Click here to switch to the map view.

The map label for this gene is pknD [H]

Identifier: 37522270

GI number: 37522270

Start: 2860608

End: 2861663

Strand: Reverse

Name: pknD [H]

Synonym: gll2701

Alternate gene names: 37522270

Gene position: 2861663-2860608 (Counterclockwise)

Preceding gene: 37522273

Following gene: 37522268

Centisome position: 61.42

GC content: 68.28

Gene sequence:

>1056_bases
ATGCAAGAAAAGTCTCGGCGGTTTGACTCCCGATGGGTGTGGTTTGCGCTGTTGGGGACGGCGCTGGGAAGTTTTGCGCT
GCGCAGCGTCGTGGCCGGAAACCACATCAAAGTCGCAGAGGAGCCTTTGTACCCGGTCTTTGTGCTGCCTGCCCCCGCGG
GTGAACTCTTTGTCGTCGAGCACAGCCGCAACCAGATTCTCAAACTCGTCCCTGGACGCTTACCTACGGTGATTGCCGGC
AACGGCACAAGCGACTACTCGGGCGACGGCGGTCCGGCGACCCGCGCGGGGCTTTTTATGATGGGCATCGCCCGCGACCG
GGCGGGCAACCTCTACATCGCCGATCACAACCACCACCGCGTCCGTCGCGTCGGTACGGACGGGCGCATCGAGACGATCG
CGGGCACCGGCGAGGCCGACTACGGCGGCGACGGCGGCCCGGCAAAGCAGGCCAGATTCAACGATCCGGCCGGGGTGGCG
GTGGACGCCCTGGGCAACGTGCTGGTGGCCGATACTTATAACCACCGCATCCGGACGATTGGGCCGGACGGGACGATTCG
CACGGTGGCGGGCACCGGGCAAGCGGGCTACAGCGGTGACGGCGGCCCGGCGACGGCGGCCCGGCTCGATTTTCCCTGGG
GGGTCGCCGTGGCGCCCGACGGACGGATACTGATCGCCGATACCGGCAACAACCGGATCCGCTCCATCGGGCCGGACGGG
ACGATTCGCACGGTGGCGGGCACCGGGCAGGCCGGTTTCGGGGGCGACGGCGGCCCGGCGGTGAAGGCCCGCTTGGAGCG
GCCCCAACTGGCCGTAGCCGACCACCGGGGCAATCTCTTTGTGGCCGACACCAACAACAACCGCGTGCGCCGGATCGCAC
CGGACGGCACGATCTCGACGGTGGCCGGGGGCGAGCCGCCCGCCGCCGCCCGCTTGAACGACCCGTTCGCCGTCGGTGTG
GACGAGCGGGGCCATCTGTACATCGCCGACACCGGCAACTTCCGCGTGCTCAAAATCGACGGTAGCGGCCGTACCGAGAC
GCTCACCCTGAAGTGA

Upstream 100 bases:

>100_bases
CAGCGGATTGCCCGCGACGAACTTGCTCAGCACAACGAGGCTCCGGAGGGTTTACCCTGGTTCAGGCTAGGGTGCAAGTG
ACCTGAACGAATAATACGCG

Downstream 100 bases:

>100_bases
GCGCCCTAGAGATACTGGGCCAGCACCTGGTGGAAGTGAGCGACTCCCAGTTCGTGCTCACCTGCCAGGGCGCGCACCTG
ATAGGCCCGCGAGCCGATTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MQEKSRRFDSRWVWFALLGTALGSFALRSVVAGNHIKVAEEPLYPVFVLPAPAGELFVVEHSRNQILKLVPGRLPTVIAG
NGTSDYSGDGGPATRAGLFMMGIARDRAGNLYIADHNHHRVRRVGTDGRIETIAGTGEADYGGDGGPAKQARFNDPAGVA
VDALGNVLVADTYNHRIRTIGPDGTIRTVAGTGQAGYSGDGGPATAARLDFPWGVAVAPDGRILIADTGNNRIRSIGPDG
TIRTVAGTGQAGFGGDGGPAVKARLERPQLAVADHRGNLFVADTNNNRVRRIAPDGTISTVAGGEPPAAARLNDPFAVGV
DERGHLYIADTGNFRVLKIDGSGRTETLTLK

Sequences:

>Translated_351_residues
MQEKSRRFDSRWVWFALLGTALGSFALRSVVAGNHIKVAEEPLYPVFVLPAPAGELFVVEHSRNQILKLVPGRLPTVIAG
NGTSDYSGDGGPATRAGLFMMGIARDRAGNLYIADHNHHRVRRVGTDGRIETIAGTGEADYGGDGGPAKQARFNDPAGVA
VDALGNVLVADTYNHRIRTIGPDGTIRTVAGTGQAGYSGDGGPATAARLDFPWGVAVAPDGRILIADTGNNRIRSIGPDG
TIRTVAGTGQAGFGGDGGPAVKARLERPQLAVADHRGNLFVADTNNNRVRRIAPDGTISTVAGGEPPAAARLNDPFAVGV
DERGHLYIADTGNFRVLKIDGSGRTETLTLK
>Mature_351_residues
MQEKSRRFDSRWVWFALLGTALGSFALRSVVAGNHIKVAEEPLYPVFVLPAPAGELFVVEHSRNQILKLVPGRLPTVIAG
NGTSDYSGDGGPATRAGLFMMGIARDRAGNLYIADHNHHRVRRVGTDGRIETIAGTGEADYGGDGGPAKQARFNDPAGVA
VDALGNVLVADTYNHRIRTIGPDGTIRTVAGTGQAGYSGDGGPATAARLDFPWGVAVAPDGRILIADTGNNRIRSIGPDG
TIRTVAGTGQAGFGGDGGPAVKARLERPQLAVADHRGNLFVADTNNNRVRRIAPDGTISTVAGGEPPAAARLNDPFAVGV
DERGHLYIADTGNFRVLKIDGSGRTETLTLK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI84993742, Length=309, Percent_Identity=29.126213592233, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI110347400, Length=373, Percent_Identity=26.8096514745308, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI253970446, Length=373, Percent_Identity=26.5415549597855, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI253970444, Length=373, Percent_Identity=26.5415549597855, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI169790825, Length=370, Percent_Identity=27.5675675675676, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI170016091, Length=369, Percent_Identity=28.1842818428184, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI42476013, Length=278, Percent_Identity=29.8561151079137, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI122937400, Length=343, Percent_Identity=28.2798833819242, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI32454739, Length=244, Percent_Identity=26.2295081967213, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI32454737, Length=244, Percent_Identity=26.2295081967213, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI194248081, Length=248, Percent_Identity=26.6129032258064, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI194248079, Length=248, Percent_Identity=26.6129032258064, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71980713, Length=236, Percent_Identity=27.9661016949153, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71980716, Length=236, Percent_Identity=27.9661016949153, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17553622, Length=245, Percent_Identity=29.3877551020408, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221330419, Length=257, Percent_Identity=29.9610894941634, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655386, Length=257, Percent_Identity=29.9610894941634, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI22024206, Length=257, Percent_Identity=29.9610894941634, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI221330033, Length=238, Percent_Identity=25.2100840336134, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI221330031, Length=238, Percent_Identity=25.2100840336134, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24586266, Length=238, Percent_Identity=25.2100840336134, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24586264, Length=238, Percent_Identity=25.2100840336134, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI22026822, Length=238, Percent_Identity=25.2100840336134, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24668551, Length=279, Percent_Identity=27.5985663082437, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI161085696, Length=279, Percent_Identity=27.5985663082437, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI281360749, Length=275, Percent_Identity=29.8181818181818, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221329864, Length=275, Percent_Identity=29.8181818181818, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24641507, Length=275, Percent_Identity=29.8181818181818, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281360755, Length=275, Percent_Identity=29.8181818181818, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281360753, Length=275, Percent_Identity=29.8181818181818, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281360751, Length=275, Percent_Identity=29.8181818181818, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI221329862, Length=275, Percent_Identity=29.8181818181818, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR011009
- InterPro:   IPR001258
- InterPro:   IPR013017
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271 [H]

Pfam domain/function: PF01436 NHL; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 36755; Mature: 36755

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS51125 NHL L=RR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEKSRRFDSRWVWFALLGTALGSFALRSVVAGNHIKVAEEPLYPVFVLPAPAGELFVVE
CCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCEEEEE
HSRNQILKLVPGRLPTVIAGNGTSDYSGDGGPATRAGLFMMGIARDRAGNLYIADHNHHR
CCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCHHHCEEEEEEEECCCCEEEEEECCCCE
VRRVGTDGRIETIAGTGEADYGGDGGPAKQARFNDPAGVAVDALGNVLVADTYNHRIRTI
EEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEHHHCCCEEEEECCCCEEEEE
GPDGTIRTVAGTGQAGYSGDGGPATAARLDFPWGVAVAPDGRILIADTGNNRIRSIGPDG
CCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCEEECCCCEEEEEECCCCEEEEECCCC
TIRTVAGTGQAGFGGDGGPAVKARLERPQLAVADHRGNLFVADTNNNRVRRIAPDGTIST
CEEEEECCCCCCCCCCCCCCEEEECCCCCEEEEECCCCEEEEECCCCEEEEECCCCCEEE
VAGGEPPAAARLNDPFAVGVDERGHLYIADTGNFRVLKIDGSGRTETLTLK
ECCCCCCCCCCCCCCEEEECCCCCCEEEEECCCEEEEEECCCCCEEEEEEC
>Mature Secondary Structure
MQEKSRRFDSRWVWFALLGTALGSFALRSVVAGNHIKVAEEPLYPVFVLPAPAGELFVVE
CCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCEEEEE
HSRNQILKLVPGRLPTVIAGNGTSDYSGDGGPATRAGLFMMGIARDRAGNLYIADHNHHR
CCCCCEEEECCCCCCEEEECCCCCCCCCCCCCCHHHCEEEEEEEECCCCEEEEEECCCCE
VRRVGTDGRIETIAGTGEADYGGDGGPAKQARFNDPAGVAVDALGNVLVADTYNHRIRTI
EEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEHHHCCCEEEEECCCCEEEEE
GPDGTIRTVAGTGQAGYSGDGGPATAARLDFPWGVAVAPDGRILIADTGNNRIRSIGPDG
CCCCCEEEEEECCCCCCCCCCCCCEEEEECCCCCEEECCCCEEEEEECCCCEEEEECCCC
TIRTVAGTGQAGFGGDGGPAVKARLERPQLAVADHRGNLFVADTNNNRVRRIAPDGTIST
CEEEEECCCCCCCCCCCCCCEEEECCCCCEEEEECCCCEEEEECCCCEEEEECCCCCEEE
VAGGEPPAAARLNDPFAVGVDERGHLYIADTGNFRVLKIDGSGRTETLTLK
ECCCCCCCCCCCCCCEEEECCCCCCEEEEECCCEEEEEECCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9119030; 9634230; 12218036 [H]