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The map label for this gene is mdtA [H]

Identifier: 37522409

GI number: 37522409

Start: 3027409

End: 3028641

Strand: Reverse

Name: mdtA [H]

Synonym: gll2840

Alternate gene names: 37522409

Gene position: 3028641-3027409 (Counterclockwise)

Preceding gene: 37522410

Following gene: 37522408

Centisome position: 65.01

GC content: 65.13

Gene sequence:

>1233_bases
GTGATGAGCGCAAGACCCTTTGACAACCTGATCGTGCCCAAACTGCTCCTTGCGGCCCTGGCAGCGAGTGGGATCCAGGC
TTGCGGCTCGGCGCGCTCCGCCACCGAGACGGAGAAGCCGGCCGCTACCCCAGTCGCCTTAGCGACGGTCCGATCCTCCC
GTATCGACGAAACTTCTGAATATATCGGCACGCTCAAGTCCCGGCAATCGGTGGTGCTGCGCCCGCAGATCGAGGGGCGG
ATAAGCCGGATTTTTGTGCGCTCCGGCAGCAATGTGGCGGCGCAAGCCCCGCTTATCGAAGTCGATCCCGACCGGCAGCG
GGCGGTTACCGAGAGTTCGCGCTCAGCGGCGCGCTCCGCCCAGGCGGAACTAGACAACACCAGCGCCCTAGTCAGGTCTT
ACGCGGCCCGCCGGGAGGCTGGCCAGGCAAACTTCAAATTTATTCGGCAGCAACGTGATCGGTACGCCCGCCTGCGCGCC
GAAGGGGCGATCAGCCAGGAAAATCTTGACGAGTACGACAACCGCCTGGCGGCGGCCCGGGCGGAACTCGAAGCTGCCGA
AGCCCAATTGGCGGCTCAGCGCTCCGCGGTCGAGCGTGCCCGGCGCGGCCTCGATCAAGCGCGCGCGCAAGCCCGCGAAC
AGCAAGTGCAGCTGCAGTACTACCGGGTGAGCGCTCCTTTCGAAGGTCGCATCGGCGATATTCCCGCCCGGGTAGGCGAT
TACATCACTCCCGCCACGGAACTGACGACCATCACCCAAAACCGTCCGCTCGAAATCTATGTCCCGGTCCCGCTTGAGCG
CGTCTCGGAGCTGTATCCGGGCATGCAGCTGCAGCTTTTCGACGACCAGGATCGCTCCTTGGGGGCGAGCAAAGTCGGGT
ACATCGCCCCGCGCGTGGACGATCAAACCCAGTCGGTGCTGGTCAAAGCCTGGGTCGACAACGCCGCGGGCCGGATGCGC
TCCGACCAGTTTGTGCGGGTCCGGCTGGTCTGGAAATCTCGCCAAGCGGTGTCGGTCCCGACTGCGGCCGTCACCCAAAT
CAGCGGCCAGAACTTTGTCTTTGTCGCCCAGGCGAACGGGCGTTCCGGGCTTGTCGCACGGCAGAAGGCGGTCACCCTCG
CCGAGGTCGAAGGCAAGCGCTATCCGGTCCTCGCGGGACTGCGGCCCGGGGAAAAGATCGTCGTCTCGGGCATTCAGAAG
CTCTCGGACGGCGCACCCATCTCCGCGCTCTAG

Upstream 100 bases:

>100_bases
TGCCCTGGAGCAGGTCGCTCCCCGCGGCGTCGCGGCTGGAGCGCGCTATCCCGAAGCATTGCTGCAGATCACCCGTTGAG
ATGTACTGCCCGAGGAGGGT

Downstream 100 bases:

>100_bases
AAGCCAGACGCACACGCACCCAGGGATACCGAACCGATGTTCGTCAATTATTTTGTCCAACGGCCTATCCTCACCATCGC
CTGCTCGGTAATCATCGTGC

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MMSARPFDNLIVPKLLLAALAASGIQACGSARSATETEKPAATPVALATVRSSRIDETSEYIGTLKSRQSVVLRPQIEGR
ISRIFVRSGSNVAAQAPLIEVDPDRQRAVTESSRSAARSAQAELDNTSALVRSYAARREAGQANFKFIRQQRDRYARLRA
EGAISQENLDEYDNRLAAARAELEAAEAQLAAQRSAVERARRGLDQARAQAREQQVQLQYYRVSAPFEGRIGDIPARVGD
YITPATELTTITQNRPLEIYVPVPLERVSELYPGMQLQLFDDQDRSLGASKVGYIAPRVDDQTQSVLVKAWVDNAAGRMR
SDQFVRVRLVWKSRQAVSVPTAAVTQISGQNFVFVAQANGRSGLVARQKAVTLAEVEGKRYPVLAGLRPGEKIVVSGIQK
LSDGAPISAL

Sequences:

>Translated_410_residues
MMSARPFDNLIVPKLLLAALAASGIQACGSARSATETEKPAATPVALATVRSSRIDETSEYIGTLKSRQSVVLRPQIEGR
ISRIFVRSGSNVAAQAPLIEVDPDRQRAVTESSRSAARSAQAELDNTSALVRSYAARREAGQANFKFIRQQRDRYARLRA
EGAISQENLDEYDNRLAAARAELEAAEAQLAAQRSAVERARRGLDQARAQAREQQVQLQYYRVSAPFEGRIGDIPARVGD
YITPATELTTITQNRPLEIYVPVPLERVSELYPGMQLQLFDDQDRSLGASKVGYIAPRVDDQTQSVLVKAWVDNAAGRMR
SDQFVRVRLVWKSRQAVSVPTAAVTQISGQNFVFVAQANGRSGLVARQKAVTLAEVEGKRYPVLAGLRPGEKIVVSGIQK
LSDGAPISAL
>Mature_410_residues
MMSARPFDNLIVPKLLLAALAASGIQACGSARSATETEKPAATPVALATVRSSRIDETSEYIGTLKSRQSVVLRPQIEGR
ISRIFVRSGSNVAAQAPLIEVDPDRQRAVTESSRSAARSAQAELDNTSALVRSYAARREAGQANFKFIRQQRDRYARLRA
EGAISQENLDEYDNRLAAARAELEAAEAQLAAQRSAVERARRGLDQARAQAREQQVQLQYYRVSAPFEGRIGDIPARVGD
YITPATELTTITQNRPLEIYVPVPLERVSELYPGMQLQLFDDQDRSLGASKVGYIAPRVDDQTQSVLVKAWVDNAAGRMR
SDQFVRVRLVWKSRQAVSVPTAAVTQISGQNFVFVAQANGRSGLVARQKAVTLAEVEGKRYPVLAGLRPGEKIVVSGIQK
LSDGAPISAL

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=374, Percent_Identity=22.9946524064171, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789929, Length=420, Percent_Identity=25.952380952381, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786668, Length=433, Percent_Identity=26.5588914549654, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44756; Mature: 44756

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSARPFDNLIVPKLLLAALAASGIQACGSARSATETEKPAATPVALATVRSSRIDETSE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHH
YIGTLKSRQSVVLRPQIEGRISRIFVRSGSNVAAQAPLIEVDPDRQRAVTESSRSAARSA
HHHHHHCCCCEEECCCHHCCEEEEEEECCCCCEECCCEEEECCCHHHHHHHHHHHHHHHH
QAELDNTSALVRSYAARREAGQANFKFIRQQRDRYARLRAEGAISQENLDEYDNRLAAAR
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AELEAAEAQLAAQRSAVERARRGLDQARAQAREQQVQLQYYRVSAPFEGRIGDIPARVGD
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCHHHCC
YITPATELTTITQNRPLEIYVPVPLERVSELYPGMQLQLFDDQDRSLGASKVGYIAPRVD
CCCCCHHEEEEECCCCEEEEECCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCEECCCCC
DQTQSVLVKAWVDNAAGRMRSDQFVRVRLVWKSRQAVSVPTAAVTQISGQNFVFVAQANG
CHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHHHEECCCCEEEEEECCC
RSGLVARQKAVTLAEVEGKRYPVLAGLRPGEKIVVSGIQKLSDGAPISAL
CCCCEEHHHHHEEEECCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MMSARPFDNLIVPKLLLAALAASGIQACGSARSATETEKPAATPVALATVRSSRIDETSE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHH
YIGTLKSRQSVVLRPQIEGRISRIFVRSGSNVAAQAPLIEVDPDRQRAVTESSRSAARSA
HHHHHHCCCCEEECCCHHCCEEEEEEECCCCCEECCCEEEECCCHHHHHHHHHHHHHHHH
QAELDNTSALVRSYAARREAGQANFKFIRQQRDRYARLRAEGAISQENLDEYDNRLAAAR
HHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
AELEAAEAQLAAQRSAVERARRGLDQARAQAREQQVQLQYYRVSAPFEGRIGDIPARVGD
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCHHHCC
YITPATELTTITQNRPLEIYVPVPLERVSELYPGMQLQLFDDQDRSLGASKVGYIAPRVD
CCCCCHHEEEEECCCCEEEEECCCHHHHHHHCCCCEEEEECCCCCCCCCCCCCEECCCCC
DQTQSVLVKAWVDNAAGRMRSDQFVRVRLVWKSRQAVSVPTAAVTQISGQNFVFVAQANG
CHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCHHHHHEECCCCEEEEEECCC
RSGLVARQKAVTLAEVEGKRYPVLAGLRPGEKIVVSGIQKLSDGAPISAL
CCCCEEHHHHHEEEECCCCCCCEEECCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]