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The map label for this gene is aspC [H]

Identifier: 37522169

GI number: 37522169

Start: 2756049

End: 2757236

Strand: Direct

Name: aspC [H]

Synonym: glr2600

Alternate gene names: 37522169

Gene position: 2756049-2757236 (Clockwise)

Preceding gene: 37522168

Following gene: 37522171

Centisome position: 59.16

GC content: 66.41

Gene sequence:

>1188_bases
ATGTCCCGCCTGGCCACCCGCGTCGCTTCGCTGACTCCATCGCTCACGCTTGCCATTGCCGCCAAAGCCAAGGCGCTGGC
GGCGGGCGGCGTCGATGTGTGCGGCCTGAGCGCCGGGGAACCCGATTTCGATACTCCTGCTCCCATCAAGGCGGCGGCCA
AGGCGGCCCTCGACCGCGGTGAGACCAAGTACGGACCGGTGGCCGGGCAGCCGCGCCTGCGCGAACGGATTGCCCGAAAG
TTGGAGCGCGAAAACGGCCTACCCTACACCCCCGAGCAGATTCTGGTCACCAACGGCGGCAAGCAGGGCCTTTACAACGC
GATCATGGCCCTCATCGAACCCGGCGATGCGGTGCTCATCCCGAGCCCCTACTGGCTGAGCTACCCGGAGATGGTTTCGC
TCGCGGGCGGTACCTCGGTGCTCTTGCCCACCACCGAGGCGACCGGCTTCAAGATCACGCCTGAGCAACTGGAGGCCGCC
ATCACCCCCCGCACCCGGTTGCTCATCCTCAATTCCCCCTCCAACCCGACGGGCATGGTCTACAGCCGCCCCGAACTGGA
GGCGATTACCGAGGTGGTTCTGCGCCACGACCTGATGGTTCTCTCCGACGAAATCTACGAAAAACTCGTCTACGACGGCG
CGCGGCACCACAGCATCGGCGGCCTGGGGCGCGAAATGTTTGCGCGCACGATCACCAGCGGCGGCTTCAGCAAGGCTTTT
GCGATGACCGGCTGGCGGCTCGGGTACCTGGCCGGTCCCACGGACCTGATTGGGGCCGCCGGCGCCATTCAGAGCCACAG
CACCTCCAACGTCGCCGCCTACTCCCAAGCCGGGGCGTTGGCGGCCCTCGAAGATCCGCAGGTGGCGCTCGAAGTGGAGC
GGATGGTGCGCGTCTTCGCCGAGCGGCGCACCGCCATGTACGATGCGGTGGCGGCGATCCCGGGTCTGCGCTGTGCCCGT
GCCCAGGGGGCTTTCTATCTGCTGCCGGATATTTCCGCCACGGGCCTCAATTCCACGGCCTTCTGCGAACAACTGCTCGA
CCAATTCCACGTCGCTGCGGTGCCCGGCATCGCCTTCGGCTCGGACAGCCACGTCCGCCTTTCTTACGCCACCGACCTCG
ACACCATCTACAAAGGCGTTGAACGTCTCGGCCAGTTTGTGCGCCAGTGCCTGGCCGTGCGCGCCTGA

Upstream 100 bases:

>100_bases
CGGCTCCGATCGCCGTCGCTTCGATCCCACCGCCCACGGTTGTGTGTCAAGCTGGGAAAACGGCCAATTTGTGCCAATCG
TTATCTGGAGAACTTTCGCC

Downstream 100 bases:

>100_bases
AGCACTCTACAAGATGCTCTCCAGCCCCACGATGAGCCGGTCGATCTCTGCAGGCGTGTTGTAGTGGACCATCGAGACGC
GCACGATCCCCCCGGCAGGG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSRLATRVASLTPSLTLAIAAKAKALAAGGVDVCGLSAGEPDFDTPAPIKAAAKAALDRGETKYGPVAGQPRLRERIARK
LERENGLPYTPEQILVTNGGKQGLYNAIMALIEPGDAVLIPSPYWLSYPEMVSLAGGTSVLLPTTEATGFKITPEQLEAA
ITPRTRLLILNSPSNPTGMVYSRPELEAITEVVLRHDLMVLSDEIYEKLVYDGARHHSIGGLGREMFARTITSGGFSKAF
AMTGWRLGYLAGPTDLIGAAGAIQSHSTSNVAAYSQAGALAALEDPQVALEVERMVRVFAERRTAMYDAVAAIPGLRCAR
AQGAFYLLPDISATGLNSTAFCEQLLDQFHVAAVPGIAFGSDSHVRLSYATDLDTIYKGVERLGQFVRQCLAVRA

Sequences:

>Translated_395_residues
MSRLATRVASLTPSLTLAIAAKAKALAAGGVDVCGLSAGEPDFDTPAPIKAAAKAALDRGETKYGPVAGQPRLRERIARK
LERENGLPYTPEQILVTNGGKQGLYNAIMALIEPGDAVLIPSPYWLSYPEMVSLAGGTSVLLPTTEATGFKITPEQLEAA
ITPRTRLLILNSPSNPTGMVYSRPELEAITEVVLRHDLMVLSDEIYEKLVYDGARHHSIGGLGREMFARTITSGGFSKAF
AMTGWRLGYLAGPTDLIGAAGAIQSHSTSNVAAYSQAGALAALEDPQVALEVERMVRVFAERRTAMYDAVAAIPGLRCAR
AQGAFYLLPDISATGLNSTAFCEQLLDQFHVAAVPGIAFGSDSHVRLSYATDLDTIYKGVERLGQFVRQCLAVRA
>Mature_394_residues
SRLATRVASLTPSLTLAIAAKAKALAAGGVDVCGLSAGEPDFDTPAPIKAAAKAALDRGETKYGPVAGQPRLRERIARKL
ERENGLPYTPEQILVTNGGKQGLYNAIMALIEPGDAVLIPSPYWLSYPEMVSLAGGTSVLLPTTEATGFKITPEQLEAAI
TPRTRLLILNSPSNPTGMVYSRPELEAITEVVLRHDLMVLSDEIYEKLVYDGARHHSIGGLGREMFARTITSGGFSKAFA
MTGWRLGYLAGPTDLIGAAGAIQSHSTSNVAAYSQAGALAALEDPQVALEVERMVRVFAERRTAMYDAVAAIPGLRCARA
QGAFYLLPDISATGLNSTAFCEQLLDQFHVAAVPGIAFGSDSHVRLSYATDLDTIYKGVERLGQFVRQCLAVRA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=325, Percent_Identity=31.0769230769231, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI95147551, Length=392, Percent_Identity=27.8061224489796, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI169881279, Length=392, Percent_Identity=27.8061224489796, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI56713256, Length=325, Percent_Identity=31.0769230769231, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI169881281, Length=303, Percent_Identity=26.4026402640264, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI4507369, Length=386, Percent_Identity=26.1658031088083, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI19263340, Length=356, Percent_Identity=23.0337078651685, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI215599424, Length=365, Percent_Identity=23.013698630137, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI187936925, Length=238, Percent_Identity=32.7731092436975, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI14211921, Length=238, Percent_Identity=32.7731092436975, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI149944424, Length=241, Percent_Identity=29.045643153527, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4885351, Length=347, Percent_Identity=23.9193083573487, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI7705897, Length=363, Percent_Identity=23.9669421487603, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI33469970, Length=363, Percent_Identity=23.9669421487603, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=30.3108808290155, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788627, Length=386, Percent_Identity=30.0518134715026, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788722, Length=401, Percent_Identity=29.1770573566085, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790797, Length=303, Percent_Identity=27.0627062706271, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787909, Length=296, Percent_Identity=26.3513513513513, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994472, Length=290, Percent_Identity=32.0689655172414, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI71994476, Length=290, Percent_Identity=32.0689655172414, Blast_Score=130, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17567369, Length=330, Percent_Identity=28.7878787878788, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17567663, Length=340, Percent_Identity=26.7647058823529, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71981209, Length=372, Percent_Identity=23.9247311827957, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71981215, Length=174, Percent_Identity=25.2873563218391, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=392, Percent_Identity=26.2755102040816, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320317, Length=355, Percent_Identity=24.7887323943662, Blast_Score=90, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323118, Length=378, Percent_Identity=23.8095238095238, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28573069, Length=326, Percent_Identity=29.1411042944785, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24646114, Length=326, Percent_Identity=29.1411042944785, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28573067, Length=326, Percent_Identity=29.1411042944785, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28573065, Length=326, Percent_Identity=29.1411042944785, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI18859735, Length=313, Percent_Identity=24.6006389776358, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24641770, Length=395, Percent_Identity=25.8227848101266, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641760, Length=395, Percent_Identity=25.8227848101266, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641768, Length=395, Percent_Identity=25.8227848101266, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641766, Length=395, Percent_Identity=25.8227848101266, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641764, Length=395, Percent_Identity=25.8227848101266, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45551451, Length=395, Percent_Identity=25.8227848101266, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42050; Mature: 41919

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLATRVASLTPSLTLAIAAKAKALAAGGVDVCGLSAGEPDFDTPAPIKAAAKAALDRG
CCHHHHHHHHCCCCEEEEEEHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHCC
ETKYGPVAGQPRLRERIARKLERENGLPYTPEQILVTNGGKQGLYNAIMALIEPGDAVLI
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEE
PSPYWLSYPEMVSLAGGTSVLLPTTEATGFKITPEQLEAAITPRTRLLILNSPSNPTGMV
CCCCCCCCHHHHHHCCCCEEEEECCCCCCCEECHHHHHHHCCCCEEEEEEECCCCCCCEE
YSRPELEAITEVVLRHDLMVLSDEIYEKLVYDGARHHSIGGLGREMFARTITSGGFSKAF
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHH
AMTGWRLGYLAGPTDLIGAAGAIQSHSTSNVAAYSQAGALAALEDPQVALEVERMVRVFA
HHCCEEEEEECCCHHHHHCCCCCCCCCCCCEEHHHHCCCEEECCCCHHHHHHHHHHHHHH
ERRTAMYDAVAAIPGLRCARAQGAFYLLPDISATGLNSTAFCEQLLDQFHVAAVPGIAFG
HHHHHHHHHHHHCCCCHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEC
SDSHVRLSYATDLDTIYKGVERLGQFVRQCLAVRA
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRLATRVASLTPSLTLAIAAKAKALAAGGVDVCGLSAGEPDFDTPAPIKAAAKAALDRG
CHHHHHHHHCCCCEEEEEEHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHCC
ETKYGPVAGQPRLRERIARKLERENGLPYTPEQILVTNGGKQGLYNAIMALIEPGDAVLI
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEE
PSPYWLSYPEMVSLAGGTSVLLPTTEATGFKITPEQLEAAITPRTRLLILNSPSNPTGMV
CCCCCCCCHHHHHHCCCCEEEEECCCCCCCEECHHHHHHHCCCCEEEEEEECCCCCCCEE
YSRPELEAITEVVLRHDLMVLSDEIYEKLVYDGARHHSIGGLGREMFARTITSGGFSKAF
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHHHH
AMTGWRLGYLAGPTDLIGAAGAIQSHSTSNVAAYSQAGALAALEDPQVALEVERMVRVFA
HHCCEEEEEECCCHHHHHCCCCCCCCCCCCEEHHHHCCCEEECCCCHHHHHHHHHHHHHH
ERRTAMYDAVAAIPGLRCARAQGAFYLLPDISATGLNSTAFCEQLLDQFHVAAVPGIAFG
HHHHHHHHHHHHCCCCHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEC
SDSHVRLSYATDLDTIYKGVERLGQFVRQCLAVRA
CCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]