGHNEQFVGRAIRTRRDRVCLAT
KFGLLRDAQGRLTGVCGTPAYVRSACEASLRRLGIDTIDLYYQHRLDRTTPIEQTVEALAALVREGKIRHIGLSEVDAET
LHRAAAIHPIAAVQSEYSLWTRDPEDEILPACRELGVGFVPFSPLGRGFLSGRVNSMSDLPPEDFRQRLPRFQGDNFERN
RAWVSQLEALAAQKGCTPSQLALAWVLAQGEDIVPIPGTKRRAYLQENLGALEIRWEAEELAALEQVAPRGVAAGARYPE
ALLQITR

Sequences:

>Translated_327_residues
MQMRRLGKDGPQVSAMGLGCMGISDAYGTRDEQEALATLHRAIDLGINFLDTADVYGQGHNEQFVGRAIRTRRDRVCLAT
KFGLLRDAQGRLTGVCGTPAYVRSACEASLRRLGIDTIDLYYQHRLDRTTPIEQTVEALAALVREGKIRHIGLSEVDAET
LHRAAAIHPIAAVQSEYSLWTRDPEDEILPACRELGVGFVPFSPLGRGFLSGRVNSMSDLPPEDFRQRLPRFQGDNFERN
RAWVSQLEALAAQKGCTPSQLALAWVLAQGEDIVPIPGTKRRAYLQENLGALEIRWEAEELAALEQVAPRGVAAGARYPE
ALLQITR
>Mature_327_residues
MQMRRLGKDGPQVSAMGLGCMGISDAYGTRDEQEALATLHRAIDLGINFLDTADVYGQGHNEQFVGRAIRTRRDRVCLAT
KFGLLRDAQGRLTGVCGTPAYVRSACEASLRRLGIDTIDLYYQHRLDRTTPIEQTVEALAALVREGKIRHIGLSEVDAET
LHRAAAIHPIAAVQSEYSLWTRDPEDEILPACRELGVGFVPFSPLGRGFLSGRVNSMSDLPPEDFRQRLPRFQGDNFERN
RAWVSQLEALAAQKGCTPSQLALAWVLAQGEDIVPIPGTKRRAYLQENLGALEIRWEAEELAALEQVAPRGVAAGARYPE
ALLQITR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=311, Percent_Identity=31.1897106109325, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4504825, Length=308, Percent_Identity=31.1688311688312, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI27436964, Length=311, Percent_Identity=28.6173633440514, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI27436962, Length=311, Percent_Identity=28.6173633440514, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI27436966, Length=311, Percent_Identity=28.6173633440514, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI27436971, Length=328, Percent_Identity=28.0487804878049, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI223718702, Length=297, Percent_Identity=29.2929292929293, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI41327764, Length=281, Percent_Identity=30.2491103202847, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI41152114, Length=250, Percent_Identity=30, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=35, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788070, Length=310, Percent_Identity=34.5161290322581, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789375, Length=328, Percent_Identity=29.5731707317073, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787674, Length=306, Percent_Identity=30.3921568627451, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1788081, Length=284, Percent_Identity=29.2253521126761, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789199, Length=342, Percent_Identity=29.2397660818713, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17564128, Length=332, Percent_Identity=23.1927710843373, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=339, Percent_Identity=28.023598820059, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6323998, Length=342, Percent_Identity=27.1929824561404, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6319958, Length=303, Percent_Identity=28.0528052805281, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6325384, Length=339, Percent_Identity=26.8436578171091, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=308, Percent_Identity=26.9480519480519, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=258, Percent_Identity=26.7441860465116, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321052, Length=158, Percent_Identity=31.0126582278481, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24646155, Length=221, Percent_Identity=31.2217194570136, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24663317, Length=345, Percent_Identity=24.6376811594203, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24640980, Length=325, Percent_Identity=24.9230769230769, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45549126, Length=340, Percent_Identity=24.7058823529412, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24657054, Length=338, Percent_Identity=24.5562130177515, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI20129731, Length=342, Percent_Identity=25.1461988304094, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24646159, Length=222, Percent_Identity=28.8288288288288, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36116; Mature: 36116

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMRRLGKDGPQVSAMGLGCMGISDAYGTRDEQEALATLHRAIDLGINFLDTADVYGQGH
CCCHHCCCCCCCEEHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECHHHHCCCC
NEQFVGRAIRTRRDRVCLATKFGLLRDAQGRLTGVCGTPAYVRSACEASLRRLGIDTIDL
CHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCHHHHH
YYQHRLDRTTPIEQTVEALAALVREGKIRHIGLSEVDAETLHRAAAIHPIAAVQSEYSLW
HHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TRDPEDEILPACRELGVGFVPFSPLGRGFLSGRVNSMSDLPPEDFRQRLPRFQGDNFERN
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCHHH
RAWVSQLEALAAQKGCTPSQLALAWVLAQGEDIVPIPGTKRRAYLQENLGALEIRWEAEE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHCCCEEEEEECHHH
LAALEQVAPRGVAAGARYPEALLQITR
HHHHHHHCCCCHHCCCCCHHHHHHHCC
>Mature Secondary Structure
MQMRRLGKDGPQVSAMGLGCMGISDAYGTRDEQEALATLHRAIDLGINFLDTADVYGQGH
CCCHHCCCCCCCEEHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECHHHHCCCC
NEQFVGRAIRTRRDRVCLATKFGLLRDAQGRLTGVCGTPAYVRSACEASLRRLGIDTIDL
CHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCHHHHH
YYQHRLDRTTPIEQTVEALAALVREGKIRHIGLSEVDAETLHRAAAIHPIAAVQSEYSLW
HHHHHCCCCCCHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
TRDPEDEILPACRELGVGFVPFSPLGRGFLSGRVNSMSDLPPEDFRQRLPRFQGDNFERN
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCHHH
RAWVSQLEALAAQKGCTPSQLALAWVLAQGEDIVPIPGTKRRAYLQENLGALEIRWEAEE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCCCCCHHHHHHHCCCEEEEEECHHH
LAALEQVAPRGVAAGARYPEALLQITR
HHHHHHHCCCCHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]