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The map label for this gene is galE [H]

Identifier: 37522389

GI number: 37522389

Start: 2997833

End: 2998837

Strand: Direct

Name: galE [H]

Synonym: glr2820

Alternate gene names: 37522389

Gene position: 2997833-2998837 (Clockwise)

Preceding gene: 37522386

Following gene: 37522390

Centisome position: 64.34

GC content: 64.68

Gene sequence:

>1005_bases
GTGTGGAGCTGCACGACGAGGCAAAGCGCGATGATTTTGGTGACAGGCGGCGCCGGCTACATCGGCTCCCACGTGGTTCT
TGCTCTGCAGGCCGCGGGCTTCGAGATACTGGTGTACGACAACCTGGTTTACGGCCATGCCGAGTTTGTTCCGGCCCCGA
TGCTGATTCGCGGCGACCTTGAAGATCGCGTGGGGCTCGCGCGCCTGTTTGCCGCGCATCCGATCGAGGCGGTCATCCAC
ATGGCGGCTTACGCCTACGTGGGCGAATCGGTCACCAAACCCGCCGTCTACTACCGCAACAACGTCCACGGCACGCTCTG
CCTGCTGGAGGCGATGGTCGAAGCCGACGTCAAGCAAATCGTCTTCTCCTCTACCTGCGCCACCTACGGCGAACCCGAAC
AGATCCCGATCACCGAAACCCATCCCCAGCGCCCCATCAATCCCTACGGATTCACCAAGCTGGTGGTCGAGCGGATGCTG
CGCGACTTCGACCGCGCCTACGGCCTGAGATCGGTTGTTTTTCGCTACTTCAACGCCGCGGGCGCCGACCCGGACGCCCG
GGTCGGCGAAGACCACGACCCTGAGACCCACATCATTCCGCTGGTGCTCGATGTCGCCATCGGCCGTCGGCCCCACATCA
CCGTCTTCGGCTCCGACTACGAAACCCCCGACGGCACCTGCGTGCGCGACTACATCCATGTCAGCGACCTGGCCGACGCC
CATGTGCTGGGGCTCAAGTACCTCAAATCCGGCGGCCCGACCGAGGTATTCAACCTGGGCAACGGCAGCGGCTTTTCGGT
GCAACAGGTGATCGACACGGCCGGACAAGTCGCCGGACGTGAGATCGCCGTGCAGATGGGTGCGCGCCGCCCCGGCGACC
CGGCGACGCTGGTGGGTTCCGCAGAGCGCGCCCGCGCAATTCTGGGCTGGCAGCCGCGCTTTGCGGATTTGCAGACCATC
GTCAGCACCGCCTGGACCTGGCACCAGAAACGCTTCGGCGGCTAA

Upstream 100 bases:

>100_bases
TCAATTTAGGCATGGCTCTACGCTCTCCAATTTCTATTCTTGCCCAATCCAGTCAAACAACTAGGGCACTATGCAGACAT
CTCCCCCGGGGCCGATACTG

Downstream 100 bases:

>100_bases
ATTGCAGCGAGTAAGCCGGCAATGTTAGGCTGGTTTCTCGCGGGGAGTTAGCTCAGTTGGTAGAGCGCAGCAATCGCACT
GCTGAGGTCAGGGGTTCGAA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MWSCTTRQSAMILVTGGAGYIGSHVVLALQAAGFEILVYDNLVYGHAEFVPAPMLIRGDLEDRVGLARLFAAHPIEAVIH
MAAYAYVGESVTKPAVYYRNNVHGTLCLLEAMVEADVKQIVFSSTCATYGEPEQIPITETHPQRPINPYGFTKLVVERML
RDFDRAYGLRSVVFRYFNAAGADPDARVGEDHDPETHIIPLVLDVAIGRRPHITVFGSDYETPDGTCVRDYIHVSDLADA
HVLGLKYLKSGGPTEVFNLGNGSGFSVQQVIDTAGQVAGREIAVQMGARRPGDPATLVGSAERARAILGWQPRFADLQTI
VSTAWTWHQKRFGG

Sequences:

>Translated_334_residues
MWSCTTRQSAMILVTGGAGYIGSHVVLALQAAGFEILVYDNLVYGHAEFVPAPMLIRGDLEDRVGLARLFAAHPIEAVIH
MAAYAYVGESVTKPAVYYRNNVHGTLCLLEAMVEADVKQIVFSSTCATYGEPEQIPITETHPQRPINPYGFTKLVVERML
RDFDRAYGLRSVVFRYFNAAGADPDARVGEDHDPETHIIPLVLDVAIGRRPHITVFGSDYETPDGTCVRDYIHVSDLADA
HVLGLKYLKSGGPTEVFNLGNGSGFSVQQVIDTAGQVAGREIAVQMGARRPGDPATLVGSAERARAILGWQPRFADLQTI
VSTAWTWHQKRFGG
>Mature_334_residues
MWSCTTRQSAMILVTGGAGYIGSHVVLALQAAGFEILVYDNLVYGHAEFVPAPMLIRGDLEDRVGLARLFAAHPIEAVIH
MAAYAYVGESVTKPAVYYRNNVHGTLCLLEAMVEADVKQIVFSSTCATYGEPEQIPITETHPQRPINPYGFTKLVVERML
RDFDRAYGLRSVVFRYFNAAGADPDARVGEDHDPETHIIPLVLDVAIGRRPHITVFGSDYETPDGTCVRDYIHVSDLADA
HVLGLKYLKSGGPTEVFNLGNGSGFSVQQVIDTAGQVAGREIAVQMGARRPGDPATLVGSAERARAILGWQPRFADLQTI
VSTAWTWHQKRFGG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=40.5882352941176, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=40.5882352941176, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=40.5882352941176, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI7657641, Length=337, Percent_Identity=26.7062314540059, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI42516563, Length=320, Percent_Identity=25.3125, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=38.0952380952381, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI1788353, Length=337, Percent_Identity=29.3768545994065, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI48994969, Length=334, Percent_Identity=27.8443113772455, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1790049, Length=267, Percent_Identity=30.3370786516854, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788365, Length=298, Percent_Identity=25.503355704698, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71982035, Length=340, Percent_Identity=39.4117647058824, Blast_Score=234, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI71982038, Length=342, Percent_Identity=39.1812865497076, Blast_Score=233, Evalue=9e-62,
Organism=Caenorhabditis elegans, GI17568069, Length=328, Percent_Identity=25, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI115532424, Length=349, Percent_Identity=26.0744985673352, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI133901786, Length=346, Percent_Identity=24.2774566473988, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI133901790, Length=346, Percent_Identity=24.2774566473988, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI133901788, Length=346, Percent_Identity=24.2774566473988, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17539422, Length=346, Percent_Identity=24.2774566473988, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17539424, Length=346, Percent_Identity=24.2774566473988, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17507723, Length=349, Percent_Identity=23.7822349570201, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=340, Percent_Identity=37.9411764705882, Blast_Score=224, Evalue=1e-59,
Organism=Drosophila melanogaster, GI19923002, Length=342, Percent_Identity=38.8888888888889, Blast_Score=235, Evalue=3e-62,
Organism=Drosophila melanogaster, GI21356223, Length=318, Percent_Identity=26.1006289308176, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36485; Mature: 36485

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSCTTRQSAMILVTGGAGYIGSHVVLALQAAGFEILVYDNLVYGHAEFVPAPMLIRGDL
CCCCCCCCCEEEEEECCCCHHHHHHHEEEECCCEEEEEECCEEECCHHHCCCCEEEECCC
EDRVGLARLFAAHPIEAVIHMAAYAYVGESVTKPAVYYRNNVHGTLCLLEAMVEADVKQI
HHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
VFSSTCATYGEPEQIPITETHPQRPINPYGFTKLVVERMLRDFDRAYGLRSVVFRYFNAA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GADPDARVGEDHDPETHIIPLVLDVAIGRRPHITVFGSDYETPDGTCVRDYIHVSDLADA
CCCCCCCCCCCCCCCCEEHHHHEEHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCHH
HVLGLKYLKSGGPTEVFNLGNGSGFSVQQVIDTAGQVAGREIAVQMGARRPGDPATLVGS
HHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCHHHEEEECCCCCCCCCEEECC
AERARAILGWQPRFADLQTIVSTAWTWHQKRFGG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWSCTTRQSAMILVTGGAGYIGSHVVLALQAAGFEILVYDNLVYGHAEFVPAPMLIRGDL
CCCCCCCCCEEEEEECCCCHHHHHHHEEEECCCEEEEEECCEEECCHHHCCCCEEEECCC
EDRVGLARLFAAHPIEAVIHMAAYAYVGESVTKPAVYYRNNVHGTLCLLEAMVEADVKQI
HHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
VFSSTCATYGEPEQIPITETHPQRPINPYGFTKLVVERMLRDFDRAYGLRSVVFRYFNAA
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GADPDARVGEDHDPETHIIPLVLDVAIGRRPHITVFGSDYETPDGTCVRDYIHVSDLADA
CCCCCCCCCCCCCCCCEEHHHHEEHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCHH
HVLGLKYLKSGGPTEVFNLGNGSGFSVQQVIDTAGQVAGREIAVQMGARRPGDPATLVGS
HHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCHHHEEEECCCCCCCCCEEECC
AERARAILGWQPRFADLQTIVSTAWTWHQKRFGG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]